Understand the risk and biology of smouldering myeloma (SMM) for early detection of symptomatic myeloma. The study will investigate genomic and immune correlates of progression, clonal heterogeneity, and biomarkers using liquid biopsies and T cell phenotype and functionality in SMM.

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The history, advancements, and surgical options for durable hiatal hernia repair. Learn about the signs of symptomatic hiatal hernia and how modern repair techniques differ from prior surgical repairs.

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The ALIGN.AR trial evaluates Trilogy THV system in high-risk patients with severe aortic regurgitation. Untreated AR is linked to high mortality, emphasizing the need for safe alternative interventions like TAVR devices. The study aims to demonstrate safety and effectiveness of the Trilogy valve in

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Estimated influenza disease burden in the United States from the 2010-11 season through the 2022-23 season, including symptomatic illnesses, medical visits, hospitalizations, and deaths. The data provides insights into the impact of influenza over the years and preliminary estimates for the upcoming

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Dengue is an epidemic disease caused by the dengue virus transmitted by mosquitoes. It affects millions of people each year, leading to severe symptoms such as fever, rash, and body pain. Early detection through laboratory tests is crucial to prevent complications. Proper management, including preve

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Newborn screening is a screening program for infants under which pre-symptomatic congenital conditions are detected so that treatment can be commenced as soon as possible to prevent or reduce the long-term consequences of the disease. These programs are usually run by the national or state governing

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This ASTRO clinical guideline focuses on the use of external beam radiation therapy for palliation of symptomatic bone metastases, emphasizing its efficacy in pain management and local symptom control. Updated evidence and recommendations address the evolving landscape of metastatic cancer treatment

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Bioidentical Hormone Replacement Therapy (BHRT) involves using compounded hormones that are chemically identical to the hormones in the human body. Customized compounded bioidentical hormones offer flexible dosing based on individual needs, with growing clinical validation for hormone optimization.

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Autoimmunity Screening for Kids (ASK) conducted a study in Colorado on over 30,000 children aged 1-17, revealing a 1.0% prevalence of pre-symptomatic Type 1 Diabetes (T1D) and a 2.1% prevalence of celiac disease/autoimmunity. The screening showed a significant reduction in Diabetic Ketoacidosis (DKA

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Long Covid, also known as post-Covid condition, refers to persistent symptoms lasting at least 2 months after the initial Covid-19 infection. Symptoms can include fatigue, shortness of breath, and cognitive dysfunction, impacting daily life. Around 10-30% of Covid patients may experience Long Covid,

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A 58-year-old man with a history of diabetes and hypertension presents with fever and abdominal pain, raising multiple differential diagnoses including symptomatic AAA, pyelonephritis, acute appendicitis, complicated urolithiasis, or diabetic ketoacidosis. The case explores clinical manifestations,

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The Ministry of Health & Family Welfare in India has issued revised guidelines for home isolation of very mild/pre-symptomatic/asymptomatic COVID-19 cases. Patients eligible for home isolation must have the necessary facility for self-isolation. Special considerations apply to elderly patients and t

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COVID-19, caused by the new coronavirus, presents mild to severe symptoms and spreads through close contact. Older individuals and those with underlying conditions are at higher risk. There is no specific treatment yet, but symptoms can be managed. Prevention measures include frequent handwashing, c

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Dr. Mohammad Ahmad El Khayyat, an Assistant Professor in Dermatology, STDs, and Andrology, details the diagnostic methods and tests for gonorrhea. Various tests including Gram stain, culture, antigen detection tests, and nucleic acid amplification tests are discussed, highlighting sensitivity and sp

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Urinary tract infections are common bacterial infections during pregnancy, with asymptomatic bacteriuria being prevalent. If left untreated, asymptomatic bacteriuria can lead to symptomatic infection, but proper treatment with antimicrobial agents can prevent complications. Treatment options include

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Adults (>18 yrs) presenting with symptomatic ear wax often seek interventions like olive oil drops or alternative ear wax solvents. A study compared the efficacy of olive oil drops in conjunction with syringing versus alternative treatments or no treatment. PubMed search yielded 26 papers, with 2 re

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Introduction to the surveillance of Severe Acute Respiratory Illness (SARI) with a focus on COVID-19 cases and clusters. The monitoring of hospitalized SARI cases, identification of unlinked cases, and implementation of control measures to reduce transmission are highlighted. Criteria for defining S

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Cough is a vital reflex that helps clear irritants from the respiratory tract. Antitussives suppress cough reflex, with varying mechanisms of action. Different types of drugs are used in the symptomatic treatment of cough, classified based on their modes of action. Dextromethorphan and codeine are c

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Explore the comprehensive pathway for children with Long COVID in the HIOW region, including definitions, symptoms, and management strategies. Learn about the signs and symptoms of Acute COVID-19, ongoing symptomatic COVID-19, and Post-COVID-19 syndrome. Discover the challenges faced by non-hospital

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Discussing the challenges and gaps in the medical management of PAD, this presentation by Dr. Faisal Latif highlights the unique issues faced by patients with PAD and the limitations of current treatment options. It delves into the current guidelines for symptomatic PAD and explores the findings of

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Special Olympics participants are required to adhere to strict safety guidelines to prevent the spread of COVID-19. This includes staying home if symptomatic, maintaining physical distance, wearing masks, and practicing proper hand hygiene. Participants with high-risk conditions are advised to avoid

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FIT testing was implemented in primary care practices across the South West region in 2018, focusing on symptomatic patients classified as low risk for colorectal cancer. Initial data evaluation revealed a positive predictive value (PPV) of 6.2%, exceeding NICE referral thresholds. SWAG results high

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Learn about the application of quantitative PET/CT imaging for diagnosing and managing stable ischemic heart disease and coronary microvascular dysfunction in symptomatic patients through this insightful talk by Dr. Viviany Taqueti. Discover the limitations of conventional approaches, implications f

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The REPRISE II trial extended cohort evaluated the Lotus Valve System's safety and performance in symptomatic patients with severe aortic stenosis at high risk for surgical valve replacement. This prospective, single-arm study assessed the valve system's effectiveness through various follow-ups and

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Schools are expected to open for all pupils with measures in place to reduce the risk of COVID-19 transmission. Emphasis is on following guidance, maintaining hygiene, implementing preventive measures, and being prepared to respond to confirmed cases. The focus is on sensible, proportionate controls

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Diagnosis and treatment of hyperthyroidism in pregnancy involves consideration of clinical manifestations, establishing the cause (such as Graves Disease or hCG mediated hyperthyroidism), and determining the need for treatment based on the severity of symptoms. Therapeutic options include medication

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Develop and implement a system to place COVID-19 symptomatic or positive individuals who cannot self-isolate into housing. The Housing Triage Team identifies people in need, conducts placement questionnaires, and facilitates housing arrangements, transportation, and testing if required. The team als

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