Surgical Management of Hiatal Hernia
The history, advancements, and surgical options for durable hiatal hernia repair. Learn about the signs of symptomatic hiatal hernia and how modern repair techniques differ from prior surgical repairs.
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ARREST Trial: Expedited Transfer for Non-ST Elevation OHCA
This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the
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Surgical Prophylaxis and Antimicrobial Selection Guidelines in Surgery
Surgical prophylaxis involves administering antibiotics before contamination of previously sterile tissues to prevent infections. Common pathogens in surgical site infections include skin flora like S. aureus. Antimicrobial selection is based on the surgical procedure, likely pathogens, and safety c
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Early Vasopressors in Sepsis Clinical Trial: Improving Patient Outcomes
This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss
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Moein Surgical Arts Spider Vein Surgery in Los Angeles
You're looking for one of the greatest spider vein surgeons in Los Angeles. The most advanced non-surgical and surgical spider vein treatments accessible today are the specialty of Moein Surgical Arts. If you need more information, please visit our website.
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Empagliflozin Effects on Heart Failure with Reduced Ejection Fraction: EMPEROR-Reduced Trial Overview
Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em
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Simulation Techniques in Clinical Trial Design
Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l
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UK Mini Mitral Trial: Minimally Invasive Thoracoscopic Approach vs Conventional Sternotomy for Mitral Valve Repair
The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach
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Understanding Different Types of Hearings in the Court Management System
Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc
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STRESS-L Trial: Study on Reversal of Septic Shock with Landiolol
The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg
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Importance of Surgical Head Coverings in Preventing Surgical Site Infections
Surgical head coverings play a crucial role in preventing surgical site infections by reducing the risk of microbial contamination and transmission in the operating room environment. Guidelines recommend covering the head, hair, and ears to minimize the shedding of microorganisms from surgical staff
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DRAGON Trial: Green Surgery Research Programme Overview
Dmitri Nepogodiev, a Clinical Lecturer in Public Health at the University of Birmingham, leads the DRAGON Trial aiming to compare the effectiveness and sustainability of reusable versus single-use drapes and gowns in surgical settings. With a focus on reducing surgical site infections, carbon footpr
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The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine in Bronchiectasis
The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c
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ACST-2 Trial: Stenting vs. Surgery for Carotid Artery Stenosis
ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic
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Understanding the Criminal Trial Process
The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi
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The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine in Bronchiectasis
The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma
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NCI-MATCH Trial Interim Analysis Results and Status Update
NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,
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Overview of Health Care Regulations and Standards for Surgical Smoke Management
This part of the surgical smoke management toolkit provides an overview of the health care regulations, standards, and guidelines related to surgical smoke. It covers various organizations such as AORN, ANSI, ECRI, IFPN, The Joint Commission, CDC, NIOSH, and OSHA, emphasizing the importance of contr
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Surgical Skin Preparation: Importance and Best Practices
Surgical skin preparation is crucial to reduce microbes and prevent surgical site infections. It involves thorough cleansing to eliminate dirt, oils, and microbes while minimizing the risk of infection. Methods include mechanical friction and using antiseptic solutions like alcohol, iodine, and chlo
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Essential Elements of Clinical Trial Protocols
Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f
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Family Law Trial Skills Workshop: Evidence Collection and Trial Techniques
Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such
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Surgical Hand Antisepsis in the Operating Room Setting
Achieving effective surgical hand antisepsis is crucial in the operating room to reduce the risk of surgical site infections. This involves using antimicrobial agents and sterile brushes to remove debris and microorganisms, reduce microbial counts, and prevent rapid growth. The process requires equi
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Enhancing Clinical Trial Milestone Predictions with nQuery Predict
Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d
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Civil Rights Litigation Steps Overview
Exploring the detailed process of civil rights litigation, covering steps from fact gathering to trial preparation and post-trial activities. The visual presentation showcases key elements such as client retention, complaint filing, discovery phases, trial preparation, and post-trial procedures like
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Civil Jury Trial Simulation: Winter v. TBD, Inc.
Simulation competition where students portray attorneys and witnesses in a civil jury trial based on the case of professional writer Riley Winter suing an online magazine for wrongful termination due to age discrimination. Judges preside over the trial, score performances, and provide feedback, focu
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Preliminary Outcomes of RINSE Trial for Reducing Surgical Site Infections in Ventral Hernia Repair
Jeremy Warren, MD, FACS from the University of South Carolina School of Medicine Greenville shares the preliminary outcomes of the RINSE trial aimed at reducing surgical site infections in ventral hernia repair. The trial explores the use of antibiotic irrigation and its effectiveness in decreasing
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Robotic Surgical Skill Evaluation in Sinus Surgery: A Comprehensive Study
The REMS project focuses on robotic ear, nose, and throat microsurgery systems, with one sub-project aiming to validate if robotic assistance enhances surgical skill compared to traditional methods. A key paper by Ahmidi et al. explores robotic path planning for surgeon skill evaluation in minimally
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Participating in a Mock Criminal Jury Trial Competition
In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer
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AIRWAYS-3 Trial: Advanced Airway Management in In-Hospital Cardiac Arrest
AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o
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Surgical Treatment and Complications in Gynecology: Review of Methods and Outcomes
Exploring the complexities of gynecological surgical procedures, this content delves into historical perspectives on prolapse and incontinence surgeries, the efficacy of various treatment approaches including weight management and surgical interventions like TVT, and the evolution of surgical techni
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The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine for Bronchiectasis
The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit
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Key Aspects of Partnering with a Clinical Trial Unit for Successful Trials
Understanding the role and benefits of partnering with a Clinical Trial Unit (CTU) is essential for potential Chief Investigators. A CTU handles various aspects of trial coordination, from developing trial materials to overseeing regulatory permissions and data management. UK Clinical Trials Units (
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The O.J. Simpson Murder Trial
The trial of O.J. Simpson for the brutal murders of Nicole Brown Simpson and Ron Goldman captivated the nation, with overwhelming evidence implicating Simpson. Despite the compelling case against him, Simpson's defense team, led by Johnnie Cochran, raised doubts about the integrity of the evidence a
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Preparation and Roles for the Trial of King Louis XVI
Participants are preparing for the trial of King Louis XVI by researching charges, roles, and responsibilities. The trial process includes reading indictments, opening statements, questioning phases, and final statements. Each role, including Louis, Marie, Robespierre, Marat, and a woman from the 3r
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AMTA Criminal Jury Trial Competition Overview
Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor
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The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine for Bronchiectasis Patients
The CLEAR Trial, led by Professor Stuart Elborn and Professor Judy Bradley, aims to assess the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves a 2x2 factorial design and various study sites acros
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The CLEAR Trial: Investigating Hypertonic Saline and Carbocisteine for Bronchiectasis Treatment
The CLEAR Trial is a 2x2 factorial randomized trial assessing the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley, the trial involves randomization, sealed
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Surgical Interventions for Vertical Strabismus in Superior Oblique Palsy: A Review
Binocular misalignment in superior oblique palsy often requires surgical interventions to address vertical strabismus, which can lead to visual issues and neck muscle problems. This review assessed the effects of various surgical treatments on individuals with this condition. Despite limited data pr
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Understanding Speedy Trial Rights in Juvenile Cases
Speedy trial rights in juvenile cases are crucial for ensuring timely resolution of legal proceedings. According to Florida laws, the speedy trial time period is 90 days from the date the child was taken into custody or served with a summons. Failure to commence the adjudicatory hearing within this
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Guidance on Intercollegiate Surgical Curriculum Programme Requirements
The Intercollegiate Surgical Curriculum Programme (ISCP) overseen by the Joint Committee on Surgical Training sets out annual requirements for surgical trainees, including assessments, feedback, and audits. Pitfalls to avoid include last-minute preparations and failing to reflect on learning experie
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