The history, advancements, and surgical options for durable hiatal hernia repair. Learn about the signs of symptomatic hiatal hernia and how modern repair techniques differ from prior surgical repairs.

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This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the

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Surgical prophylaxis involves administering antibiotics before contamination of previously sterile tissues to prevent infections. Common pathogens in surgical site infections include skin flora like S. aureus. Antimicrobial selection is based on the surgical procedure, likely pathogens, and safety c

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Sound knowledge of the anatomy of the periodontium and surrounding tissues is essential for successful periodontal and implant surgical procedures. This includes understanding the mandible and maxilla anatomy, muscles, anatomic spaces, and landmarks like the mandibular canal. Proper awareness can he

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Clinical scenario involving a 24-year-old male post-appendicectomy presenting with abdominal pain and concerns of wound infection. The tutorial discusses surgical wound infections, risk factors, prevention strategies, and principles of management, providing insights for approaching such cases as a s

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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You're looking for one of the greatest spider vein surgeons in Los Angeles. The most advanced non-surgical and surgical spider vein treatments accessible today are the specialty of Moein Surgical Arts. If you need more information, please visit our website.

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Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em

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Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l

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The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach

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Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc

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The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg

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Surgical head coverings play a crucial role in preventing surgical site infections by reducing the risk of microbial contamination and transmission in the operating room environment. Guidelines recommend covering the head, hair, and ears to minimize the shedding of microorganisms from surgical staff

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Dmitri Nepogodiev, a Clinical Lecturer in Public Health at the University of Birmingham, leads the DRAGON Trial aiming to compare the effectiveness and sustainability of reusable versus single-use drapes and gowns in surgical settings. With a focus on reducing surgical site infections, carbon footpr

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi

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The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma

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NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

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This part of the surgical smoke management toolkit provides an overview of the health care regulations, standards, and guidelines related to surgical smoke. It covers various organizations such as AORN, ANSI, ECRI, IFPN, The Joint Commission, CDC, NIOSH, and OSHA, emphasizing the importance of contr

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Surgical skin preparation is crucial to reduce microbes and prevent surgical site infections. It involves thorough cleansing to eliminate dirt, oils, and microbes while minimizing the risk of infection. Methods include mechanical friction and using antiseptic solutions like alcohol, iodine, and chlo

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Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f

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Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such

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Achieving effective surgical hand antisepsis is crucial in the operating room to reduce the risk of surgical site infections. This involves using antimicrobial agents and sterile brushes to remove debris and microorganisms, reduce microbial counts, and prevent rapid growth. The process requires equi

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Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d

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Exploring the detailed process of civil rights litigation, covering steps from fact gathering to trial preparation and post-trial activities. The visual presentation showcases key elements such as client retention, complaint filing, discovery phases, trial preparation, and post-trial procedures like

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Simulation competition where students portray attorneys and witnesses in a civil jury trial based on the case of professional writer Riley Winter suing an online magazine for wrongful termination due to age discrimination. Judges preside over the trial, score performances, and provide feedback, focu

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Jeremy Warren, MD, FACS from the University of South Carolina School of Medicine Greenville shares the preliminary outcomes of the RINSE trial aimed at reducing surgical site infections in ventral hernia repair. The trial explores the use of antibiotic irrigation and its effectiveness in decreasing

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The REMS project focuses on robotic ear, nose, and throat microsurgery systems, with one sub-project aiming to validate if robotic assistance enhances surgical skill compared to traditional methods. A key paper by Ahmidi et al. explores robotic path planning for surgeon skill evaluation in minimally

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In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer

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AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o

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Exploring the complexities of gynecological surgical procedures, this content delves into historical perspectives on prolapse and incontinence surgeries, the efficacy of various treatment approaches including weight management and surgical interventions like TVT, and the evolution of surgical techni

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The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit

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Understanding the role and benefits of partnering with a Clinical Trial Unit (CTU) is essential for potential Chief Investigators. A CTU handles various aspects of trial coordination, from developing trial materials to overseeing regulatory permissions and data management. UK Clinical Trials Units (

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The trial of O.J. Simpson for the brutal murders of Nicole Brown Simpson and Ron Goldman captivated the nation, with overwhelming evidence implicating Simpson. Despite the compelling case against him, Simpson's defense team, led by Johnnie Cochran, raised doubts about the integrity of the evidence a

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Participants are preparing for the trial of King Louis XVI by researching charges, roles, and responsibilities. The trial process includes reading indictments, opening statements, questioning phases, and final statements. Each role, including Louis, Marie, Robespierre, Marat, and a woman from the 3r

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor

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The CLEAR Trial, led by Professor Stuart Elborn and Professor Judy Bradley, aims to assess the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves a 2x2 factorial design and various study sites acros

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The CLEAR Trial is a 2x2 factorial randomized trial assessing the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley, the trial involves randomization, sealed

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Binocular misalignment in superior oblique palsy often requires surgical interventions to address vertical strabismus, which can lead to visual issues and neck muscle problems. This review assessed the effects of various surgical treatments on individuals with this condition. Despite limited data pr

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