Explore various physical and chemical methods used for gene transfer, including electroporation, particle bombardment, microinjection, ultrasound, and bacterial transformation. Learn how DNA enters the nucleus and the role of retroviruses in gene transfer efficiency. Understand the process of RNA co

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This article provides insights into the status, regulatory considerations, and delivery methods of gene therapy and genome editing technologies. It discusses approved gene therapies in the US, human genome editing in clinical applications, and the regulatory authority of the FDA over gene therapy. T

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Exploring the mechanisms of gene delivery via viral vectors, this content delves into the basics of viral structure, infection, and replication. It discusses common viral vector systems like Adenoviral and Lentiviral vectors, highlighting safety considerations and the production processes involved.

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Explore the fascinating world of CRISPR/Cas9 gene editing technology through sessions led by experts like Roy Campbell and Howard Robinson. Delve into the working of gene editing, the CRISPR system, and the role of Cas9 enzyme. Learn about CRISPR's origin in prokaryotic organisms and its potential f

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Gene expression is a crucial process that leads to the production of functional gene products like RNA and proteins. This article explores the regulation of gene expression in both prokaryotes and eukaryotes, covering the importance of regulating gene expression, types of regulation elements, specif

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Bioinformatics involves analyzing biological sequences through sequence alignment to uncover functional, structural, and evolutionary insights. This process helps in tasks like annotation of sequences, modeling protein structures, and analyzing gene expression experiments. Basic steps include compar

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Gene set enrichment tests help identify functional gene sets enriched in hit lists compared to background sets. Various biases (technical, biological, statistical) can lead to incorrect conclusions in data analysis, emphasizing the importance of recognizing and addressing them. Technical biases like

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Delve into the world of genetics and genomics through the lens of integrative biology, investigating the differences between cell types, the rationale for gene expression profiling, and the analysis of differential gene expression in various diseases. Uncover the significance of gene ontology, co-ex

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Reference services in libraries play a crucial role in connecting users with the information they need, promoting the use of library collections. This service assists users in various queries and requests, ranging from simple fact-finding to complex research. Reference functions include responsive s

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Motion is defined as a change in position over time. To describe motion accurately, one needs to understand frames of reference and relative motion. Frames of reference are systems of objects used to determine if something is in motion, while relative motion involves movement in relation to a refere

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This content provides information on the Summer Institutes of Statistical Genetics module, focusing on gene expression profiling. It includes details on the schedule, experimental design, RNA sequencing workflow, modes of bulk RNA sequencing, and RNASeq software. The content discusses crucial steps

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Gene mutations play a significant role in molecular biology, leading to alterations in DNA sequences that can impact offspring. These mutations can arise spontaneously or be induced by various factors, such as mutagens. Understanding gene mutations is crucial for comprehending the genetic basis of c

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Explore the E-Catalog featuring various laboratory equipment such as the Analyticon Biolyzer 100 Chemistry Analyzer, Boeco Centrifuge C28A, and Eschweiler Blood Gas Analyzer. View specifications, prices, education materials, and procedures for these advanced laboratory tools. The catalog includes es

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Gene drive technology is a cutting-edge approach aimed at combating malaria by spreading genetically modified genes in mosquito populations. This technology has the potential to protect endangered species and conserve nature. However, successful implementation requires complex collaborations, risk a

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This presentation delves into the intricate concepts of gene duplication, DNA mutation, and read mapping in the context of molecular evolution. It explains the various types of mutations, the significance of gene duplication in generating new genetic material, and the process of read mapping to alig

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Gene therapy involves introducing DNA into a patient to treat genetic diseases by correcting disease-causing mutations. There are two types of gene therapy: somatic gene therapy and germline gene therapy, each with different implications. Techniques such as gene augmentation therapy and gene inhibit

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Explore the process of constructing reference planes in engineering, including principal planes, creating reference planes, reference features, and how to uniquely define a plane. Reference planes are essential for creating new sketches and carrying out feature operations in engineering design.

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Learn how to download a list of all carbapenem resistance genes and point mutations from the NCBI Reference Gene Catalog for pathogen detection. Follow step-by-step instructions on accessing the catalog, applying filters to select carbapenem subclass, and downloading the data in tab-delimited format

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This comprehensive content delves into the intricate mechanisms of gene regulation and control of gene expression. It covers topics such as transcriptional regulation, bacterial genes classification, and the role of regulatory proteins. Explore how genes are regulated at transcription, translation,

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Explore the dynamic world of gene expression with the Chunky and Chips Gene Expression Group at the University of Notre Dame. Dive into topics like transcription, translation, and cellular events influencing gene expression. Delve into real-world scenarios and gain insights into the cellular level b

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Explore the goes.virtual Winter 2022 Catalog featuring exciting virtual cooking events and classes. The Cooking School offers a platform for culinary exploration and networking opportunities. Join classes like Pizza at Home, Pasta & Sauce 101, and Bake Together for a fun and interactive cooking expe

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Explore the essence of conducting reference interviews, understanding the advantages and disadvantages, essential personal and interpersonal skills, and guidelines for behavioral performance in providing reference and information services. Delve into the remote reference service concept, the integra

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The partnership between Ladd Library at Bates, Hawthorne-Longfellow Library at Bowdoin, and Miller Library at Colby, known as CBB, has significantly contributed to the effective coordination of collection development and catalog sharing for over two decades. Retention agreements, standardized loan p

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Epistasis is a phenomenon where the phenotypic expression of one gene is influenced by interactions with another gene. This concept, first introduced in 1909, plays a crucial role in genetics, affecting various traits and evolutionary processes. The difference between dominance and epistasis lies in

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The Gene Wiki Jamboree FaceBase Spring Meeting in 2010 aimed to create collaboratively-written and community-reviewed review articles for every gene in the human genome and every concept relevant to FaceBase. It highlighted the value of such articles, providing quick summaries and compilations of re

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Learn how to effectively utilize the Fisher Scientific punch-out catalog in the Supplier Relationship Management (SRM) system for purchasing laboratory supplies. This guide covers setting up roles, accessing the catalog, ordering procedures, and tips for procurement within the SRM system at the Univ

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Dive into a tutorial on utilizing the new online catalog system, Follett Destiny, implemented over the summer for Leyton Students. Learn how to log in, access the catalog, search for books, explore by author, and more. Discover step-by-step instructions and tips to navigate the new library system ef

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This supplementary data includes raw data from agarose gel electrophoresis showing gene expression levels for human SOX17, FOXA2, AFP, ALB, and ACTB in various cellular samples. The gel images depict the expected sizes of amplicons for each gene in different conditions and time points of cell cultur

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In this project, the focus is on identifying splice sites relevant to the inhibitory dopamine receptor gene (D2). The problem involves finding splicing elements within a specific range of known splice sites in the gene. The data provided includes the D2 gene entry in FASTA format, a database of spli

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This guide provides detailed instructions for using the Steelcase e-catalog within the Supplier Relationship Management (SRM) system at the University of Kentucky. It covers how departmental staff can place orders, the role of SRM Shopper, accessing the catalog through myUK, customization options, o

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Reverse genetic approaches involve mutating a target gene to observe its phenotypic effects, providing insights into the gene's normal function. Techniques like gene knockout, knockdown, and homologous recombination are used to manipulate genes and study genetic pathways, leading to discoveries in v

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The lecture covers the essential aspects of hypothesis testing in gene expression profiling, emphasizing experimental design, confounding factors, normalization of samples, linear modeling, gene-level contrasts, t-tests, ANOVA, and significance assessment techniques. Practical insights are shared on

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Leyton School Library has transitioned to the new online catalog system, Follett Destiny, to enhance users' access to library resources. This tutorial guides users on logging in, searching for books by author or title, and exploring various functionalities to improve proficiency in utilizing the onl

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Exploring the fundamentals of genetics engineering, this lecture covers topics such as DNA structure, gene expression, gene function, genome, mutation, recombination, and genetic modification. Understand the significance of DNA, genes, and the processes involved in gene expression. Dive into the wor

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Expression vectors are designed to facilitate gene expression by carrying essential elements such as promoters, terminators, and fusion tags. They allow precise control over gene regulation for transcription and translation in host cells, enabling efficient protein production. Different promoters li

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In this project, the Cstps-1 gene from Citrus sinensis is being cloned to produce the enzyme Citrus Valencene Synthase (CVS) responsible for generating the fragrant valencene compound. The process involves DNA isolation from a Valencia orange, gene amplification, vector transformation, and testing f

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This presentation discusses the collaborative effort by a team of professionals to revamp a library catalog for the Georgia Department of Transportation's Roy A. Flynt Memorial Library. The project stemmed from a need for a better library catalog identified during discussions with GDOT employees. Th

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Multiple enhancers play a crucial role in regulating gene expression in a cell, with approximately 3-5 enhancers associated per human gene. These enhancers are essential for tissue-specific expressions and are active within the same cell line. The use of multiple enhancers can impact gene expression

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MobiSlide is the first interactive, manageable, and mobile sales and marketing solution that revolutionizes catalog creation. Developed by a team of friends, it quickly gained traction, leading to a decision to bring the project to Israel and apply to Microsoft Ventures. With real-world case studies

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Workshop outcomes and discussions from the MDA-NINDS Workshop on Best Practices for Gene Therapy Programs, highlighting key challenges, possible solutions, and the impact on translational funding programs. The workshop format included orienting talks and panels focusing on scientific premise, regula

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