Transfusion
Blood transfusion is a crucial medical procedure worldwide, with various components like packed red blood cells, plasma, platelets, and cryoprecipitate being utilized for efficient use. Differential centrifugation is employed for component preparation, ensuring precise separation of red blood cells,
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Pathogen-reduced platelets: clinical highlights
Pathogen-reduced platelets play a crucial role in reducing the risk of transfusion-transmitted infections through pathogen inactivation technology (PIT). This technology provides an additional layer of safety against various pathogens including viruses, bacteria, protozoa, and leukocytes. Platelet c
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Update on Pathogen Reduction of Platelets at National Haemovigilance Conference 2023
This update covers the latest developments in pathogen reduction of platelets, including the introduction of whole blood containing platelets. Key strategic initiatives focus on assessing post-collection blood product manipulation processes and developing new products to meet healthcare needs. The a
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Understanding Immune Thrombocytopenia (ITP) and Its Impact
Immune Thrombocytopenia (ITP) is a rare autoimmune disease where the immune system wrongly attacks platelets, leading to low platelet count. It can affect individuals of all ages, with symptoms appearing post-virus, vaccination, or certain medications. ITP can result in fatigue, bruising, and bleedi
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Hematopoiesis: Processes and Niches in the Human Body
Hematopoiesis, the process of daily blood cell production, involves maintaining the physiological balance of circulating blood cells. It includes the generation of billions of erythrocytes, platelets, and leukocytes to meet the body's needs. The location of hematopoiesis changes throughout human lif
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Chronic Myeloid Leukemia
Chronic myeloid leukemia (CML), or chronic myelogenous leukemia, is a slow-growing form of cancer that affects the bone marrow and blood. Like acute myeloid leukemia, CML originates in the myeloid cells. When functioning properly, myeloid cells produce mature red blood cells, platelets and non-lymph
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Understanding the Components of Blood for Better Health
Explore the main components of blood such as red blood cells, white blood cells, platelets, and plasma. Learn how these components function, their percentages in blood, and how they impact human health. Discover the importance of blood donation and how changes in blood composition can affect overall
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Bone Marrow Transplant Cost in India
The supple, fatty tissue found inside your bones is called bone marrow. The cells that make blood and platelets are found in bone marrow, which also produces billions of new blood cells daily.\nA bone marrow transplant (BMT) includes using healthy blood-forming stem cells to replace the patients' di
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Anagrelide 0.5mg: An Effective Treatment for Essential Thrombocythemia
Efficacy and Dosage Efficacy & Dosage Efficacy of Anagrelide (0.5mg) What is Anagrelide? Essential thrombocythaemia is a condition in which an excessive amount of platelets are present in the blood. Anagrelide 0.5 mg inhibits the production of platelets, thereby reducing the risk of blood clotting,
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Understanding Blood Transfusion: Components, Preparation, and Safety Measures
Blood transfusion is a crucial medical procedure involving the transfusion of different blood components to patients in need. This practice has evolved to include various components such as packed red blood cells, plasma, platelets, and more. The preparation of these components involves specific tec
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Understanding Blood Cells and Their Functions in the Circulatory System
Blood is comprised of cells and plasma that circulate within the closed circulatory system. The formed elements include erythrocytes, platelets, and leukocytes, each playing vital roles in oxygen transport, defense against infection, and nutrient distribution throughout the body. The hematocrit esti
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Understanding Health and Science: Circulatory System, Forces, and Geography Insights
Exploring the intricate workings of the circulatory system that transports blood, key components like white blood cells, red blood cells, and platelets, and the forces like friction and air resistance. Delve into geography insights focusing on Brazil and its grid references, temperature, currency, l
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Understanding Coagulants, Anti-Coagulants, and Blood Components in Pharmaceuticals
Mrs. Sashmitha Samuel, an Associate Professor in the Department of Pharmaceutical Chemistry, delves into the importance of coagulants, anti-coagulants, and the components of blood. Blood, a vital fluid in the body, carries nutrients, oxygen, and helps remove waste products. Learn about the process o
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Understanding Blood Cells and Transport Mechanisms
Your blood, consisting of red blood cells, white blood cells, platelets, and plasma, plays a crucial role in transporting substances like oxygen, nutrients, and waste products throughout your body. Red blood cells are specialized for oxygen transport due to their unique adaptations, while white bloo
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Hemostasis and Blood Coagulation Mechanisms Explained
Hemostasis refers to the prevention of blood loss through vascular constriction, platelet plug formation, blood clotting, and fibrous tissue growth. Vascular constriction occurs immediately after vessel damage, initiated by myogenic spasm, autacoid factors, and nervous reflexes. Platelet plug format
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Understanding Hemostasis: Key Concepts in Blood Clotting Mechanisms
Hemostasis, crucial for preventing blood loss, involves platelet formation, clotting factors, and fibrinolysis. This process includes vessel constriction, platelet activation, clot formation, and fibrin breakdown. Platelets, produced in the bone marrow, play a vital role in maintaining vascular inte
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Exploring the Components of the Circulatory System
The circulatory system, comprising the heart, blood vessels, and various components like arteries, veins, and capillaries, plays a crucial role in distributing oxygen, nutrients, and waste products throughout the body. The heart pumps blood through a double circulatory system, ensuring oxygenation o
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Understanding Platelet Count and its Importance in Blood Clotting
Platelets, also known as thrombocytes, play a crucial role in blood clotting. This article explains the structure and lifespan of platelets, the purpose of performing a total platelet count, and the principle of counting platelets using a hemocytometer. It also describes the components used for plat
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Understanding Autacoids: Local Hormones and Their Role in the Body
Autacoids, also known as local hormones, are substances produced by various tissues that act locally to regulate the activity of smooth muscles, nerves, platelets, and other tissues. They play a crucial role in pain, inflammation, allergic reactions, and more. Serotonin, a key autacoid, has diverse
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Platelet Guidance: Bacterial Risk Control Strategies in Transfusion Services
Platelet transfusions carry the risk of bacterial contamination leading to severe infections and fatalities. FDA regulations mandate control strategies to mitigate this risk, such as implementing testing strategies and adhering to specific guidelines for platelet storage and handling. Understanding
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Understanding Blood Components and Their Administration
Effective blood transfusion therapy relies on the availability and proper administration of various blood components. Separating blood components allows for better patient care by matching transfusions to individual needs and avoiding unnecessary components. Different blood products like packed red
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Understanding the Circulatory System: Functions and Components
The circulatory system, comprised of pulmonary and systemic circulation, plays a crucial role in transporting oxygen, nutrients, and waste products throughout the body. It consists of the heart, arteries, veins, and capillaries which work together to ensure proper circulation. Blood, the carrier of
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Understanding Platelet Structure and Function in Physiology
Platelets play a crucial role in hemostasis and bleeding disorders. This lecture by Dr. Mohammed Alotaibi covers the ultrastructure of platelets, functions of organelles and surface receptors, mechanisms of platelet functions, and the relationship of membrane receptors and granule content in normal
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Understanding Complete Blood Count (CBC) Test
Complete Blood Count (CBC) is a panel of tests that evaluates different types of blood cells, including red blood cells, white blood cells, and platelets. CBC helps diagnose various blood disorders and monitor conditions that affect blood cells, such as anemia or infections. The test is ordered base
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Understanding Blood Components and Microhaematocrit Procedure in Physiology Lab
Blood is a complex fluid composed of various components like platelets, erythrocytes, and leukocytes suspended in plasma. Microhaematocrit is a technique used to measure hematocrit levels in blood. The process involves collecting blood in a capillary tube, centrifuging it to separate the layers, and
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Understanding the Basics of Blood and Transfusions
Blood is a vital tissue that performs essential functions like delivering oxygen and nutrients, maintaining immunity, and controlling body temperature. Blood transfusions save lives by treating accident victims, transplant recipients, cancer patients, and those with blood-related diseases. Component
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Blood Transfusion in Surgery: Types and Indications
Blood transfusion plays a crucial role in surgery, with different blood products such as whole blood, packed red cells, fresh-frozen plasma, cryoprecipitate, and platelets being used based on specific needs. Understanding the indications and proper handling of blood products is essential for safe tr
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Overview of Blood and Hematology: Functions and Composition
The human body consists mostly of water, with blood making up approximately 8% of body weight. Blood is composed of plasma and formed elements, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets. Plasma, the liquid part of blood, contains various proteins such as
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Understanding the Importance of Blood Composition and Functions
Blood is a complex tissue composed of red cells, white cells, platelets, and plasma, each serving crucial functions such as oxygen transport, waste removal, and immune system support. Red cells contain hemoglobin for oxygen transport, while white cells play a key role in defending the body against i
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Understanding Blood: Composition and Functions
Blood is a vital fluid tissue in the human body, classified as a connective tissue. It consists of living cells known as formed elements suspended in a non-living matrix called plasma. The physical characteristics of blood, such as color range, pH level, and temperature, play crucial roles in mainta
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Understanding the Components and Functions of Blood
Explore the intricate details of blood, the river of life, including its components such as formed elements, plasma, leukocytes, platelets, and the process of hematopoiesis. Learn about the physical traits of blood, the role of proteins in plasma, types of leukocytes, and the importance of platelets
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Threshold for Platelets Study: Prospective Trial on Platelet Transfusion
This study aims to determine the platelet count threshold for critically ill patients prior to invasive procedures. The trial update includes information on open sites, current recruitment status, and eligibility criteria. The agenda for the meeting covers trial updates, eligibility queries, screeni
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