The multistep process of carcinogenesis at both phenotypic and genetic levels, including excessive growth, local invasion, and metastasis. Explore the six changes in normal cell physiology that result in cancer formation and the mechanisms of action of oncoproteins. Discover the role of important ge

6 views • 17 slides

Critiquing the traditional media effects research, this analysis highlights concerns such as methodology, theoretical adequacy, and generalizability. It questions the effectiveness of the effects model in tackling social problems, treating children as inadequate, and blaming victims without consider

2 views • 21 slides

The inductive effect in organic chemistry is the polarization of a bond due to electron-donating or withdrawing effects of adjacent groups, leading to a degree of polarity in the bond. This effect is distance-dependent and can be either electron-withdrawing or electron-releasing. On the other hand,

0 views • 12 slides

Network-based interpretation and integration play a crucial role in understanding genetic perturbations in biological systems. Perturbations in networks can affect nodes or edges, leading to valuable insights into gene function and phenotypic outcomes. Various algorithms, such as graph diffusion and

0 views • 55 slides

Myeloproliferative neoplasms (MPNs) include a group of disorders characterized by overproduction of blood cells. The WHO classification outlines eight disorders with varied clinical presentations and potential for transformation. These disorders, such as CML, CNL, and PV, exhibit significant phenoty

2 views • 58 slides

Industrial toxicology is a vital field that studies the effects of various agents on organism health through mechanisms of action, toxicokinetics, and more. It explores toxic chemical absorption, distribution, metabolism, and elimination, as well as toxic effects on major organ systems. Learn about

0 views • 35 slides

Epistasis is the interaction between genes where one gene's allele masks the expression of another gene. Various types of epistasis, such as dominant and recessive epistasis, can be observed, impacting the phenotypic ratios. Statistical inferences can help analyze epistatic interactions in genetic s

0 views • 35 slides

This presentation by Richard Williams from the University of Notre Dame discusses the importance of adjusted predictions and marginal effects in interpreting results. It explains factor variables, different approaches to adjusted predictions, and uses NHANES II data to demonstrate concepts. The talk

0 views • 49 slides

Cyclones and tsunamis are natural disasters that can have devastating effects such as strong winds, heavy rains, floods, and destruction. Cyclones are violent storms with high-speed winds rotating around a calm center of low pressure, while tsunamis are seismic sea waves caused by earthquakes or und

0 views • 9 slides

Exploring the immediate and long-term effects of exercise on the cardiovascular system reveals the remarkable adaptations and responses the body undergoes. From short-term increases in heart rate and blood pressure to long-lasting changes in cardiac output, exercise plays a crucial role in enhancing

0 views • 13 slides

This session covers the differences between cocaine and methamphetamine, focusing on their effects on the brain, particularly the role of dopamine. It explains how dopamine influences pleasure, motivation, and various responses in the body. Imbalance in dopamine levels can lead to a range of symptom

0 views • 20 slides

Energy drinks are popular beverages containing caffeine and other ingredients that claim to boost energy. This article explores common ingredients, the effects of caffeine, risks associated with excessive consumption, and potential side effects of additives like B vitamins, ginseng, and ginkgo bilob

0 views • 13 slides

Vaping, the inhaling of vapor from electronic cigarettes, raises concerns due to unknown long-term effects and reports of serious lung damage. The difference between smoking and vaping lies in nicotine delivery methods. Misconceptions around vaping being healthy are debunked through discussions on i

1 views • 18 slides

Toxicology is the study of adverse effects of chemicals on living organisms. It assesses probability of occurrence, quantitatively and qualitatively analyzing toxic effects. Toxicants are agents causing harmful responses in biological systems. Environmental toxicology focuses on pollutants' effects

0 views • 12 slides

Explore the concept of interaction effects in composite-based structural equation modeling (SEM) through topics like the logic of interaction, estimating effects, multigroup analysis, and visualizing effects. Learn about moderators, their role in relationships between variables, and techniques for a

1 views • 23 slides

Dive into Session 7 of the ARIDE program to explore the prevalence of drug and alcohol use, the concept of polydrug impairment, and the potential effects of combining different substances. Learn about null effects, overlapping effects, and how various drug combinations can impact impairment indicato

0 views • 18 slides

Factorial designs in experiments allow researchers to study the effects of multiple independent variables simultaneously. This type of design enables the examination of main effects and interactions between factors, providing a comprehensive understanding of the research variables. Main effects refe

1 views • 25 slides

Explore the magnetic field and field lines, understand the magnetic effects of current-carrying conductors, learn about the right-hand thumb rule, and discover the magnetic field due to current through a circular loop in Chapter 13 of Magnetic Effects of Electric Current in Science Class at Sainik S

0 views • 17 slides

Corticosteroids, including glucocorticoids and mineralocorticoids, play vital roles in intermediary metabolism, immune responses, and inflammation regulation. They bind to specific receptors in the cell, entering the nucleus to influence gene transcription and protein production. These hormones have

14 views • 32 slides

Corticosteroids are steroid hormones produced by the adrenal cortex, classified into glucocorticoids and mineralocorticoids. Glucocorticoids have diverse effects on metabolism, immune responses, and inflammation, whereas mineralocorticoids regulate electrolyte balance. Mechanistically, corticosteroi

1 views • 32 slides

Biostatistics and computer applications play a key role in the design of experiments in animal genetics and breeding. Proper allotment of treatments to experimental units is crucial to study treatment effects accurately. Designing experiments helps in maximizing information from available resources,

0 views • 37 slides

Variance and its components play a crucial role in analyzing the distribution of quantitative traits in populations. By measuring the degree of variation through statistical methods like Measures of Dispersion, researchers can gain insights into the scatterness of values around the mean. Partitionin

1 views • 22 slides

Explore the concept of Time-Varying Effects Models (TVEM) and why they are essential in analyzing interventions over time. Learn how TVEM differs from traditional regression models by incorporating time to evaluate changes in effects dynamically.

1 views • 35 slides

In this collection of images and descriptions, various aspects of group analyses in neuroimaging research are explored, including statistical parametric mapping, first-level analyses, and assessing different subjects using fixed effects, random effects, and mixed effects analysis. The content delves

1 views • 38 slides

Chemical mediators of inflammation play a pivotal role in inducing specific events during acute inflammation. These mediators are produced in response to various triggers, including microbial products and host proteins, leading to a cascade of inflammatory responses. Understanding the sources and ef

1 views • 43 slides

Alcohol consumption affects the brain and body in various ways, leading to both short-term and long-term detrimental effects. From initial euphoria to later sedation and impaired decision-making, alcohol can cause serious health issues like liver damage and cardiovascular problems. Additionally, beh

0 views • 22 slides

Heritability is a crucial concept in animal genetics and breeding, indicating the proportion of total phenotypic variance attributed to genetic effects. It helps in predicting breeding values, assessing relationships between individuals, and guiding genetic determinations. Properties of heritability

2 views • 20 slides

This lecture by Dr. Zaid Shaker Naji delves into the biological effects of radiation, including deterministic and stochastic effects. It covers mechanisms of damage at the cellular level, such as direct and indirect damage, and discusses somatic and genetic damages that can arise following exposure.

0 views • 10 slides

Explore genetic inheritance through traits, gene expression differences between males and females, and Punnett square analysis. Discover the randomness of genetics, sex-linked, sex-limited, and sex-influenced inheritance, along with practical examples in animal breeding. Delve into genotypic and phe

0 views • 21 slides

Enhance your literature search skills for sequence variant analysis with tips on effective use of variant nomenclature, sources for finding articles for ACMG criteria application, and tools like HGMD, ClinVar, MasterMind, Google, and Google Scholar. Discover the importance of functional studies, cas

0 views • 21 slides

Regression models help analyze effects of independent variables (IVs) on dependent variables (DVs, like weight loss from exercise time). Interactions explore how one IV's effect can be modified by another IV (moderating variable, MV). In this seminar's purpose, techniques to estimate, test, and grap

0 views • 137 slides

ISU's Plant Science Institute is tackling sustainability challenges in agriculture by using predictive models based on genotypic, phenotypic, and environmental data. Through collaborations and investments in scholars, the institute aims to enhance plant breeding programs, improve crop resilience to

0 views • 8 slides

Understanding causal effects through methods like propensity score weighting is crucial in institutional research. This approach helps in estimating the impact of various interventions, such as a writing program, by distinguishing causation from correlation. The use of propensity score matching aids

0 views • 22 slides

Test your knowledge on genetics with these quiz questions covering topics like Mendelian laws, dominant and recessive traits, gamete formation probabilities, and genetic crosses. Explore concepts such as allelic inheritance, phenotypic ratios, and genetic probabilities in various scenarios. Improve

1 views • 79 slides

Chromosome aberrations are deviations from the normal set of chromosomes, which can involve changes in chromosome number, gene arrangement, and appearance. These aberrations can be associated with genetic diseases and species differences. They encompass alterations in the number of genes within a ch

0 views • 7 slides

Epistasis is a phenomenon where the phenotypic expression of one gene is influenced by interactions with another gene. This concept, first introduced in 1909, plays a crucial role in genetics, affecting various traits and evolutionary processes. The difference between dominance and epistasis lies in

0 views • 41 slides

Genetic variation is crucial for evolution, providing the raw material for adaptation and species diversity. Phenotypic variation can arise from differences in genotype, environment, or their interaction. Studying genetic variation through statistical analysis and at the molecular level helps us unr

0 views • 47 slides

American psychologists have traditionally believed in strong media effects, attributing direct influence on audiences. However, the limited effects theory emerged in the 1940s, challenging this notion by suggesting media's negligible impact on behaviors such as voting. On the other hand, proponents

0 views • 6 slides

This content delves into the quantitative genetics of disease, exploring concepts like liability threshold models, phenotypic liabilities, normality assumptions, and genetic factors' contribution to disease variance. It examines how disease prevalence and heritability correlate with affected individ

0 views • 24 slides

Reverse genetic approaches involve mutating a target gene to observe its phenotypic effects, providing insights into the gene's normal function. Techniques like gene knockout, knockdown, and homologous recombination are used to manipulate genes and study genetic pathways, leading to discoveries in v

0 views • 6 slides