The natural history of disease development outlines the progression of a disease in an individual without intervention, from exposure to outcome. Learning objectives include defining prevention terms, understanding disease severity, prevention levels, and intervention measures. Studying disease prog

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Hannah, a vibrant young woman with a bustling social life and active routines, experiences a series of setbacks in her battle with Inflammatory Bowel Disease (IBD). Her journey highlights the importance of timely diagnosis, access to proper care, and comprehensive support services to manage the cond

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of analgesic, antipyretic, and anti-inflammatory medications that work by inhibiting prostaglandin synthesis. They provide relief from pain, reduce fever, and combat inflammation through various mechanisms. Aspirin, a commonly used NSAID, irr

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Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a diverse group of medications with analgesic, anti-inflammatory, and antipyretic properties. They act primarily on peripheral pain mechanisms and vary in their selectivity of COX inhibition. This article explores the history, classification, and se

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This informative content covers topics such as urethral catheterization, indications for catheterization, anatomic landmarks, male and female catheterization techniques, nosocomial UTIs, pelvic and breast examinations, breast cancer screening recommendations, and breast cancer statistics. It is a co

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Hereditary Connective Tissue Disorder, Hypermobile Ehlers-Danlos Syndrome (hEDS), and Mast Cell Activation Syndrome (MCAS) are three complex conditions with overlapping symptoms affecting collagen, joint laxity, and immune responses. Features associated with these conditions include joint pains, gas

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Chemical mediators of inflammation act on blood vessels and cells to contribute to an inflammatory response. These mediators include vasoactive amines like histamine and serotonin, plasma proteases such as the complement, kinin, and clotting systems, and important inflammatory mediators like C3a and

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Female reproductive system infections such as Pelvic Inflammatory Disease (PID), Vaginitis, Cervicitis, Endometritis, and Salpingitis can lead to various symptoms and complications. These conditions are caused by different factors including infections, bacterial imbalances, and sexually transmitted

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Bones and muscles of the pelvic limb, including the pelvis, thigh, leg, and foot, are detailed in this informative content. It covers the general designations of pelvic bones, descriptions of bones along with muscle attachments in various animals, and specifics about the hip bone structure and forma

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The instructor, Dr. Sanjay Kumar Bharti, explains the acetabulum, obturator foramen, sexual differences, and characteristics of sheep and goats related to pelvic anatomy. Details include the structure of the acetabulum, the large obturator foramen, pelvic cavity, and differences between male and fem

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The article discusses the anatomy of the acetabulum, obturator foramen, pelvic cavity, pelvic inlet and outlet, and sexual differences in the pelvis, with a focus on sheep and goats. It covers the structure of these pelvic components and highlights the variations between male and female anatomies. D

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In this educational content, we delve into the intricate details of acetabulum, obturator foramen, pelvic cavity, pelvic inlet and outlet, sexual differences, and anatomical variations in sheep and goats. The explanations are accompanied by informative images to aid in better comprehension.

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In a secondary analysis of the CANTOS study, researchers evaluated the impact of residual inflammatory risk and residual cholesterol risk in a large cohort of atherosclerosis patients already receiving lipid-lowering therapy. Results showed the relative contributions of inflammation and cholesterol

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Chemical mediators of inflammation play a pivotal role in inducing specific events during acute inflammation. These mediators are produced in response to various triggers, including microbial products and host proteins, leading to a cascade of inflammatory responses. Understanding the sources and ef

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Joint pain can result from various factors such as inflammation, cartilage degeneration, crystal deposition, infection, or trauma. Different pathophysiologic processes necessitate clinical evaluation and identification through history, physical examination, and understanding of joint disease types.

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Pelvic and paraaortic lymph node evaluation is crucial in the surgical staging of gynecological malignancies. The goals of lymph node dissection are to determine disease extent and guide further treatment. Pelvic lymph nodes include common iliac, external and internal iliac, obturator, sacral, and p

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Explore the expertise of Dr. Abdulaziz Alrabiah, MD in Emergency Medicine, Trauma & EMS through detailed images and descriptions of pelvic injuries, open fractures, and the Young Classification system. Enhance your knowledge on these critical aspects of trauma management.

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Non-steroidal anti-inflammatory drugs (NSAIDs) are a diverse group of medications with analgesic, anti-inflammatory, and antipyretic effects. They act primarily on peripheral pain mechanisms and have limited CNS effects. NSAIDs have a long history dating back to the use of White Willow bark, and the

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Dr. Margo Thienemann discusses the psychiatric medication management of a 10-year-old boy with inflammatory psychiatric disease, particularly focusing on Pediatric Acute-onset Neuropsychiatric Syndrome (PANS). The patient presented with various symptoms including compulsions, mood swings, OCD, oppos

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Explore the detailed anatomy and variations of the uterus, ovaries, fallopian tubes, and adnexa in pelvic ultrasonography. Learn about the different shapes and sizes of the uterus, layers of the uterine wall, and indications for pelvic ultrasound examination. Discover the significance of the appeara

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Patients with coronary artery disease should be screened for peripheral vascular disease as it is a frequent integrator of global cardiovascular risk. The association of atherosclerosis in various arterial diseases highlights the importance of identifying multisite artery disease. The prevalence and

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The Human Disease Symptom Network (HSDN) is constructed using a large-scale medical bibliographic records database to form a network of human diseases based on symptom similarities. By integrating disease-gene associations and protein-protein interaction data, correlations between symptom similarity

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Providing specialized physiotherapy support for mothers experiencing Obstetric Anal Sphincter Injuries (OASI) is crucial for addressing immediate problems like pain, urinary or fecal incontinence, and more. With a focus on pelvic health, this approach involves reassurance, tailored pelvic floor musc

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Cryptococcal Immune Reconstitution Inflammatory Syndrome (C-IRIS) is a condition where rapid reversal of immunodeficiency triggers exaggerated inflammatory reactions in response to Cryptococcus antigens. It can manifest as either Unmasking IRIS or Paradoxical IRIS, with common CNS presentations incl

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Explore the comprehensive overview of the anatomy of the pelvis, including its walls, bones, joints, muscles, and differentiations between male and female pelves. Learn about the boundaries, subdivisions, and pelvic floor components, as well as the arterial, nerve, lymph, and venous supplies. Delve

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Chlamydia and syphilis are common sexually transmitted infections that can have serious health consequences if left untreated. Chlamydia is often asymptomatic but can lead to complications like pelvic inflammatory disease in women. Syphilis presents with painless sores and can progress to affect the

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Lyme disease is an infectious inflammatory disease caused by Borrelia burgdorferi and spread by tick bites. It presents with a range of symptoms, including fever, headache, fatigue, and a characteristic erythema migrans rash. Prompt diagnosis and treatment are essential to prevent complications such

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Neisseria gonorrhoeae, also known as gonococcus, is a bacterial pathogen responsible for gonorrhea. The virulence factors of N. gonorrhoeae include pili/fimbriae for adhesion, outer membrane proteins like Porin for protection, opacity-associated protein for adhesion to neutrophils, and more. Clinica

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Pterygium, a common ocular surface lesion, has historically been considered degenerative due to factors like UV radiation exposure. However, recent research suggests an inflammatory component with cellular proliferative fibrosis and angiogenesis. This study presented at TOSCON 2024 delves into the h

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The inflammatory response is a crucial defense mechanism of the immune system. It comprises three lines of defense aimed at protecting the body from harmful pathogens. When a barrier is breached, such as by a splinter carrying bacteria, the inflammatory process is initiated. This includes the releas

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The female pelvis anatomy lecture covers the pelvic wall, bones, joints, and muscles. It explains the boundaries, subdivisions, and types of female pelvis, along with details on pelvic walls, floor, and diaphragm components. Additionally, it includes information on arterial, nerve, lymph, and venous

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A 57-year-old female presents to the emergency room with a large pelvic mass. Detailed history and physical examination are crucial, focusing on risk factors, past medical history, family history, medications, habits, and social factors. Along with vital signs and lymphadenopathy evaluation, a thoro

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Multiple sclerosis (MS) is a neurodegenerative disease affecting millions globally by causing myelin loss in the CNS axons. This study investigates the role of NF155 raft association in the inflammatory response of microglial cells, shedding light on potential treatment strategies for MS. Liposome t

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Inflammatory Bowel Disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC), chronic conditions with immunologic basis. This article delves into the epidemiology, pathophysiology, and differences between CD and UC, highlighting clinical features, pathology, and complications like a

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A 56-year-old male with a history of inflammatory bowel disease presented with severe symptoms necessitating hospitalization. Despite steroid therapy, lack of improvement led to consideration of a total colectomy. Colonoscopy and biopsy results favored ulcerative colitis over Crohn's disease. This c

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Inflammatory conditions of the heart, such as pericarditis and myocarditis, can have various causes and manifestations. Pericarditis can present as fibrinous, purulent, or hemorrhagic, each with distinct characteristics and implications. Myocarditis, on the other hand, can result from infections lik

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Pelvic floor dysfunction and prolapse are common issues affecting women, impacting their physical and emotional well-being. Surgical treatment may be necessary for symptomatic cases, but a thorough evaluation of symptoms, obstetric history, and other factors is crucial. Addressing precipitating fact

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The progression of periodontal disease can lead to bone destruction in the alveolar bone, which is crucial in supporting teeth. The inflammatory process causes permanent damage to the periodontium tissues, resulting in connective tissue loss and bone resorption. Different patterns of bone loss, such

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Mixed connective tissue disease (MCTD), also known as Sharp's syndrome, is a rare inflammatory rheumatic disease diagnosed through clinical evaluation, patient history, or special blood tests. Symptoms include overlapping connective tissue disease symptoms, with main cause being autoimmunity. It can

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This study examines the outcomes of parastomal hernia repair in patients with inflammatory bowel disease, specifically comparing outcomes between those with Crohn's disease and ulcerative colitis. The research, conducted from 2012 to 2022, analyzes data from 392 patients, highlighting factors such a

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