Cholestatic liver disease affects Alkaline Phosphatase (ALP) and bilirubin levels, indicating bile duct damage. GGT and 5'-Nucleotidase help differentiate hepatobiliary vs. bone origin of ALP elevation. ALP is produced by bile duct epithelium and can be normal in acute biliary obstruction. GGT and N

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Edit distance, a crucial concept in Computational Biology and NLP, measures the minimum number of operations needed to transform one string into another. It is widely used for tasks such as spell correction, aligning nucleotide sequences, evaluating machine translation, and speech recognition. By co

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Exploring the biosynthesis of purines and pyrimidines, essential components for DNA and RNA structures. Delve into the world of pyrimidines, purines, nucleosides, nucleotides, and adenosine derivatives like AMP, ADP, ATP, and cAMP, crucial for various biological processes. Unravel the significance o

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Gene translation from RNA to protein involves the specific binding of transfer RNA molecules to messenger RNA codons, enabling the translation of nucleotide sequences into amino acids. Each amino acid is attached to a specific tRNA through activating enzymes, and the anticodon on tRNA pairs with the

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Learn how to draw Watson-Crick base pairs accurately using ChemDraw software. Follow step-by-step instructions and visual aids to create base pairs and understand nucleotide structures effectively.

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Biological databases play a crucial role in bioinformatics, storing vast amounts of data related to nucleotide sequences, protein sequences, and more. These databases are publicly accessible and essential for research in biological fields. Primary databases, such as GenBank, EMBL, and DDBJ, contain

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DNA sequencing plays a vital role in various fields such as research, diagnostics, biotechnology, forensics, and biological systematics. By determining the order of nucleotide bases in a DNA molecule, it helps in understanding genetic sequences, identifying mutations, and completing projects like th

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A mutation in biology refers to changes in the nucleotide sequence of an organism's genome. These alterations can either be harmful, leading to conditions like cancer, or beneficial, such as providing antibiotic resistance. Mutations can occur in somatic cells or gametes, affecting both the individu

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DNA, or Deoxyribonucleic Acid, is a fundamental molecule in living organisms, characterized by its double helical structure consisting of two antiparallel polynucleotide chains. Each strand is composed of nucleotide monomers, comprising deoxyribose sugar, phosphate group, and nitrogenous bases (puri

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Delve into the world of nucleic acids with a focus on DNA and RNA molecules. Discover the fundamental building blocks, such as nucleotides, and the role they play in genetic information storage and cell function. Learn about the unique characteristics of DNA like its double-helix structure and the s

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Gene mutations are changes in the nucleotide sequence of DNA, leading to potential amino acid alterations in proteins. These mutations can occur due to replication errors or external factors like chemicals and radiation. Different types of mutations, such as base substitutions, transitions, transver

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Explore a thorough examination of gene expression and regulatory potential using eCLIP profiles, shRNA, RNA-Seq, secondary structure conservation, and prioritized genes. Uncover insights on users' variants, regulator scores, nucleotide scores, RBP rank lists, mutation burden, and more. Dive deep int

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Dan Jurafsky explains the concept of minimum edit distance as the minimum number of editing operations such as insertion, deletion, and substitution needed to transform one string into another. Through examples and visual representations, he illustrates how minimum edit distance plays a crucial role

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Delve into the world of genetics and ancestry analysis through SNPedia, a comprehensive resource for Single Nucleotide Polymorphisms (SNPs) information. Discover how Principle Component Analysis (PCA) simplifies genetic data to reveal insights into ancestry, traits, and informative SNPs. Explore exa

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This content provides detailed information on Cucumber Green Mottle Mosaic Virus, including its nucleotide genome, disease cycle, testing methods like DAS-ELISA and RT-PCR, seed testing protocols, bioassay for virus confirmation, and symptom expression in host plants. The data covers aspects such as

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Nucleotide Modifications Data Cards are vital primary research records that document raw data generated by SEA researchers. The checklist ensures accuracy and interpretability when analyzing restriction digest fragment patterns. Follow the instructions for obtaining genomic sequences and comparing v

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Genetic variation in human microRNAs indicates processes of positive selection and population-specific disease risks. The study explores miRNA diversity, transposable elements, nucleotide diversity, and population-specific SNP patterns. Insights into population genetics and disease susceptibility ar

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The Pentose Phosphate Pathway, also known as the Hexose Monophosphate shunt, is an alternative route for glucose metabolism that plays a crucial role in NADPH synthesis, fatty acid production, antioxidant activity, and nucleotide formation. This pathway involves oxidative and non-oxidative phases, r

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Explore the world of stereo images by learning how to view them in 3D using different techniques. Dive into molecular biology concepts such as DNA structure, nucleotide binding, and interactions with proteins through engaging visual aids and instructions. Enhance your understanding by identifying an

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DNA is a double helical structure made of 2 antiparallel polynucleotide chains with nucleotide monomers. The structure contains deoxyribose sugar, phosphate groups, and nitrogenous bases (purines and pyrimidines). Hydrogen bonds between base pairs stabilize the structure. Denaturation can occur due

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DNA, the genetic material of living organisms, consists of two antiparallel polynucleotide chains forming a double helical structure. Each chain is composed of nucleotide monomers, consisting of deoxyribose sugar, phosphate group, and nitrogenous bases (purines and pyrimidines). The backbone of DNA

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Discover the key aspects of DNA, including its structure as a nucleic acid polymer composed of nucleotides and the process of DNA replication. Learn about the double helix structure, base pairing rules, and the semi-conservative replication mechanism. Explore how DNA is synthesized in a 5 to 3 direc

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DNA, which stands for Deoxyribonucleic Acid, is a double-stranded molecule composed of nucleotides. Each nucleotide consists of a base, a phosphate, and deoxyribose sugar. These nucleotides bond together to form a sugar-phosphate backbone through chemical bonds. The DNA molecule contains four bases

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Obtain valuable insights into retrieving genome files for bioinformatics analysis utilizing multiple methods such as connecting via Finder, using Filezilla for FTP access, and executing curl commands on Xanadu. Learn how to access coding sequences, feature tables, nucleotide sequences, and encoded p

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This study delves into allelic bias in personal genomes, examining the influence of various factors such as sequencing datasets, removal of reads with allelic bias, and the impact on allele-specific single nucleotide variants (AS SNVs). The revised AlleleDB pipeline proposed includes steps for const

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DNA carries genetic instructions in organisms through nucleotide sequences like A, T, C, and G arranged in a double helix. Transcription converts DNA to mRNA in the nucleus, where RNA polymerase copies the DNA template. mRNA, with U instead of T, carries the genetic message. Translation involves ami

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Exploring the intricate world of DNA, this module delves into the structure of DNA, highlighting nucleotides, nitrogenous bases, and the double helix. It emphasizes how DNA stores genetic information in genes and undergoes replication through a semi-conservative model. The process of DNA replication

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Nucleic acids, including DNA and RNA, are fundamental molecules in all life forms, serving as hereditary determinants in cells. They are composed of nucleotide units, each containing a sugar, amine base, and phosphate group. The structure of DNA, with its double-stranded helix model, reveals specifi

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The process of Purine Nucleotide Synthesis involves the formation of purine ribonucleotides, breakdown into uric acid, and the detailed steps of purine nucleotide synthesis. Key components like IMP, SAICAR, PRPP, and ATP play crucial roles in this complex metabolic pathway, offering insights into th

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DNA and RNA are composed of nucleotides that form long chains called polynucleotides. Nucleotides consist of nitrogenous bases, pentoses (sugar molecules), and phosphate groups. The nitrogenous bases are derivatives of pyrimidine and purine compounds, with DNA containing adenine (A), guanine (G), cy

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The central dogma in molecular biology explains the flow of genetic information from DNA to RNA to protein through transcription and translation. The genetic code is a set of rules translating nucleotide sequences into amino acids. It consists of codons that specify amino acids, with sense and signa

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