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Lipoprotein and Atherosclerosis

Understand the correlation between lipoprotein metabolism imbalance and the development of atherosclerosis. Learn about LDL and HDL cholesterol metabolism, receptor-mediated endocytosis, and the role of lipoprotein(a).

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Inflammation and Cholesterol Predicting Cardiovascular Events

This study explores how inflammation and cholesterol levels predict cardiovascular events among 13,970 statin-intolerant patients in the CLEAR Outcomes trial. Findings suggest residual inflammatory risk may be a stronger predictor than residual cholesterol risk for future events. The research analyz

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The REPRIEVE Trial: Developing Cardiovascular Disease Prevention Strategy for People Living with HIV

The REPRIEVE trial focuses on developing a cardiovascular disease prevention strategy for individuals living with HIV. It addresses the increased risk of CVD in this population, even with good viral suppression. The study evaluates the use of pitavastatin, a statin with anti-inflammatory properties,

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CLEAR Outcomes Trial: Bempedoic Acid for Cardiovascular Prevention

The CLEAR Outcomes Trial investigated the effects of bempedoic acid, an ATP citrate lyase inhibitor, on cardiovascular outcomes in primary prevention patients. Results showed a reduction in cardiovascular events with bempedoic acid, particularly in patients intolerant to statins. Baseline characteri

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Impact of Diet on Cardiovascular Health

The impact of diet on the cardiovascular system is significant, with a high intake of LDL leading to clogged arteries and increased risk of Coronary Heart Disease. Regular exercise brings about positive changes in the cardiovascular system, enhancing heart function and oxygen delivery. Immediate ben

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Understanding Lipoproteins: Structures and Functions

Lipoproteins are compound lipids formed by the aggregation of neutral and amphipathic lipids with proteins (apoproteins). They serve as vehicles for transporting lipids through the bloodstream and lymphatic system, acquiring polarity due to their hydrophilic properties. These macromolecules are synt

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Optimal Management of Lipids for Secondary Prevention Team Study

Lipid management in secondary prevention plays a crucial role in reducing cardiovascular risk. This study led by Dr. Timir Paul aims to address system-level gaps in care, enhance communication for optimal therapy, and empower patients in achieving target lipid levels. By recognizing disparities and

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Understanding Cholesterol and Its Impact on Health

Cholesterol is essential for bodily functions but too much of it can lead to health issues. LDL cholesterol is known as "bad" cholesterol, while HDL cholesterol is considered "good". High cholesterol levels can increase the risk of heart disease and stroke. Managing cholesterol through diet, weight

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