Cholestatic liver disease affects Alkaline Phosphatase (ALP) and bilirubin levels, indicating bile duct damage. GGT and 5'-Nucleotidase help differentiate hepatobiliary vs. bone origin of ALP elevation. ALP is produced by bile duct epithelium and can be normal in acute biliary obstruction. GGT and N

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Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare blood disorder characterized by the destruction of red blood cells in the bloodstream, leading to anemia, hemoglobinuria, jaundice, and other symptoms. It is often challenging to diagnose due to its rarity. PNH can be a thrombophilic state, causing

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Neonatal jaundice, a common condition in newborns, results from elevated bilirubin levels. While often benign, high levels can lead to complications like kernicterus. Recognizing risk factors, limitations of clinical assessment, and appropriate evaluation and treatment are crucial in managing neonat

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Liver disorders can profoundly impact your well-being, resulting in fatigue, weight loss, and jaundice. In severe cases, they may even prove fatal. If you suspect any symptoms, it\u2019s crucial to promptly consult Dr S. Srivatsan Gurumurthy for Liver Disease Treatment in Chennai. Timely medical att

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Cholestasis is characterized by reduced bile flow and elevated direct bilirubin. It is critical to differentiate it from neonatal jaundice. In conditions like biliary atresia and 1-antitrypsin deficiency, early diagnosis and intervention are crucial to prevent liver failure. Clinical manifestations

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Explore the detailed information about bilirubin metabolism and various types of jaundice, including their clinical presentations, etiologies, and management strategies. Learn to differentiate between different types of jaundice based on case scenarios and understand the functional anatomy and physi

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This clinical case study focuses on a pediatric patient presenting with abdominal enlargement and a history of delayed development. Key aspects covered include birth and maternal history, immediate postnatal course, developmental milestones, and past medical history. The diagnosis process involves c

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This educational content delves into hyperbilirubinemia, focusing on its definition, causes, metabolic processes, associated complications, and treatment options like phototherapy and exchange blood transfusion. Key topics covered include physiologic jaundice, the seriousness of unconjugated bilirub

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Bilirubin, a yellow compound in the catabolic pathway, plays a crucial role in health. Estimating serum bilirubin levels is key in diagnosing conditions like jaundice. Elevated levels, above 2 mg/dl, can indicate disease. Jaundice, characterized by skin and eye discoloration, has pre-hepatic, hepati

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Bovine theileriosis is a tick-borne haemoprotozoan disease that causes significant economic losses in livestock due to high mortality rates, weight loss, abortion, and reduced milk yield. The disease is characterized by fever, anemia, and respiratory and digestive disorders. It is caused by parasite

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Choledocholithiasis, the presence of stones in the common bile duct, is a common condition found in a percentage of patients with gallstones. The stones can be primary or secondary, causing a range of clinical manifestations from silent obstruction to cholangitis or gallstone pancreatitis. Diagnosis

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Anemia in swine can be caused by factors such as gastric ulcers, internal bleeding, and poor nutrition. Clinical signs include pale skin, rapid breathing, and jaundice. Piglet anemia, a highly fatal disease, is marked by decreased hemoglobin levels and liver degeneration. Diagnosis involves examinin

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This presentation by Dr. Khalid Altirkawi, M.D., Assistant Professor of Pediatrics, aims to educate medical students on neonatal jaundice. The content covers metabolic pathways of bilirubin, types of jaundice, diagnostic tests, prevention, and treatment strategies. It provides valuable insights into

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Choledochal cysts are congenital anomalies of the biliary tract characterized by cystic dilatation at various segments. They can lead to complications like biliary cirrhosis and recurrent pancreatitis. Clinical features include jaundice, abdominal pain, and right epigastric mass. Early detection is

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Yogic science explores the impact of yoga on various diseases like asthma and jaundice. For asthma, specific yoga poses and breathing techniques can help improve respiratory function and reduce symptoms. On the other hand, jaundice, characterized by yellowing of the skin, can also benefit from yoga

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Ascites, jaundice, and confusion in a 50-year-old man raise concerns about liver disease. Differential diagnosis includes cirrhosis, malignancy, alcoholic liver disease, and biliary obstruction. Physical examination findings such as spider naevi, hepatomegaly, and asterixis help narrow down the poss

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This presentation by Dr. Amr Ahmed Hamed, a lecturer at Sohag University, explores various fever associations and clinical presentations related to tropical medicine and gastroenterology. Topics covered include fever with jaundice, sweating, rigors, hepatomegaly, splenomegaly, rash, lymphadenopathy,

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Viral hepatitis is caused by various hepatotropic viruses, including Hepatitis A, B, C, D, and E. This type of liver inflammation can manifest acutely or chronically, leading to symptoms such as jaundice, abdominal pain, nausea, and fatigue. Hepatitis A virus, in particular, is primarily transmitted

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Hepatobiliary and pancreatic disorders can lead to conditions like jaundice, caused by an accumulation of bilirubin. Jaundice can be classified as prehepatic, intrahepatic, or posthepatic depending on the underlying causes such as liver damage, hepatitis, cirrhosis, or bile duct obstructions. Liver

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Smooth Endoplasmic Reticulum (SER) is a vital organelle involved in various cellular functions such as synthesizing phospholipids, detoxifying drugs, producing hormones, and aiding in lipid metabolism. Its role in processing bilirubin helps prevent jaundice, with implications for newborn health. The

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Tick fever in neonates is a febrile disease transmitted by tick bites, with symptoms including fever, loss of appetite, depression, weakness, red urine, anemia, and jaundice. The disease can be diagnosed through clinical symptoms, tick presence, and blood smear examination. Treatment involves medica

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This presentation discusses the principles, causes, presentations, management, and prognosis of acute liver disorders, with a focus on insult to the normal liver leading to liver injury, inflammation, and necrosis. It covers causes such as drugs, viruses, ischemia, autoimmune conditions, Budd-Chiari

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Acute liver disorders can have various causes such as drugs, viruses, ischemia, autoimmune conditions, and more. The presentations of acute liver disease can include abnormal liver tests, jaundice, liver impairment, and even liver failure. Management involves removing and treating the underlying cau

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Acute liver failure is a severe condition characterized by rapid liver dysfunction within 6 months of symptom onset, leading to encephalopathy, coagulopathy, and jaundice. This condition can be classified as hyperacute, acute, subacute, fulminant, or sub-fulminant based on the duration from jaundice

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A three-day-old infant presenting with not passing meconium, abdominal distension, lethargy, decreased feeding, and jaundice is evaluated for possible pediatric surgical issues. Conditions such as duodenal atresia, imperforate anus, and intussusception are discussed along with their diagnostic and m

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An 8-year-old boy presents with intermittent abdominal pain that occurs before breakfast and sometimes at school, relieved by activities. He also exhibits jaundice and abnormal liver function tests, indicating a potential underlying liver issue. Immediate medical evaluation is necessary to diagnose

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Serum bilirubin levels are crucial in diagnosing conditions like jaundice, with total, direct, and indirect bilirubin playing key roles. Excess bilirubin in the blood can lead to jaundice, characterized by yellow discoloration of the skin and eyes. Different types of jaundice, including pre-hepatic,

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