The caste system in India is a social structure defined by hereditary groups, each with specific occupations, rules, and traditions. Membership is based on birth, leading to a rigid hierarchy and limited mobility between castes. Endogamy, occupation, commensality, and purity are key features that sh

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Immune deficiencies can be classified into primary hereditary disorders based on clinical presentations, including cell-mediated, antibody-mediated, non-specific, and complement activation deficiencies. Major clinical manifestations of immune disorders range from B-cell deficiencies to phagocytic ce

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Sickle cell trait is a hereditary condition affecting red blood cells' shape and oxygen-carrying capacity. Individuals with this trait can experience complications during intense exercise, leading to health risks in athletics. This article explores the impact of sickle cell trait on athletes, the re

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Consultant Clinical Geneticists play a crucial role in assessing the risk of high-risk hereditary cancer predisposition, implementing prevention strategies, and early detection through methods like Whole Body MRI. Surveillance involves annual examinations, imaging, and expert coordination between cl

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Hereditary Connective Tissue Disorder, Hypermobile Ehlers-Danlos Syndrome (hEDS), and Mast Cell Activation Syndrome (MCAS) are three complex conditions with overlapping symptoms affecting collagen, joint laxity, and immune responses. Features associated with these conditions include joint pains, gas

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The executive branch of government is responsible for implementing and enforcing laws created by the legislative branch. There are different types of executives, including nominal/real, single/plural, and hereditary/elected. The distinction between these types is crucial in defining the roles and re

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Politics is the social institution responsible for power distribution, goal-setting, and decision-making in society. Every society is built on power, with government being the formal organization that directs political life. Governments strive to establish authority perceived as legitimate by the pe

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Heterotopic ossification (HO) is a phenomenon where bone forms in soft tissues outside the skeletal system. Initially observed in children with myositis ossificans progressiva, HO has been linked to trauma, neurogenic factors, and hereditary conditions like myositis ossificans progressiva. Clinicall

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Testicular hypoplasia and degeneration are conditions affecting the development and function of the testes in animals, particularly bulls. Hereditary and non-hereditary forms exist, leading to partial or complete failure in spermatogenic epithelium development. The incidence is low and sporadic, mor

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Mutation is a sudden hereditary change in an organism's genetic makeup, leading to variations in offspring. This article delves into the history, types, and causes of mutations, featuring significant discoveries by scientists like De Vries and Morgan. It also explores the concept of spontaneous muta

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Nephritis is a serious medical condition characterized by inflammation of the nephrons in the kidneys. This inflammation can lead to various subtypes such as glomerulonephritis and interstitial nephritis, each with its own causes and symptoms. Common symptoms of nephritis include edema, changes in u

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Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor that requires specialized management. This comprehensive guide covers the clinical presentation, diagnosis, genetic aspects, and detailed management strategies for MTC, including surgical options, follow-up evaluation, and systemic the

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Autopsy, also known as necropsy or postmortem examination, is a vital procedure that provides valuable insights into the cause of death, diseases, hereditary conditions, and legal matters. This practice dates back to ancient civilizations like the Egyptians. By conducting autopsies, medical professi

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Unwanted materials can be passed directly or indirectly, impacting the complexity of systems and bodies. Reproduction methods include sexual and asexual, each with unique processes and characteristics. Asexual reproduction involves division and growth, while sexual reproduction combines hereditary i

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DNA, the hereditary basis of life, was first discovered by Friedrich Miescher in 1869. It consists of chromosomes, plasmids, and organellar DNA, collectively known as the genome. Genes, sequences of DNA, encode proteins and RNA, essential for an organism's functions. The genome is divided into chrom

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Genetic material plays a crucial role in the transmission of traits from one generation to the next. This article explores the significance of DNA and RNA as genetic material, highlighting key experiments and discoveries that demonstrate DNA's role in carrying hereditary information. From Mendel's h

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Genetics encompasses the study of chromosomes, genes, and inheritance patterns. Chromosomes are bar-like structures carrying DNA, with homologous pairs determining traits. Autosomes and sex chromosomes play roles in genetic makeup. Genes are hereditary units determining individual traits, with allel

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Basic immunological terms explain the functions of the immune system, including defense against infection, homeostasis, and immunological surveillance. Immunodeficiencies are disorders of the immune system that impair its ability to carry out these functions. They can be classified into humoral, cel

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Arthritis is inflammation of joints causing pain and limited function. It can be due to injury, metabolic abnormalities, hereditary factors, infections, or autoimmune conditions. Types include Osteoarthritis, Rheumatoid Arthritis, Gout, Ankylosing Spondylitis, Psoriatic Arthritis, and Reactive Arthr

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Delve into the world of juvenile hallux valgus, a condition affecting the alignment of the big toe in children. Learn about its different forms based on age groups, associated anatomical features, pathoanatomy, soft tissue, and bony deformities. Discover the hereditary and syndromic links, diagnosti

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Exploring simple heredity through predicting and modeling phenotypes of Crazy Creatures, students are tasked with contrasting genotype and phenotype. The Crazy Traits lab data table is essential for recording alleles and genotypes, aiding in determining phenotypes for 14 different traits. By complet

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Gregor Mendel, a father monk in the 1800s, conducted groundbreaking research on how traits are inherited through plants, laying the foundation for modern genetics. Despite initial lack of recognition, his work on pea plants led to the discovery of genetic factors and the understanding of hereditary

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Molecular biology delves into the study of biology at the molecular level, focusing on gene structure and functions to comprehend hereditary traits, genetic variation, and gene expression patterns. Cells, the fundamental units of life, vary in shape and function but share basic structures. The Three

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The Shang and Zhou dynasties in ancient China were characterized by the rule of kings who held political, religious, and military power. The Shang rulers expanded their territories with the help of warlords and aristocrats, while the Zhou dynasty instituted hereditary aristocratic rule. Chinese soci

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Explore the fascinating world of genetics through the scientific study of heredity and the groundbreaking work of Gregor Mendel, the Father of Genetics. Learn about hereditary traits, the role of fertilization, Mendel's experiments with pea plants, and the concepts of genes and alleles that shape bi

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Haemolytic anaemias result from increased red cell destruction, involving normal red cell breakdown processes like extravascular removal by macrophages. This breakdown leads to the liberation of iron, bilirubin circulation, and protein synthesis. An introduction to haemolytic anaemias explains how t

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The Permanent Settlement introduced by Lord Cornwallis in 1793 empowered zamindars to collect revenue, causing peasants to become tenants. While it provided security, it led to various issues such as high land revenue, conflicts, and hereditary landlords. The system failed to satisfy the British, za

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Delve into the mysteries of the early Earth and the origin of life through engaging categories such as the absence of certain gases in the atmosphere, the synthesis of amino acids in lab simulations, the formation of protocells using DNA, and the bombardment of space debris. Discover how reducing at

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Exploring cancer predisposition syndromes, basic genetics, and vocabulary related to pediatric cancer risk factors. Topics include CNS tumors, solid tumors, leukemia, hereditary retinoblastoma, and genetic testing guidelines for children with cancer predispositions.

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The elbow joint is a true diathrodial joint formed by the articulation of various structures. Disorders such as elbow luxation, un-united anconeal process, and fragmented coronoid process can lead to lameness and other clinical signs in animals. Causes include osteochondritis dissecans and trauma, w

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Phenotypic and genotypic variations in bacteria are crucial for their adaptation and survival. Phenotype reflects the physical expression influenced by both the genome and the environment, while genotype represents the hereditary constitution passed to offspring. Mutations are a primary source of ge

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SVA retroelement insertions, specifically SINE-VNTR-ALU (SVA) types, were examined through Next Generation Sequencing (NGS) and RNA analysis in hereditary cancer panel testing. Twelve unique SVA retroelements were identified in genes like APC, BRCA1, CHEK2, and others, with variant interpretations r

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Nucleic acids, including DNA and RNA, are fundamental molecules in all life forms, serving as hereditary determinants in cells. They are composed of nucleotide units, each containing a sugar, amine base, and phosphate group. The structure of DNA, with its double-stranded helix model, reveals specifi

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