Explore the genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition, tracing the evolution of hominins over the last 4 million years, and studying essential events in the emergence of humans in the last one million years. Discover well-known human population

4 views • 33 slides

The genomic medicine field is advancing rapidly, with a focus on enhancing healthcare services through genomic testing for prediction, prevention, diagnosis, and precision medicine. The NHS is actively integrating genomics into its healthcare system, aiming for equitable access to genomic testing. I

1 views • 16 slides

An update on the progress of various infrastructure projects in the Annual Performance Plan is provided, covering categories such as Community-Based Tourism Projects, Maintenance of Provincial Tourism Assets, and Tourism Infrastructure Projects. The report includes details on the implementation stat

2 views • 17 slides

Evolving 5030 District Projects aims to enhance leverage, visibility, and scale for club projects and beneficiaries. Current initiatives include Harvest Against Hunger, Music4Life, Music Mends Minds, and Partners for Work, among others. The District Policies outline the criteria for establishing and

3 views • 11 slides

Lujia Chen, a Postdoc Associate at the University of Pittsburgh, focuses on developing deep learning models for precision oncology. By utilizing machine learning, especially deep learning models, Chen aims to identify cancer signaling pathways, predict drug sensitivities, and personalize cancer trea

1 views • 5 slides

In this lab activity, students will learn how to isolate genomic DNA from arthropods and Wolbachia bacteria. The goal is to transition from fieldwork to molecular biology, utilizing DNA as a diagnostic tool. The activity involves extracting total genomic DNA from identified species and includes pre-

0 views • 11 slides

This case involves a 2-month-old female with Tetralogy of Fallot, carrying a genetic variation in the 19p13.11 region. The evaluation process includes assessing genes, known dosage sensitivity, gene count, and detailed analysis of the duplication found in the DGV Gold Standard Dataset. The frequency

0 views • 17 slides

The report highlights current challenges and identified gaps in genetic and genomic testing for breast cancer risk assessment. The workgroup aims to catalog existing materials, address terminology confusion, and improve public and clinician education. Challenges include complex terminology, uncertai

0 views • 21 slides

This trial aims to compare the efficacy and safety of molecularly-guided therapy or cancer immunotherapy based on genomic profiling with platinum-based chemotherapy in patients with cancer of unknown primary site. The study design includes multiple treatment regimens guided by genomic profiles, with

4 views • 9 slides

Developed by Genomics Education Programme, these slides focus on the patient choice consent model for whole genome sequencing in NHS Genomic Medicine Service. The model aims to ensure informed choices for genomic testing, including participation in the National Genomic Research Library. It covers se

0 views • 34 slides

Providing information on discontinued and current tourism infrastructure projects, the presentation outlines the purpose, funding sources, and status of various projects. While some projects have faced challenges leading to discontinuation, a significant number are actively being implemented, primar

0 views • 28 slides

This conversation with Dr. Samantha Evans, Director of Evaluation at Genome Canada, delves into the importance of program evaluation in genomic science. Genome Canada aims to connect ideas, invest in science and technology, and maximize impacts across sectors. The evaluation process involves collect

0 views • 36 slides

The Partnering with Industry Symposium in February 2022 presented valuable insights into major capital projects like the Interdisciplinary Science and Innovation Centre (ISIC), Capital Maintenance, Utility Reduction Programs, and Minor Institutional Projects. Specifics of projects such as ISIC's 9,5

0 views • 8 slides

The NEP workshop on Off-Grid Electrification in Myanmar held in Nay Pyi Taw in 2015 shed light on various off-grid hydropower projects in different states of Myanmar. The projects range from small-scale individual setups to larger community-based initiatives, showcasing a mix of private, government-

0 views • 44 slides

Explore the intricate details of cancer treatment through precision oncology, focusing on cell of origin, genomic changes, tumor microenvironment, host factors, and response to various treatments such as chemotherapy, biological therapy, and immune therapy. The natural history and histology-guided c

0 views • 9 slides

Explore the concept of ridge regression in genomic selection, involving the development of genomic selection methods, pioneers in implementation, fixed and random effects, and the over-fitting phenomenon. Learn how ridge regression addresses issues of over-fitting by introducing regularization param

0 views • 26 slides

Keyport School District is planning various capital projects across its schools including facility upgrades, asbestos abatement, plumbing, and field improvements. The total cost for the proposed projects is over $9.8 million. Key projects include boiler replacements, classroom upgrades, gym renovati

0 views • 11 slides

The Fusion Science Department Enabling Research Projects for 2021-2023 focus on developing novel fusion-relevant scientific and technological ideas. These projects, led by Principal Investigators, are distinct from main work packages and involve scientific planning, team collaboration, and resource

0 views • 11 slides

The study explores the intricate relationship between genetic and regulatory codes that shape protein evolution. Discusses how duons, genomic footprints, and transcription factors densely populate and constrain protein-coding exons. Highlights how regulatory elements influence codon choice independe

0 views • 21 slides

Explore the intricate world of gene regulation and genomic data analysis through a comprehensive study presented at a faculty workshop in 2014. Delve into the evolution and classification of biology, the impact of genome sequencing on digitizing biology, and the potential of genetic information vari

0 views • 18 slides

The review of the implementation of Smart Cities Mission in Kota, Rajasthan as of 24-03-2017 highlights the appointment of human resources, funds allocation, progress of ongoing projects, tendered projects, preparation of upcoming projects like Lake Development and Solar Master Plan, as well as visi

0 views • 26 slides

This toolkit provides essential resources for healthcare professionals involved in genomics services, covering topics such as genomic medicine, whole genome sequencing, clinical genetic testing methods, interpretation of DNA variants, and more. It also details the specific sample requirements for di

0 views • 24 slides

Genome projects generate large GFF files which require significant storage space. GPress offers a solution by compressing GFF files while allowing quick searches and random access. The framework addresses challenges faced by current GFF utilities, providing a more efficient approach to managing and

0 views • 24 slides

This detailed report examines the technology projects backlog process, project trends, and analysis of completed projects within the past year. It delves into metrics such as active projects, completed projects, new projects, and the ratio of incoming requests to completed projects. Additionally, it

0 views • 4 slides

Genomic selection in dairy cattle focuses on specialized breeds like Holstein, Jersey, Brown Swiss, and Ayrshire. It brings reliable breeding values at a young age, higher success rates in obtaining top bulls, and lower costs for test proofs, leading to a shorter generation interval. While it offers

0 views • 12 slides

The Boating Infrastructure Grant (BIG) Program by the California State Parks Division of Boating & Waterways aims to provide funding for boating-related projects. From Tier I projects with grants up to $200,000 to Tier II projects up to $1.5 million, the program supports various activities like tie-

0 views • 9 slides

This study discusses the inclusion of feed intake data from U.S. Holsteins in genomic prediction, focusing on residual feed intake (RFI) as a new trait. The research involves data from research herds and genotypes of cows, with genetic evaluation models and genomic evaluation for predicting feed int

0 views • 17 slides

This document outlines a genomic imputation pipeline for multiple GWAS studies using reference panels such as 1000 Genomes Phase I data. It covers steps like data matching, phasing, and imputation using tools like Beagle and Minimac. The expected output includes imputed dosages and quality measures.

0 views • 6 slides

Clinical assessment was conducted on a 4-month-old male with bilateral microphthalmia due to a genomic deletion in the 13q12.11 region. The deletion encompasses part of a protein-coding gene and has been associated with various birth defects and developmental delays in previous cases. Detailed evalu

0 views • 13 slides

BED (Browser Extensible Data) files are commonly used for annotating genomic sequences by specifying ranges on chromosomes. They consist of required fields like chromosome name, start and end positions, and optional fields for additional information such as name, score, strand, and color representat

0 views • 11 slides

Explore the application of genomic recursions in single-step genomic best linear unbiased predictor (BLUP) for genetic evaluations in animal breeding. Understand the significance of using genomic data to improve genetic selection, increase accuracy, shorten generation intervals, and enhance genetic

0 views • 31 slides

The Fiscal Year 2023 Indian Housing Block Grant (IHBG) Competitive NOFO Training focuses on Soundness of Approach with a maximum of 42 points. Subfactor 3.1 emphasizes IHBG Competitive Priorities, including new housing construction projects, housing rehabilitation projects, acquisition of units, and

0 views • 23 slides

The Mainstreaming Genomic Medicine post provides insights into the background and progress of the 100,000 Genomes Project, including details on genetic vs. genomic testing, the setup of NHS Genomic Medicine Centres, types of cancer included, and samples taken. It covers the project's inception, key

0 views • 19 slides

The Hacienda La Puente Unified School District has completed several school site improvement projects and provided updates on projects in progress as of October 27, 2022. Completed projects include upgrades to facilities such as carpeting, lighting, and turf at various school sites. The district is

0 views • 11 slides

This genetic case study involves a 10-year-old female with a de novo 17p13.3 deletion, presenting with mild intellectual disability and growth delay. The deletion overlaps with the Miller-Dieker syndrome critical region, impacting genes associated with lissencephaly and cognitive impairment. Through

0 views • 19 slides

Mainstreaming in healthcare involves shifting genomic testing from Clinical Genetics to various specialties, such as cancer MDTs. This process impacts consent for genetic testing and result communication. NDRS data analyzes the time to diagnosis, while training and resources focus on why mainstreami

0 views • 7 slides

In 2021, the RCM Team experienced several updates and achievements, including team members transitioning to new roles, completing rotations, passing professional exams, and welcoming new members. The team managed a portfolio of 108 projects, with over 100 new projects received and 47 projects closed

0 views • 10 slides

This presentation delves into the concept development and implementation of ridge regression in genomic selection, emphasizing the importance of avoiding overfitting by regulating parameters and distinguishing between fixed and random effects. The pioneers of ridge regression and Bayesian methods ar

0 views • 26 slides

Evaluated requests for 15 proposal renewals, reviewed Excellence in Multistate nominations, assigned lead reviewers to projects, began review of new proposals, conducted mid-term reviews, voted on rule changes, reviewed guidelines, reviewed membership, and discussed various projects transitioning in

0 views • 8 slides

Genome browsers are essential tools for visualizing complex genome information, integrating sequence data with annotations in a user-friendly graphical interface. They enable exploration of chromosomal regions, regulatory elements, and comparative genomics across different organisms. Key examples in

0 views • 24 slides