Drug dosing - PowerPoint PPT Presentation


Age-Friendly App: Managing Drug-Drug Interactions Between Prescriptions and OTC Analgesics

The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

1 views • 25 slides


Understanding Posology in Pharmacology: Factors Affecting Drug Dosage

Posology, the science of determining drug dosage, is influenced by various factors including age, sex, body weight, route of administration, and more. Changes in pharmacokinetics with age, differing drug responses in men and women, and the importance of body weight in dosing are crucial consideratio

6 views • 23 slides



Understanding Aminoglycoside Antibiotics and Dosing Strategies

Aminoglycoside antibiotics are potent but require precise dosing due to variability among patients. Suggested dosing adjustments based on serum concentrations can ensure therapeutic levels without toxicity. Various methods, like linear pharmacokinetics, individualized dosing, and computerized progra

16 views • 71 slides


Understanding Regulatory Requirements of Drugs and Pharmaceuticals

Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

0 views • 28 slides


Polymeric Controlled Drug Delivery Systems

Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

0 views • 33 slides


Renal Pharmacology: Drug Excretion and Renal Clearance Questions

This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

0 views • 55 slides


Understanding Nasopulmonary Drug Delivery System

Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

0 views • 35 slides


Digoxin Pharmacokinetics and Clinical Considerations

This presentation covers the pharmacokinetic parameters, dosing guidelines, therapeutic and toxic concentrations, and factors affecting digoxin clearance and distribution. It explores how digoxin clearance is linked to creatinine clearance, usual dosing regimens for adult patients, and disease state

0 views • 41 slides


Understanding Physicochemical Properties of Drugs

The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

1 views • 46 slides


Understanding Formulary Systems in Healthcare

A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

0 views • 17 slides


Ways to Stay Drug Free: Lessons for Teens and Families

Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

0 views • 17 slides


Understanding the Hatch-Waxman Act: Promoting Affordable Generic Drugs

The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

0 views • 49 slides


Understanding Therapeutic Drug Monitoring and Clinical Pharmacokinetic Parameters

Therapeutic Drug Monitoring (TDM) utilizes pharmacokinetic principles to optimize drug therapy by balancing efficacy and toxicity levels. Historical background reveals a shift from empirical dosing to precise pharmacokinetic analysis, aiming to minimize toxicity risks and maximize therapeutic benefi

0 views • 47 slides


Understanding Biopharmaceutics: pH Partition Theory and Drug Absorption

Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

0 views • 9 slides


Importance of In-Vitro Dissolution Testing in Drug Assessment

In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

10 views • 10 slides


Clinical Pharmacy Laboratory DM and Insulin Dosing Regimens

This comprehensive content covers various insulin dosing regimens used in clinical pharmacy laboratories for patients with diabetes mellitus. It includes examples of dosing regimens before meals and at bedtime, methods of insulin administration, vial images, mixing of different types of insulin, and

0 views • 14 slides


Understanding Pharmacodynamics: Potency and Efficacy

Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

0 views • 21 slides


Understanding Drug Absorption, Excretion, and Bioavailability in Humans

Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

0 views • 24 slides


Understanding Quantitative Aspects of Drug Action

Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

0 views • 29 slides


Review of DRE School and Drug Evaluation Techniques

Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like

0 views • 29 slides


Study on Juvenile Drug Crime Prevention in Taiwan: Insights from ACS Conference 2020

This presentation at the Asian Criminological Society Conference 2020 delves into the current situation, dilemmas, and responses regarding juvenile drug crime prevention in Taiwan. The presenter, Zeng Li-Wen, a PhD student at Central Police University in Taiwan, provides valuable insights based on t

0 views • 20 slides


Understanding Drug Abuse: Definitions, Effects, and Stages

Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.

4 views • 45 slides


Understanding Drug Targets and Mechanisms of Action

Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o

3 views • 17 slides


International Day Against Drug Abuse and Illicit Trafficking 2022 Initiatives and Awareness

The United Nations observes 26th June as the International Day Against Drug Abuse and Illicit Trafficking to combat substance abuse worldwide. Various initiatives like the National Drug Master Plan, Nasha Mukt Bharat Abhiyaan, and the National Action Plan for Drug Demand Reduction aim to raise aware

3 views • 9 slides


Principles of Pharmacy Practice - Drug Dosing Guidelines and Measurements

Understanding drug dosing is crucial in pharmacy practice. This lecture covers various aspects of doses, including adult and pediatric doses, dosage regimens, median effective and toxic doses, loading and maintenance doses, and prophylactic and therapeutic doses. Dose measurements in institutional s

0 views • 16 slides


Genotype-Directed Dosing for Efavirenz in Children Study

The study focuses on genotype-directed dosing of Efavirenz in children with HIV, aiming to optimize treatment options and dosages based on genetic factors. It explores the challenges in treating children with HIV, especially in resource-limited settings, and discusses the impact of genetic variation

0 views • 21 slides


Comprehensive Review of Drugs, Categories, and Drug Influence Evaluation

This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru

0 views • 28 slides


Nordic Prescription Registers in Iceland: Overview and Coverage

The Nordic Prescription Registers in Iceland provide detailed data on prescription drug dispensing, covering variables such as drug user information, dispensing details, prescriber data, pharmacy information, and more. The database includes information on all reimbursed and non-reimbursed prescripti

0 views • 11 slides


Optimizing Antibiotic Therapy for Pathogenic Bacteria and Resistance

Understanding the pharmacokinetic/pharmacodynamic relationships in antibiotic therapy is crucial for maximizing effectiveness against bacteria while minimizing resistance. Different bacterial loads and stages of infection require tailored dosing regimens to achieve optimal outcomes. Monitoring antim

0 views • 35 slides


Impact of Socioeconomic Conditions on Drug Use Disorders: Insights from World Drug Report 2020

The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

0 views • 17 slides


Comparing Efficacy of LPV/r QD vs. BID in Combination Therapy

Study M02-418 compared once-daily (QD) and twice-daily (BID) LPV/r in combination with TDF and FTC for HIV treatment. The primary endpoint was achieving HIV RNA <50 c/mL at week 48, aiming for non-inferiority of QD vs. BID dosing. Patient characteristics, treatment response at week 48, and pharmacok

0 views • 7 slides


Pediatric Endocrinology Insulin Dosing Guide

Comprehensive reference for insulin dosing in pediatric endocrinology, covering onset, peak, and duration of action of various insulin preparations, guidelines for twice-daily dosing, managing Dawn Phenomenon and rebound hyperglycemia, and tips for multiple daily injections. Includes information on

0 views • 13 slides


Understanding Targeted Clinical Investigation in Pharmacovigilance

Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

0 views • 12 slides


Pediatric Pharmacology Considerations and Challenges

Developmental pharmacology in children involves unique considerations such as drug metabolism, urine concentration, and muscle relaxant dosing. The field faces challenges with limited drug testing in pediatric populations, emphasizing the importance of age-appropriate pharmacotherapy. Factors like d

0 views • 39 slides


Advances in Ophthalmic Drug Delivery Systems

This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

0 views • 8 slides


Transition from Prothrombinex-VF to Beriplex: Information and Guidance

In mid-2024, Prothrombinex-VF will be replaced by Beriplex, with the transition occurring in two stages. Beriplex P/N will be interim until Beriplex AU is available, with identical compositions. Clinicians are provided with dosing guidance for Beriplex, and the WA Anticoagulation Chart has been upda

0 views • 7 slides


State Responsible Inmates with Marijuana Convictions Research Report

Research conducted by VADOC indicates a total of 570 state responsible inmates incarcerated for marijuana-related offenses as of August 31, 2021. Among them, 229 inmates had non-drug-related Most Serious Offenses, 331 were convicted for Drug Sales MSO, and 10 were convicted for Drug Possession MSO.

0 views • 7 slides


Innovative Online Learning for Drug Court Professionals

Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

0 views • 8 slides


Understanding Eligibility for Event-Driven PrEP (ED-PrEP)

Explore eligibility criteria and dosing guidelines for Event-Driven PrEP (ED-PrEP), a preventive medication regimen for individuals at substantial risk for HIV infection. Learn who is eligible, dosing instructions, and how to determine eligibility through specific questions.

0 views • 16 slides


Understanding Drug Testing Policies in the Workplace

The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

0 views • 19 slides