Introduction to Aspen Staged Separation Unit Operations for the purification of desired components by removing impurities and pollutants using distillation, absorption, and stripping columns. This technology is relevant to ammonia synthesis to prevent catalyst poisoning by removing CO2 through absor

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The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

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Pharmacokinetics, as explained in a lecture by Oula Mohammed Sami, M.B.Ch.B/MSc in clinical pharmacology, delves into how the body processes drugs, contrasting with pharmacodynamics which focuses on drug actions. Key topics covered include properties influencing treatment outcomes, the significance

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Exploring the intricate process of water absorption in plants, this course delves into the active and passive methods used by roots to uptake water from soil, the role of osmosis in osmotic active absorption, the influence of transpiration on passive absorption, and the significance of root hairs in

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Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

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Desirable conditions in designing an absorption process include low pressure and high temperature for the gas in and liquid out. Learn about appropriate plots, points on the operating line, absorption factors, minimum absorbent usage, assumptions in McCabe-Thiele analysis, and differences between co

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Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

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This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

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Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

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Absorption costing is a method that includes direct costs and a fair share of production overhead costs in the cost of a product. Overhead absorption rate (OAR) is calculated using budgeted figures and can lead to over/under-absorption. Over-absorption occurs when absorbed overhead is more than actu

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Atomic absorption spectrophotometry (AAS) is a spectro-analytical technique used for quantitative determination of chemical elements through the absorption of light by free atoms. This method is vital in various fields like biophysics, toxicology, and archaeology, allowing the analysis of over 70 di

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Drug absorption is a crucial process in pharmacology, involving the movement of drugs from administration sites to systemic circulation. Explore the definitions, bioavailability, routes of administration, and mechanisms like passive diffusion through cell membranes. Gain insights into how drugs disi

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Absorption of water by plant roots is a crucial process involving osmosis and gradients. The root system structure plays a vital role in water absorption efficiency, with root hairs being key to this process. Factors such as soil penetration depth and root hair characteristics impact the extent of w

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The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

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A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

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Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

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The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

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Therapeutic Drug Monitoring (TDM) utilizes pharmacokinetic principles to optimize drug therapy by balancing efficacy and toxicity levels. Historical background reveals a shift from empirical dosing to precise pharmacokinetic analysis, aiming to minimize toxicity risks and maximize therapeutic benefi

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Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

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In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

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Biopharmaceutics and pharmacokinetics play essential roles in the research, development, and optimization of pharmaceutical products. Biopharmaceutics focuses on the interrelationship of drug properties, dosage forms, and administration routes on drug absorption, while pharmacokinetics delves into d

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Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

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Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

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Partition coefficient (P.C.) is crucial in pharmaceuticals for various reasons such as preserving oil/water systems, drug distribution in the body, extraction processes, and dosage form formulations. It involves the distribution of a solute between two immiscible liquids based on equilibrium express

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Amino acid absorption in the small intestine is an active process requiring energy derived from ATP hydrolysis. It involves two main mechanisms: carrier proteins transport system and glutathione transport system. The carrier proteins transport system uses ATP energy for absorption, while glutathione

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Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

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Understanding pH-solubility profiles of drugs like indomethacin, chlorpromazine, and oxytetracycline is crucial in formulating pharmaceuticals. Factors affecting dissolution rates, such as particle size and solubility, can be optimized to enhance drug absorption. Different methods like particle size

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Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o

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Plants absorb minerals from the soil as ions through the roots, with the process of mineral absorption being distinct from water absorption. Mineral absorption in plants can occur through passive or active methods, each involving different mechanisms and energy requirements. Passive absorption is a

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Research conducted by V. V. Flambaum, J. Jin, and D. Budker at the Gamma Factory (GF) on photoproduction of pionic atoms is detailed in this content. It explores the formation of pionic atoms with negative pions orbiting the nucleus in a hydrogen-like system, emphasizing strong interaction effects a

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The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

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Dissolution is a crucial process for drug absorption, where solid dosage forms must dissolve in gastrointestinal fluid before absorption. Factors affecting dissolution rate include agitation intensity, drug solubility, and surface area exposed to the dissolution medium. Dissolution testing plays a k

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Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

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Gases in the atmosphere absorb radiation through various mechanisms such as changing rotational/vibrational energy and exciting electrons. This absorption plays a crucial role in remote sensing applications. The absorption principles differ for molecules like CO2 and H2O, influencing their vibration

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Plants absorb minerals from the soil in the form of inorganic ions through both passive and active methods. Active mineral absorption requires metabolic energy, whereas passive absorption occurs along the concentration gradient by simple diffusion. The roots play a vital role in mineral absorption d

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This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

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Ocular pharmacology faces challenges in effective drug delivery due to blood-retinal, blood-aqueous, and blood-vitreous barriers that impede high drug concentrations in the eye. Various routes of administration, including topical and local injections, are employed to overcome these barriers. Pharmac

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Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

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The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

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Pharmacokinetics and pharmacology, focused on ADME processes, play a crucial role in drug development and delivery. Absorption, distribution, metabolism, and excretion determine how drugs interact within the body. Absorption involves transfer into the bloodstream, while distribution entails the spre

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