Structural divisions of the central and peripheral nervous systems, learn about neuron anatomy, the neuromuscular junction, and the role of neurotransmitters. Includes information on Acetylcholine, Norepinephrine, Dopamine, and Serotonin.

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Learn about the causes, symptoms, and effects of Vitamin A deficiency, including night blindness, corneal keratinization, and impaired immune function. Explore the epidemiology and pathogenesis of this condition.

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Iron deficiency is prevalent in heart failure patients with reduced ejection fraction and is linked to poor outcomes. The HEART-FID trial investigates the impact of intravenous ferric carboxymaltose (FCM) on all-cause mortality, heart failure hospitalizations, and exercise capacity in chronic HFrEF

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Mental deficiency, also known as intellectual disability, is characterized by significantly below-average intellectual functioning before the age of 18, along with limitations in adaptive behaviors. It is measured using standardized IQ tests, with classifications ranging from profound to mild. Two m

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Antipsychotic drugs, also known as neuroleptics, are essential in treating schizophrenia and other psychotic disorders. They work by targeting dopamine and serotonin receptors in the brain, managing symptoms like hallucinations and delusions. Learn about the dopamine-serotonin hypothesis of schizoph

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Nutritional diseases arise from imbalances between the body's nutrient and energy requirements and their supply. Nutritional deficiencies can lead to clinical diseases, while excessive intake can result in diseases of affluence. Common nutritional disorders include low birth weight, PEM, obesity, go

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Cholestasis is characterized by reduced bile flow and elevated direct bilirubin. It is critical to differentiate it from neonatal jaundice. In conditions like biliary atresia and 1-antitrypsin deficiency, early diagnosis and intervention are crucial to prevent liver failure. Clinical manifestations

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This session covers the differences between cocaine and methamphetamine, focusing on their effects on the brain, particularly the role of dopamine. It explains how dopamine influences pleasure, motivation, and various responses in the body. Imbalance in dopamine levels can lead to a range of symptom

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Vitamin B12 deficiency is a complex condition with various manifestations, including neurological symptoms. The updated guidelines address key areas such as neuro symptoms, coeliac disease, and transitioning from intramuscular to oral treatment. Testing indications and approaches for pernicious anae

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Explore the key differences between cocaine and methamphetamine, how dopamine plays a crucial role in the brain affecting movement, thinking, and pleasure responses. Learn about the effects of dopamine imbalance and the impact of stimulant drugs on dopamine levels over time. Understand the addiction

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Adenosine is used for SVT, Amiodarone for VT/VF, Atropine for bradycardia, Dopamine for shock, and Epinephrine for cardiac arrest. Each medication has specific dosages and side effects. These drugs play crucial roles in advanced cardiac life support scenarios.

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Adrenergic transmission involves the release of neurotransmitters such as norepinephrine, dopamine, and epinephrine at synapses or neuroeffector junctions. These neurotransmitters, known as catecholamines, play crucial roles in transmitting impulses in the sympathetic nervous system and central nerv

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A 78-year-old man presents with symptoms of fatigue, headache, and abdominal pain, leading to a diagnosis of iron deficiency anemia. His medical history includes hypertension, type II diabetes, and chronic shoulder pain. Investigations reveal hypochromic, microcytic anemia with low iron levels and h

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Post-Parturient Haemoglobinuria (PPH) is a metabolic disease affecting high-producing dairy cows after calving, characterized by hemolysis, hemoglobinuria, and anemia. Common in buffaloes and cows, it is caused by phosphorus deficiency in diet, affecting intracellular functions and leading to clinic

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Parkinson's disease is a neurodegenerative disorder that impacts dopamine levels in the brain. The history, epidemiology, causes, and pathophysiology of the disease are explored, shedding light on its significant impact on the nervous system. Genetic and environmental factors play a role in the deve

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Vitamin K deficiency in animals can lead to serious health issues due to its crucial role in blood clotting and bone metabolism. Different sources of vitamin K, such as plant material and bacterial fermentation, provide essential forms like K1 and K2. Factors contributing to deficiency include fat m

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Farmers can benefit from Marketing Assistance Loans (MAL) and Loan Deficiency Payments (LDP) to manage cash flow and ensure price floors for their harvested grain. MAL offers low-interest loans while LDP provides payments if prices fall below a certain level, offering financial support during challe

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Hyperglycemic crises such as Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar State (HHS) are life-threatening emergencies characterized by severe hyperglycemia and metabolic imbalances. DKA involves absolute or near-absolute insulin deficiency leading to ketone body production and systemi

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Elemental analysis of human fingernails is conducted using Laser-Induced Breakdown Spectroscopy (LIBS) to diagnose and monitor zinc deficiency in the body. Zinc deficiency is a significant health issue globally, affecting billions of people. By utilizing LIBS technology on fingernail samples, resear

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This session, led by Dr. Patrick Asamoah Sakyi from the Department of Earth Science at UG, delves into the significance of geological elements in human health, discussing diseases arising from their deficiency or excess intake. Topics include geophagy, fluorine's impact on dental health, iodine defi

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Vitamin E deficiency in poultry can lead to serious conditions such as encephalomalacia (crazy chick disease) and exudative diathesis. Symptoms include ataxia, testicular degeneration, and early embryo mortality. Post-mortem lesions show soft and swollen brains with minute hemorrhages. It is crucial

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Overview of pharmacological treatment options for Parkinson's disease and related conditions like choreatic dyskinesias, spastic disorders, and myasthenia gravis. Describes the degenerative process of Parkinson's disease, its symptoms, and the pharmacological interventions targeting dopamine deficit

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Explore key topics in haematology such as leucopenia, B12 deficiency, and myelodysplastic syndrome with detailed guidance on interpreting full blood counts, red flags, investigations, and management strategies. Learn about special situations like B12 deficiency in pregnancy and malabsorption issues.

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Antipsychotic drugs play a vital role in managing psychotic disorders by targeting dopamine and serotonin receptors. This overview covers the mechanism of action, classification (typical vs. atypical), side effects, and therapeutic efficacy of antipsychotic medications. It also delves into the mood-

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Ongoing work includes progress on CPIC guidelines for aminoglycosides, clopidogrel, and statins, along with evidence reviews for various enzymes and medications. A review of G6PD deficiency and rasburicase safety is being conducted, categorizing drugs as low-to-no risk, high-risk, or medium-risk bas

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Copper deficiency in ruminants can be primary or secondary, affecting enzyme activity and gene expression. Risk factors include diet, soil characteristics, and breed. Pathogenesis involves effects on tissues, wool loss, body weight, diarrhea, anemia, bone health, and heart function.

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In this project, the focus is on identifying splice sites relevant to the inhibitory dopamine receptor gene (D2). The problem involves finding splicing elements within a specific range of known splice sites in the gene. The data provided includes the D2 gene entry in FASTA format, a database of spli

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Explore the key differences between cocaine and methamphetamine, the role of dopamine in the brain, the effects of dopamine imbalance, and the impact of stimulant drugs like shabu/cocaine on dopamine levels over time. Learn about the craving, use, depression, and addiction cycle associated with thes

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Explore the impact of waterlogged soils on nitrogen deficiency in plants and discover the role of active transport, soil oxygen displacement, and chlorophyll production. Engage students in solving the issue through an interactive activity that integrates their knowledge of plant biology concepts.

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G6PD deficiency hemolytic anemia is an inherited condition characterized by reduced levels of glucose-6-phosphate dehydrogenase (G6PD), leading to impaired production of NADPH. This deficiency affects the Pentose Phosphate Pathway (PPP) and can result in oxidative stress, causing damage to DNA, prot

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Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare acquired disorder causing hemolytic anemia due to red cell membrane defects, leading to increased sensitivity to complement. On the other hand, G6PD Deficiency is a genetic condition causing hemolytic anemia due to impaired function of the G6PD enz

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Cocaine affects the brain's reward circuit by blocking dopamine transporters, leading users to associate the drug with a rewarding feeling. Prolonged use can result in internalization of dopamine receptors. By hijacking reward-learning mechanisms, cocaine becomes one of the most harmful and addictiv

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Thiamine (Vitamin B1) deficiency, often seen in conditions like alcoholism and poor dietary intake, can lead to serious health issues such as beriberi. This article delves into the causes, clinical features, and treatment options for thiamine deficiency, including the different types of beriberi and

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Iron deficiency anemia occurs when the body lacks sufficient iron to produce hemoglobin, leading to symptoms like fatigue and weakness. Iron therapy, led by professionals like Dr. Haider Raheem, helps restore iron levels. Important information includes body iron distribution, absorption mechanisms,

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Understanding the clinical presentation and risks of Vitamin D deficiency in infants, especially those who are breastfed, is crucial. This curriculum covers acute versus chronic presentations of deficiency, associated symptoms, and risk factors such as sunlight exposure, geographical location, air q

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Dr. Methal A. Alrubaie, an assistant professor, presents a detailed overview of anemia in pregnancy. The content covers the classification of anemia types, their etiology, clinical presentation, effects on both mother and fetus, investigation methods, and treatment approaches. Various types of anemi

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Limbal stem cell deficiency (LSCD) is a rare condition characterized by inadequate corneal rejuvenation and conjunctivalization of the cornea. In this case study, a 14-year-old male with Vernal Keratoconjunctivitis presented with itching, eye rubbing, and corneal epithelial scarring resembling a who

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Individuals with intellectual deficiency or mental retardation may exhibit immature behaviors, lack judgment, and show signs of delayed development. They require special care, early diagnosis, parental assistance, and educational support to reach a reasonable degree of educational achievement and so

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Carlsson et al.'s 2000 study on schizophrenia explores the dopamine hypothesis, highlighting the interplay of neurotransmitters like glutamate, serotonin, and GABA. They suggest future drug treatments for schizophrenia, emphasizing the need to consider neurotransmitter interactions beyond dopamine.

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Primary immunodeficiencies are a group of disorders characterized by defects in the immune system. Severe Combined Immunodeficiency (SCID) and related conditions like JAK-3 deficiency, IL-7 R or CD45 deficiency, and Omenn syndrome are discussed in detail, highlighting the genetic basis, clinical man

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