This prospective, multicentre, randomised clinical trial led by Dr. Tiffany Patterson aims to determine whether direct delivery to a cardiac arrest centre following non-ST elevation out-of-hospital cardiac arrest reduces deaths compared to delivery to the nearest emergency department. Funded by the

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This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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This unit delves into the application of social psychology in the legal system, exploring the nature of criminal behavior, responses to criminal acts, the criminal justice system, and rehabilitation. It examines the social ecological perspective of criminal acts and outlines key points related to th

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Empagliflozin's impact on cardiovascular and renal events in heart failure with reduced ejection fraction was assessed in the EMPEROR-Reduced trial led by Milton Packer, MD, and Faiez Zannad, MD. The trial, enriched for patients with severe left ventricular dysfunction, randomized participants to em

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Explore the process of simulating clinical trial designs, including traditional and adaptive approaches. Learn how to generate data, conduct analysis, make within-trial decisions, and summarize results using fixed-sample two-arm parallel group trials and group-sequential designs. Dive into methods l

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The UK Mini Mitral Trial compares the outcomes of minimally invasive thoracoscopic-guided right minithoracotomy versus conventional sternotomy for mitral valve repair. The trial aims to determine if physical function improvement post-surgery at 12 weeks is superior in the minimally invasive approach

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Explore the various types of hearings available in the Court Management System, such as Motion Calendar, Special Sets, Calendar Call/Trial, Pre-Trial Conference, and Case Management. Learn how to set up new hearings/events and understand the process of generating trial orders and pre-trial conferenc

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The STRESS-L Trial focuses on reversing septic shock using Landiolol, a beta-blockade treatment. It provides training for non-GCP trained clinicians involved in eligibility review, medical care, and prescribing in the trial. The slides cover key GCP principles, trial agenda, study information, backg

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The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the trial focuses on clinical and c

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ACST-2 is a randomized trial comparing carotid artery stenting (CAS) versus carotid artery surgery (CEA) in asymptomatic patients with severe carotid stenosis. The trial, published in The Lancet in August 2021, involved 3625 patients. While surgery has been shown to reduce stroke rates, modern medic

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The Sixth Amendment guarantees various rights during criminal trials, such as a speedy and public trial, trial by jury, notice of accusations, the right to confront witnesses, and the assistance of counsel. Defendants can opt for a bench trial where the judge decides innocence or guilt. Juries, typi

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The CLEAR Trial is a 2x2 factorial randomized trial examining the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley from Queen's University Belfast, the study focuses on exacerbation ma

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NCI-MATCH is a groundbreaking clinical trial aiming to match tumor gene alterations with targeted therapies. The interim analysis results revealed impressive patient enrollment and site participation exceeding expectations. Despite challenges with pausing new patient registrations for the analysis,

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Understanding the key components of a clinical trial research protocol is essential for conducting successful studies. This includes identifying session objectives, discussing trial protocol contents, exploring observational study elements, and learning about reporting guidelines. Study objectives f

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Enhance your trial skills in family law with a focus on evidence collection, trial strategies, and client examination. Learn best practices for preserving evidence, drafting persuasive statements, and navigating trials confidently. This workshop covers important aspects of evidence collection, such

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Explore the innovative tool nQuery Predict for accurate clinical trial milestone predictions, demonstrated in a webinar hosted by industry experts. Learn about key milestones, adaptive design considerations, enrollment predictions, and the significance of statistical approaches in optimizing trial d

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Asset recovery in England and Wales involves a combination of criminal and civil proceedings to secure justice and return funds to victims of crime. The CPS's Proceeds of Crime Division plays a crucial role in obtaining Restraint Orders and Confiscation Orders. Civil recovery, focusing on illicit fi

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Exploring the detailed process of civil rights litigation, covering steps from fact gathering to trial preparation and post-trial activities. The visual presentation showcases key elements such as client retention, complaint filing, discovery phases, trial preparation, and post-trial procedures like

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Explore the differences between civil and criminal law, covering civil trial steps, Miranda Rights, pleadings, and more. Discover the nuances of civil trials, starting with a complaint, and criminal trials, which begin with an arrest. Learn about the Miranda Rights and the essential stages of a civi

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Simulation competition where students portray attorneys and witnesses in a civil jury trial based on the case of professional writer Riley Winter suing an online magazine for wrongful termination due to age discrimination. Judges preside over the trial, score performances, and provide feedback, focu

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This content explores various aspects of the criminal justice system, including the adversarial system, classification of offenses, criminal court systems, trial procedures, plea bargaining, and more. It covers models of criminal justice systems, classification of offenses, modes of trial, sending f

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Exploring the complexities of the criminal justice system, this content delves into the adversarial system, classification of offenses, criminal court system, modes of trial, plea bargaining, trial procedures, and various criminal process models.

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Czech criminal procedure combines inquisitorial and accusatorial models, with the pre-trial phase led by the public prosecutor and the trial phase overseen by a judge. Inspired by the Anglo-American adversarial system, Czech proceedings feature deviations tailored to the continental model. Key princ

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In this competition, students simulate a criminal jury trial where they take on roles as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves State v. Sinclair, focusing on the murder trial of Skyler Sinclair, a suspect in the death of an undercover officer

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction with its own laws. This year's case involves the attempted murder of a spouse. Judges preside, score, provide feedback, and reach a verdict in panels. The trial follows a structured outline

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In criminal trials, the handling of classified information is crucial and governed by specific rules. Defendants do not have an inherent right to access classified information, and there are procedures in place to determine its use in court. The rights surrounding secret evidence include protection

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The Code of Criminal Procedure 1973 Chapter 19 outlines the procedure for trial of warrant cases by magistrates where the prosecution presents evidence to support the case against the accused. Section 244 requires the magistrate to hear the prosecution and take all evidence presented. If the evidenc

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AIRWAYS-3 is a multi-centre, open-label, randomized trial evaluating the clinical and cost effectiveness of a supraglottic airway (SGA) versus tracheal intubation during in-hospital cardiac arrest (IHCA). The trial aims to determine the functional status and health-related quality of life outcomes o

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The CLEAR Trial is a 2x2 factorial randomized trial led by Professor Stuart Elborn and Professor Judy Bradley to assess the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves various study sites and potential new sit

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Understanding the role and benefits of partnering with a Clinical Trial Unit (CTU) is essential for potential Chief Investigators. A CTU handles various aspects of trial coordination, from developing trial materials to overseeing regulatory permissions and data management. UK Clinical Trials Units (

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The trial of O.J. Simpson for the brutal murders of Nicole Brown Simpson and Ron Goldman captivated the nation, with overwhelming evidence implicating Simpson. Despite the compelling case against him, Simpson's defense team, led by Johnnie Cochran, raised doubts about the integrity of the evidence a

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Participants are preparing for the trial of King Louis XVI by researching charges, roles, and responsibilities. The trial process includes reading indictments, opening statements, questioning phases, and final statements. Each role, including Louis, Marie, Robespierre, Marat, and a woman from the 3r

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Understanding who commits crime and why certain individuals are more likely to engage in criminal activities involves exploring a range of social and biological factors. While biology suggests a genetic predisposition to criminal behavior, sociology emphasizes the influence of social factors like fa

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Simulation of a criminal jury trial where students act as attorneys and witnesses in a fictitious jurisdiction called Midlands. This year's case involves the attempted murder of Kerry Bell-Leon, with witness selection varying in each round. Judges play crucial roles in presiding over the trial, scor

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The relationship between criminal investigations and civil tax audits in Sweden is explored, highlighting how tax audits and criminal proceedings run concurrently. The mens rea requirement for criminal sanctions and tax surcharge, as well as the integration between criminal sanctions and tax surchar

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The CLEAR Trial, led by Professor Stuart Elborn and Professor Judy Bradley, aims to assess the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. The trial involves a 2x2 factorial design and various study sites acros

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The CLEAR Trial is a 2x2 factorial randomized trial assessing the clinical and cost-effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients over 52 weeks. Led by Professor Stuart Elborn and Professor Judy Bradley, the trial involves randomization, sealed

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Explore the key aspects of criminal law and procedure, including definitions of crime, the role of criminal procedure, sources of law, phases of the criminal process, participants involved, and rules of evidence in legal proceedings. Gain insight into how criminal law is distinct from civil law and

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Explore the key elements of a criminal trial process, including plea bargains, right to jury trial, speedy trial, confronting witnesses, and freedom from self-incrimination. Learn about the defendant's options in case of wrongful conviction and the sentencing procedures undertaken by judges.

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Speedy trial rights in juvenile cases are crucial for ensuring timely resolution of legal proceedings. According to Florida laws, the speedy trial time period is 90 days from the date the child was taken into custody or served with a summons. Failure to commence the adjudicatory hearing within this

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