Checkpoint inhibitors - PowerPoint PPT Presentation


Statistical representations, measures and analysis

Explore a comprehensive collection of checkpoint activities in mathematics for Year 8 students focusing on statistical representations, measures, and analysis. Engage with seventeen checkpoint activities and twelve additional activities published in 2022/23. Delve into topics such as comparing chart

0 views • 47 slides


Diagnostic Mathematics Activities for Understanding Multiplicative Relationships

Explore a series of checkpoint activities focused on fractions, ratios, and multiplicative relationships in mathematics. The checkpoints cover various topics such as pay rises, multiplication squares, true or false statements, and examples of multiplicative relationships. Engage in thought-provoking

2 views • 51 slides



SGLT-2 inhibitors and AKI

Consultant Nephrologist Paraskevi Liaveri discusses the association between SGLT-2 inhibitors and acute kidney injury (AKI). Pharmacovigilance reports highlight a higher risk of AKI with these drugs, especially when combined with RAAS blockers, diuretics, or NSAIDs. Studies suggest potential mechani

0 views • 49 slides


Mathematical Checkpoints and Equations Activities for Year 7 Students

Engage Year 7 students in a series of 16 checkpoint activities and 12 additional activities focused on expressions, equations, and mathematical concepts. Explore topics like checks and balances, shape balance, equations from bar models, number line concepts, and more to enhance mathematical understa

3 views • 42 slides


Graphical representations of linear relationships

This material includes a series of checkpoint activities and additional tasks related to graphical representations of linear relationships for Year 8 students. Students will engage in tasks such as plotting points on coordinate grids, analyzing ant movements, exploring different rules for plotting p

1 views • 51 slides


Exploring Perimeter and Area in Mathematics Checkpoints for Year 7

Dive into a series of engaging activities focused on perimeter and area concepts in mathematics for Year 7 students. Discover various checkpoint tasks, additional activities, and animated solutions to enhance understanding and application of geometric principles. Explore topics such as shapes on a g

1 views • 43 slides


Cambridge Checkpoint Examination Information and Guidelines

Cambridge Checkpoint examinations are conducted by the University of Cambridge, UK for students in Year 6 to Year 9. The exams cover subjects like English, Mathematics, and Science, with specific paper formats and grading criteria. Exam dates typically fall between 10th to 28th April, and fees must

1 views • 8 slides


Understanding COX Enzymes and Their Impact on Pain and Inflammation

COX enzymes, including COX1, COX2, and COX3, play a crucial role in synthesizing prostanoids like prostaglandins in the body, affecting pain and inflammation. By inhibiting these enzymes, relief from pain and inflammation can be achieved. However, non-selective COX inhibitors may lead to various sid

0 views • 21 slides


Year 8 Mathematics Checkpoint Activities: Sequences & More

Dive into the diagnostic mathematics activities aimed at Year 8 students, focusing on sequences. The publication includes twenty-two Checkpoint activities with additional exercises, covering topics like adders, counting counters, same jump comparisons, and multiples. Explore the underpinnings of mat

0 views • 51 slides


Factors Affecting Enzyme Activity and Catalysis

Enzyme activity is influenced by various factors such as enzyme concentration, temperature, pH, substrate concentration, inhibitors, activators, and physical agents. The rate of enzyme-catalyzed reactions is directly proportional to enzyme concentration, and temperature plays a significant role with

0 views • 23 slides


Year 8 Diagnostic Mathematics Checkpoints: Perimeter, Area, and Volume Activities

Dive into a comprehensive collection of 28 Checkpoint activities, alongside 11 additional exercises, designed for Year 8 students to strengthen their understanding of perimeter, area, and volume. This newly published resource is packed with engaging tasks such as working with bricks, analyzing line

0 views • 68 slides


ConCORD: Exploiting Memory Content Redundancy Through Content-aware Services

Memory content-sharing detection and tracking are crucial aspects that should be built as separate services. ConCORD, a distributed system, efficiently tracks memory content across entities like VMs and processes, reducing memory footprint size and enhancing performance. The implementation involves

0 views • 56 slides


Year 8 Diagnostic Mathematics Constructions Activities - Checkpoints 1-8

Engage with a series of 22 Checkpoint activities and 16 additional activities focusing on constructions in mathematics for Year 8 students. Published in 2022/23, the topics range from basic Circle constructions to more complex arrangements involving multiple circles. Each Checkpoint explores a diffe

0 views • 64 slides


Corrosion Prevention Methods in Chemical Engineering

Define oxidation, reduction, oxidizing agent, reducing agent, standard electrode potential, Nernst equation, and corrosion in the context of chemical engineering. Discuss different forms of corrosion, including uniform corrosion, galvanic corrosion, pitting corrosion, and stress corrosion. Explore m

0 views • 20 slides


Overview of Antihypertensive Agents and their Mechanisms of Action

Explore the classification of antihypertensive agents used in treating hypertension, including beta blockers, centrally acting agents, ganglionic blockers, ACE inhibitors, vasodilators, and more. Learn about the Renin-Angiotensin System, ACE inhibitors, and specific drugs like Captopril and Benazepr

0 views • 9 slides


Linear Equations Checkpoint Activities for Year 8 Students

This diagnostic mathematics resource for Year 8 students focuses on solving linear equations through a series of Checkpoint and additional activities. Published in 2021/22, the content covers topics such as representing equations with algebra and solving for unknown variables. Students will engage w

0 views • 47 slides


Ship Repair and Alteration Committee Updates and Key Changes - SSRAC 2019

The SSRAC 2019 meeting discussed standard specifications for ship repair and alteration, subcommittee details, hull preservation processes, NSI NAVSEA standard items, and key changes in quality management, deck covering, cleaning, and painting requirements. Notable modifications include reduced chec

5 views • 14 slides


Custody Training Checkpoint at Surrey Police

This training program at Surrey Police focuses on the importance of data quality, specifically emphasizing accuracy, relevance, and timeliness of data entry. It covers the process of Checkpoint within Custody, eligibility criteria, and the introduction of Checkpoint Plus. Surrey Checkpoint aims to r

0 views • 24 slides


Mathematics Transformation Checkpoint Activities for Year 7 Students

Engage Year 7 students with 24 Checkpoint and 11 additional activities focused on transformations, including tessellations and pentominoes. Explore concepts such as triangles and codes to enhance mathematical understanding. Ideal for a diagnostic assessment to identify areas of strengths and areas n

0 views • 76 slides


Understanding Enzyme Inhibition in Biochemistry

Enzyme inhibition plays a crucial role in pharmacology and biochemistry by regulating enzymatic reactions. Inhibitors can be reversible or irreversible, affecting enzyme activity differently. Competitive, uncompetitive, and noncompetitive inhibition types are explained along with examples like diiso

0 views • 20 slides


Cambridge Checkpoint Exams: Information and Guidelines for Parents and Students

Detailed information about the Cambridge Checkpoint exams including exam structure, subjects, grading system, exam dates, fees, and resources for revision. Parents and students can find useful insights and guidelines to prepare for the exams effectively.

0 views • 8 slides


Regulation of the Cell Cycle: A Comprehensive Overview

Variation in cell cycle length in humans, controlled by internal and external mechanisms, with special proteins and checkpoint systems ensuring proper progression. External events trigger initiation and inhibition of cell division, while internal checkpoints maintain genetic integrity and chromosome

4 views • 14 slides


Effective Checkpoint Set-Up and Operation Guidelines

Learn about setting up and operating checkpoints to ensure the health and safety of animals and prevent the spread of diseases. The content covers identifying vehicles with infected or susceptible animals, location selection, necessary equipment and supplies, personnel requirements, basic operation

0 views • 20 slides


Understanding Enzyme Inhibition in Acid Phosphatase Kinetics

In this experiment, the effect of inhibitors on enzymatic reactions, specifically acid phosphatase, is explored. Different types of inhibition (competitive, noncompetitive, uncompetitive) are examined, along with reversible and irreversible inhibitors. The study aims to determine the type of inhibit

1 views • 17 slides


Antibiotic Prescribing Impact on Clostridium Difficile Risk in Patients on Protein Pump Inhibitors

Antibiotic prescribing in patients on protein pump inhibitors (PPIs) is associated with an increased risk of Clostridium difficile infection. A review was conducted on high-risk antibiotic prescriptions, revealing instances where patients were prescribed against guidelines, leading to potential comp

0 views • 5 slides


Understanding Antipsychotics and Antidepressants in Veterinary Pharmacology

Antipsychotics and antidepressants play crucial roles in treating psychological and affective disorders in veterinary medicine. Antidepressants are vital in managing abnormal mood and behavior linked to depression, while antipsychotics help address various nervous disorders. The classification of an

0 views • 11 slides


Optimizing Foundational Treatments for HFrEF: Guideline Recommendations and Implementation Strategies

Highlighting the current guideline recommendations for treating patients with Heart Failure with Reduced Ejection Fraction (HFrEF), this educational slide module emphasizes the importance of implementing the recommended therapies effectively. It covers the foundational treatments recommended by vari

0 views • 28 slides


Understanding Dormancy in Plants: Causes and Implications

Dormancy in plants, involving seeds and buds, is a state where growth is temporarily halted due to internal or external factors. Factors like immature embryos, impermeable seed coats, and growth inhibitors contribute to seed dormancy. The presence of inhibitors like abscisic acid and the influence o

0 views • 43 slides


Evolution of Immunotherapy in Cancer Treatment

The history and advancements in cancer immunotherapy are highlighted, from early observations in the 1890s to the development of modern immunotherapies in the 2000s. Concepts such as immunosurveillance theory and the role of T cells in recognizing tumor-associated antigens are discussed, leading to

0 views • 22 slides


Inspiring Educational Berlin Tour for Schools - Equity Adventures

Join Equity for an educational trip to Berlin that offers inspiring learning experiences for young students in years 7 and 8. Explore key historical sites like the Wannsee mansion, Topography of Terror, and Checkpoint Charlie while delving into the rich cultural heritage of the city. With over 80 ye

0 views • 7 slides


Immune Cell Analysis Supplementary Figures

This collection of supplementary figures provides detailed flow cytometry data on immune cell populations, including CD4+ T cells, CD8+ T cells, tumor-associated macrophages, and more. The figures also include information on immune checkpoint molecules like PD-L1 and TIGIT. Each figure presents spec

0 views • 4 slides


Exploring the Diverse Applications of PDE-5 Inhibitors Beyond Erectile Dysfunction

Discover how PDE-5 inhibitors go beyond treating erectile dysfunction, with approved and emerging compounds, alternative dose regimens, concentration sites, and potential targets like cardiovascular diseases and the central nervous system.

0 views • 47 slides


mTOR Inhibitors in Liver Transplantation for HCC: Recent Updates and Clinical Trials

Exploring the use of mTOR inhibitors in liver transplantation for hepatocellular carcinoma (HCC), this content presents recent study results and experiences from the Korean population. It discusses the preventive potential of mTOR inhibitors in HCC recurrence based on previous studies and the need f

0 views • 32 slides


Guideline Recommendations for SGLT2 Inhibitors in Heart Failure

This educational slide module provides an overview of the guideline recommendations for SGLT2 inhibitors in the treatment of heart failure, including HFrEF, HFmrEF, and HFpEF. It covers recommendations from AHA, ACC, HFSA, ESC, CCS, and CHFS guidelines, highlighting the role of SGLT2 inhibitors as a

0 views • 28 slides


Understanding Antifungal Inhibitors and Drugs

In this detailed overview, we explore antifungal inhibitors and drugs, including their mechanisms of action, impact on eukaryotes and prokaryotes, common agents affecting fungal sterols and cell walls, as well as synthetic antifungals. From polyenes like nystatin to azoles such as voriconazole, this

0 views • 12 slides


Understanding Enzyme Regulation and Factors Affecting Enzyme Activity

Organisms carefully control enzyme production and activation as per varying needs and conditions within cells. Enzyme activity is influenced by factors such as pH, temperature, regulatory molecules, cofactors, compartmentalization, covalent modification, and feedback inhibition. Enzymes can be regul

0 views • 20 slides


Comparison of Protease Inhibitors in ARTEMIS Study

This study compares the efficacy and safety of different protease inhibitors (PIs) including ATV, ATV/r, LPV/r, FPV/r, DRV/r, and SQV/r in HIV treatment. The ARTEMIS study specifically focuses on comparing DRV/r and LPV/r in combination with TDF/FTC in ARV-naive patients. Results show non-inferiorit

0 views • 12 slides


Comprehensive Overview of Immunotherapy in Bladder and Renal Cancer Management

Explore the latest advancements in immunotherapy for managing bladder and renal cancer, including mechanisms of action, indications, adverse effects, and available treatment regimes. Learn about immune checkpoint inhibitors, differentiating immunotherapy from chemotherapy, indications for use across

0 views • 19 slides


Therapies and Strategies for ER-Positive, HER2-Negative Metastatic Breast Cancer

Explore the selection and sequence of therapy for ER-positive, HER2-negative metastatic breast cancer, along with novel agents and strategies under evaluation. Learn about cases of postmenopausal women with metastatic breast cancer, CDK4/6 inhibitors, and the impact of targeted therapies on patient

0 views • 23 slides


Understanding PCSK9 Inhibitors for Cardiovascular Health

PCSK9 inhibitors are a novel class of medications that help lower LDL cholesterol levels, reducing the risk of cardiovascular events. This article covers their mechanism of action, patient groups benefiting from them, efficacy in LDL-C lowering, and safety considerations. Learn how PCSK9 inhibitors

0 views • 8 slides