Checkpoint inhibitors - PowerPoint PPT Presentation


Statistical representations, measures and analysis

Explore a comprehensive collection of checkpoint activities in mathematics for Year 8 students focusing on statistical representations, measures, and analysis. Engage with seventeen checkpoint activities and twelve additional activities published in 2022/23. Delve into topics such as comparing chart

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Diagnostic Mathematics Activities for Understanding Multiplicative Relationships

Explore a series of checkpoint activities focused on fractions, ratios, and multiplicative relationships in mathematics. The checkpoints cover various topics such as pay rises, multiplication squares, true or false statements, and examples of multiplicative relationships. Engage in thought-provoking

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SGLT-2 inhibitors and AKI

Consultant Nephrologist Paraskevi Liaveri discusses the association between SGLT-2 inhibitors and acute kidney injury (AKI). Pharmacovigilance reports highlight a higher risk of AKI with these drugs, especially when combined with RAAS blockers, diuretics, or NSAIDs. Studies suggest potential mechani

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Mathematical Checkpoints and Equations Activities for Year 7 Students

Engage Year 7 students in a series of 16 checkpoint activities and 12 additional activities focused on expressions, equations, and mathematical concepts. Explore topics like checks and balances, shape balance, equations from bar models, number line concepts, and more to enhance mathematical understa

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Understanding Peptic Ulcer Disease: Causes, Symptoms, and Treatment

Peptic ulcer disease (PUD) involves ulcerations in the duodenal or gastric mucosa caused by factors like Helicobacter pylori infection and NSAID use. Symptoms include abdominal pain and nausea, and treatment often involves H. pylori eradication and proton pump inhibitors to prevent complications lik

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Graphical representations of linear relationships

This material includes a series of checkpoint activities and additional tasks related to graphical representations of linear relationships for Year 8 students. Students will engage in tasks such as plotting points on coordinate grids, analyzing ant movements, exploring different rules for plotting p

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Exploring Perimeter and Area in Mathematics Checkpoints for Year 7

Dive into a series of engaging activities focused on perimeter and area concepts in mathematics for Year 7 students. Discover various checkpoint tasks, additional activities, and animated solutions to enhance understanding and application of geometric principles. Explore topics such as shapes on a g

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DEVELOPMENT OF INTERATRIAL AND INTERVENTRICULAR SEPTUM

Human heart development begins in the 3rd week of gestation with the formation of heart tubes that eventually differentiate into various cardiac structures. The heart undergoes folding and septation processes during development, leading to the formation of crucial septa. Molecular regulation, involv

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Cambridge Checkpoint Examination Information and Guidelines

Cambridge Checkpoint examinations are conducted by the University of Cambridge, UK for students in Year 6 to Year 9. The exams cover subjects like English, Mathematics, and Science, with specific paper formats and grading criteria. Exam dates typically fall between 10th to 28th April, and fees must

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HYPOLIPIDEMIC DRUGS

Major lipids like cholesterol and triglycerides play essential roles in the body, but their excess can lead to hyperlipidemia and related conditions. This overview covers the biosynthesis of cholesterol, triglycerides, and the transport of lipids in the bloodstream, discussing the importance of lipo

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Regulation of Energy Homeostasis by AMPK System and Its Modulation Factors

The AMPK system plays a crucial role in regulating energy homeostasis by sensing the cellular AMP:ATP ratio and responding to metabolic stresses that affect ATP production or consumption. AMPK is activated by factors such as hypoxia, glucose deprivation, and metabolic inhibitors, as well as by compo

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Understanding COX Enzymes and Their Impact on Pain and Inflammation

COX enzymes, including COX1, COX2, and COX3, play a crucial role in synthesizing prostanoids like prostaglandins in the body, affecting pain and inflammation. By inhibiting these enzymes, relief from pain and inflammation can be achieved. However, non-selective COX inhibitors may lead to various sid

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Year 8 Mathematics Checkpoint Activities: Sequences & More

Dive into the diagnostic mathematics activities aimed at Year 8 students, focusing on sequences. The publication includes twenty-two Checkpoint activities with additional exercises, covering topics like adders, counting counters, same jump comparisons, and multiples. Explore the underpinnings of mat

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Factors Affecting Enzyme Activity and Catalysis

Enzyme activity is influenced by various factors such as enzyme concentration, temperature, pH, substrate concentration, inhibitors, activators, and physical agents. The rate of enzyme-catalyzed reactions is directly proportional to enzyme concentration, and temperature plays a significant role with

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Year 8 Diagnostic Mathematics Checkpoints: Perimeter, Area, and Volume Activities

Dive into a comprehensive collection of 28 Checkpoint activities, alongside 11 additional exercises, designed for Year 8 students to strengthen their understanding of perimeter, area, and volume. This newly published resource is packed with engaging tasks such as working with bricks, analyzing line

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ConCORD: Exploiting Memory Content Redundancy Through Content-aware Services

Memory content-sharing detection and tracking are crucial aspects that should be built as separate services. ConCORD, a distributed system, efficiently tracks memory content across entities like VMs and processes, reducing memory footprint size and enhancing performance. The implementation involves

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Year 8 Diagnostic Mathematics Constructions Activities - Checkpoints 1-8

Engage with a series of 22 Checkpoint activities and 16 additional activities focusing on constructions in mathematics for Year 8 students. Published in 2022/23, the topics range from basic Circle constructions to more complex arrangements involving multiple circles. Each Checkpoint explores a diffe

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Corrosion Prevention Methods in Chemical Engineering

Define oxidation, reduction, oxidizing agent, reducing agent, standard electrode potential, Nernst equation, and corrosion in the context of chemical engineering. Discuss different forms of corrosion, including uniform corrosion, galvanic corrosion, pitting corrosion, and stress corrosion. Explore m

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Overview of Antihypertensive Agents and their Mechanisms of Action

Explore the classification of antihypertensive agents used in treating hypertension, including beta blockers, centrally acting agents, ganglionic blockers, ACE inhibitors, vasodilators, and more. Learn about the Renin-Angiotensin System, ACE inhibitors, and specific drugs like Captopril and Benazepr

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Linear Equations Checkpoint Activities for Year 8 Students

This diagnostic mathematics resource for Year 8 students focuses on solving linear equations through a series of Checkpoint and additional activities. Published in 2021/22, the content covers topics such as representing equations with algebra and solving for unknown variables. Students will engage w

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Ship Repair and Alteration Committee Updates and Key Changes - SSRAC 2019

The SSRAC 2019 meeting discussed standard specifications for ship repair and alteration, subcommittee details, hull preservation processes, NSI NAVSEA standard items, and key changes in quality management, deck covering, cleaning, and painting requirements. Notable modifications include reduced chec

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Custody Training Checkpoint at Surrey Police

This training program at Surrey Police focuses on the importance of data quality, specifically emphasizing accuracy, relevance, and timeliness of data entry. It covers the process of Checkpoint within Custody, eligibility criteria, and the introduction of Checkpoint Plus. Surrey Checkpoint aims to r

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Mathematics Transformation Checkpoint Activities for Year 7 Students

Engage Year 7 students with 24 Checkpoint and 11 additional activities focused on transformations, including tessellations and pentominoes. Explore concepts such as triangles and codes to enhance mathematical understanding. Ideal for a diagnostic assessment to identify areas of strengths and areas n

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Understanding Enzyme Inhibition in Biochemistry

Enzyme inhibition plays a crucial role in pharmacology and biochemistry by regulating enzymatic reactions. Inhibitors can be reversible or irreversible, affecting enzyme activity differently. Competitive, uncompetitive, and noncompetitive inhibition types are explained along with examples like diiso

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Cambridge Checkpoint Exams: Information and Guidelines for Parents and Students

Detailed information about the Cambridge Checkpoint exams including exam structure, subjects, grading system, exam dates, fees, and resources for revision. Parents and students can find useful insights and guidelines to prepare for the exams effectively.

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Regulation of the Cell Cycle: A Comprehensive Overview

Variation in cell cycle length in humans, controlled by internal and external mechanisms, with special proteins and checkpoint systems ensuring proper progression. External events trigger initiation and inhibition of cell division, while internal checkpoints maintain genetic integrity and chromosome

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Effective Checkpoint Set-Up and Operation Guidelines

Learn about setting up and operating checkpoints to ensure the health and safety of animals and prevent the spread of diseases. The content covers identifying vehicles with infected or susceptible animals, location selection, necessary equipment and supplies, personnel requirements, basic operation

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Understanding Enzyme Inhibition in Acid Phosphatase Kinetics

In this experiment, the effect of inhibitors on enzymatic reactions, specifically acid phosphatase, is explored. Different types of inhibition (competitive, noncompetitive, uncompetitive) are examined, along with reversible and irreversible inhibitors. The study aims to determine the type of inhibit

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Antibiotic Prescribing Impact on Clostridium Difficile Risk in Patients on Protein Pump Inhibitors

Antibiotic prescribing in patients on protein pump inhibitors (PPIs) is associated with an increased risk of Clostridium difficile infection. A review was conducted on high-risk antibiotic prescriptions, revealing instances where patients were prescribed against guidelines, leading to potential comp

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Understanding Antipsychotics and Antidepressants in Veterinary Pharmacology

Antipsychotics and antidepressants play crucial roles in treating psychological and affective disorders in veterinary medicine. Antidepressants are vital in managing abnormal mood and behavior linked to depression, while antipsychotics help address various nervous disorders. The classification of an

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Optimizing Foundational Treatments for HFrEF: Guideline Recommendations and Implementation Strategies

Highlighting the current guideline recommendations for treating patients with Heart Failure with Reduced Ejection Fraction (HFrEF), this educational slide module emphasizes the importance of implementing the recommended therapies effectively. It covers the foundational treatments recommended by vari

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Understanding Dormancy in Plants: Causes and Implications

Dormancy in plants, involving seeds and buds, is a state where growth is temporarily halted due to internal or external factors. Factors like immature embryos, impermeable seed coats, and growth inhibitors contribute to seed dormancy. The presence of inhibitors like abscisic acid and the influence o

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Evolution of Immunotherapy in Cancer Treatment

The history and advancements in cancer immunotherapy are highlighted, from early observations in the 1890s to the development of modern immunotherapies in the 2000s. Concepts such as immunosurveillance theory and the role of T cells in recognizing tumor-associated antigens are discussed, leading to

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Inspiring Educational Berlin Tour for Schools - Equity Adventures

Join Equity for an educational trip to Berlin that offers inspiring learning experiences for young students in years 7 and 8. Explore key historical sites like the Wannsee mansion, Topography of Terror, and Checkpoint Charlie while delving into the rich cultural heritage of the city. With over 80 ye

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Immune Cell Analysis Supplementary Figures

This collection of supplementary figures provides detailed flow cytometry data on immune cell populations, including CD4+ T cells, CD8+ T cells, tumor-associated macrophages, and more. The figures also include information on immune checkpoint molecules like PD-L1 and TIGIT. Each figure presents spec

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Exploring the Diverse Applications of PDE-5 Inhibitors Beyond Erectile Dysfunction

Discover how PDE-5 inhibitors go beyond treating erectile dysfunction, with approved and emerging compounds, alternative dose regimens, concentration sites, and potential targets like cardiovascular diseases and the central nervous system.

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mTOR Inhibitors in Liver Transplantation for HCC: Recent Updates and Clinical Trials

Exploring the use of mTOR inhibitors in liver transplantation for hepatocellular carcinoma (HCC), this content presents recent study results and experiences from the Korean population. It discusses the preventive potential of mTOR inhibitors in HCC recurrence based on previous studies and the need f

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Guideline Recommendations for SGLT2 Inhibitors in Heart Failure

This educational slide module provides an overview of the guideline recommendations for SGLT2 inhibitors in the treatment of heart failure, including HFrEF, HFmrEF, and HFpEF. It covers recommendations from AHA, ACC, HFSA, ESC, CCS, and CHFS guidelines, highlighting the role of SGLT2 inhibitors as a

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Innovative Approaches in Salvage Chemotherapy for Hodgkin Lymphoma

Salvage chemotherapy plays a significant role in treating relapsed or refractory Hodgkin lymphoma patients before undergoing high-dose chemotherapy and autologous stem cell transplantation. Recent studies highlight the promising results of various salvage regimens, including functional imaging-based

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Developmental Milestones for Young Children: EYFS 2021 Overview

Explore the key developmental milestones for young children at various checkpoints according to the EYFS 2021 Curriculum. From developing friendships and communication skills to cognitive and physical abilities, this guide provides a detailed overview of what children should roughly demonstrate at e

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