Pathology Acute kidney injury
Guidelines of renal biopsy, types of acute kidney injury, clinical manifestations, and pathological findings in this comprehensive lecture. Explore the normal anatomy and histology of the kidney, terminology, etiology, pathophysiology, and more.
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Central America Hemoptysis Case Analysis
A 40-year-old male from Central America presented with 2-month hemoptysis history, dyspnea, chest pain, weight loss, and night sweats. Initial tests showed nodular opacities and cavitary lesions. Biopsy revealed Paracoccidioides infection treated with itraconazole. Clinical improvement noted.
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Europe Cancer Diagnostics Market: Emerging Trends in Liquid Biopsy and Next-Gene
The Europe Cancer Diagnostics Market is projected to reach $12.21 billion by 2031, at a CAGR of 5.6% during the forecast period 2024\u20132031. The Europe cancer diagnostics market is driven by the rising prevalence of cancer, supporting initiatives for early cancer diagnosis, increasing investments
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Understanding Malignant Melanoma: Types, Signs, and Prognosis
Malignant melanoma is a serious skin cancer with various types, including superficial spreading, nodular, acral lentiginous, lentigo maligna, and amelanotic. Recognizing early signs such as ABCDEF (Asymmetry, Borders, Colour, Diameter, Evolving, Funny-looking) is crucial for prompt diagnosis. Macros
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Cost-Benefit Analyses for Liquid Biopsy Studies: Understanding Health Economics and Decision Making
Health economics and decision making play a crucial role in evaluating the clinical utility and cost-effectiveness of liquid biopsies. Economic models such as cost-effectiveness analyses help in determining the incremental cost-effectiveness ratio (ICER) of interventions. Studies have shown varying
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POSNOC & ATNEC Trials Update by Amit Goyal: Investigating Axillary Treatment in Breast Cancer
POSNOC (Positive Sentinel Node) and ATNEC trials are investigating the effectiveness of axillary treatment in women with early-stage breast cancer having metastases in one or two sentinel nodes. Led by Chief Investigator Amit Goyal in the UK, this randomized controlled trial compares adjuvant therap
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Case Study: Pancreatoblastoma with Liver Metastasis in a 23-Year-Old Pregnant Female
A 23-year-old pregnant female presents with abdominal pain, leading to the diagnosis of pancreatoblastoma with liver metastasis. Initial biopsy and imaging confirm the presence of high-grade carcinoma, with treatment involving chemotherapy and stem cell transplant. CT features and a differential dia
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Standard of Care for Peripheral Lesion Assessment in Lung Cancer
The provided guidelines outline the standard care pathway for assessing peripheral lesions in lung cancer patients based on staging CT findings. It includes recommendations for biopsy methods, fitness assessment, PET-CT imaging, and considerations for treatment decisions. The protocol emphasizes tai
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Radiology-Pathology Correlation Case Presentation: Ms. DR - Lung Mass Evaluation
Ms. DR, a 62-year-old female with a history of tobacco use, presents with a right lung mass and possible metastatic disease. Imaging reveals a FDG-avid lung mass suspicious for primary malignancy. After obtaining informed consent, a CT-guided core biopsy is performed, showing cohesive, medium-sized
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Standard of Care for Peripheral Lesion Assessment with Normal Hilar and Mediastinal Appearances
Assessing patients with peripheral lesion on staging CT with normal hilar and mediastinal findings. Further investigation with contrast-enhanced CT is recommended for fitness evaluation and treatment planning. Biopsy methods, diagnostic criteria, and considerations for nodules and nodal staging are
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General Clinical Research Unit (GCRU) Services Overview
The General Clinical Research Unit (GCRU) under Ridiane Denis offers support for a wide range of active protocols in various research areas like endocrinology, Alzheimer's, oncology, and more. GCRU provides clinical and laboratory services including sample processing, infusion, biopsy, urine analysi
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Comprehensive Pre-Treatment Assessment for Chronic Hepatitis C in Adults
Core trainers in CPG management of Chronic Hepatitis C in adults must focus on pre-treatment assessment to identify co-morbidities, assess liver status, determine fibrosis severity, and conduct necessary blood investigations. Utilizing non-invasive methods for liver fibrosis assessment is crucial fo
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Dermatological Case Presentation: Clinical Findings and Pathology Results
Detailed presentation materials for a dermatological case including case history, clinical skin examination findings, clinical photographs, histopathology results, and additional workup details. Emphasis on the importance of non-identifying information in presentations for discussion at the CDS Quar
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Evolution of Liver Biopsy in Children: ESPGHAN Position Paper
Liver biopsy plays a crucial role in diagnosing, staging, and prognostic evaluation of liver diseases in children. Indications for liver biopsy include diagnostic, prognostic, and monitoring purposes. Specific scenarios like neonatal cholestasis and progressive familial intrahepatic cholestasis requ
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Comprehensive Guide to Neurological Examination in Dogs and Cats
Neurological examination in dogs and cats is crucial for diagnosing nervous system disorders. This guide covers the recording of history, general and detailed clinical examinations, examination of CSF, radiographic examination, EEG, and brain biopsy. It includes assessing history, mental state, move
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Excised Biopsy Tract Histology for Primary Bone Tumours: Necessity of Excision Examined
Investigating the necessity of excising biopsy tracts in primary bone tumours, this study analyzed 278 patients over a span of two years. Findings indicated conflicting evidence regarding the risk of malignant seeding in biopsy tracts, with only one patient showing histological evidence of seeding.
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Skin Cancer Management Guidelines - Surgical Approach and Follow-Up Protocol
Guidelines for managing suspicious pigmented lesions and invasive melanoma, with detailed protocols for excision margins, lymph node biopsy, staging scans, and follow-up care. Emphasis on surgical management, sentinel lymph node biopsy, medical oncology consultation, and shared follow-up with plasti
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Advantages of Blastocyst Transfer in Assisted Reproduction
Blastocyst transfer in assisted reproduction offers several advantages, including improved embryo selection, better synchronization with the female endometrium, reduced uterine contractions, and higher implantation rates. It also allows for cleavage stage embryo biopsy, decreases the risk of multipl
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Histiocytic Neoplasia in the Heart: A Rare Case Report
A 3-year-old girl presented with persistent fever, leading to the discovery of a cardiac mass diagnosed as histiocytic neoplasia through imaging and biopsy. Primary cardiac tumors are rare in children, with benign tumors being more common. Histiocytic sarcomas are malignant neoplasms with characteri
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Canine Mammary Neoplasms: Overview and Management by Dr. Ramesh Tiwary
Canine mammary neoplasms, including benign adenomas and malignant carcinomas, are common in intact female dogs. This article discusses the clinical signs, diagnosis methods like FNAC and biopsy, WHO clinical staging system, and the importance of palpating regional lymph nodes for prognosis assessmen
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Approach to Dysphagia: Esophageal Cancer & Achalasia Cases
This presentation covers the diagnostic approach and management strategies for dysphagia in a 65-year-old patient presenting with symptoms such as odynophagia, cough, hoarseness, and lymphadenopathy. It discusses the use of CBC, CXR, ECG, upper GI endoscopy, CT, and biopsy in assessing the location,
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Malignant Melanoma of Left Eye Lower Lid - Case Presentation
A rare case of malignant melanoma affecting the lower lid of a 50-year-old female is discussed in this e-poster. The lesion, with characteristic pigmentation and irregular borders, was successfully diagnosed through incision biopsy and histopathological examination. The patient underwent wide excisi
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Inflammatory Bowel Disease Case Study: Diagnostic Challenges and Treatment Decision
A 56-year-old male with a history of inflammatory bowel disease presented with severe symptoms necessitating hospitalization. Despite steroid therapy, lack of improvement led to consideration of a total colectomy. Colonoscopy and biopsy results favored ulcerative colitis over Crohn's disease. This c
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Evaluation of Low-Grade Fever and Bone Pain in a 16-Year-Old Female Patient
A 16-year-old female presented with low-grade fever and bone pain persisting for 7 months. With elevated CRP and ESR levels, a bone biopsy has been requested to investigate the underlying cause. Blood cultures and rheumatologic workup were negative, and results are pending. Further evaluation is ess
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16-Year-Old Female with Bone Pain and Fever: Diagnostic Evaluation
A 16-year-old female presents with low-grade fever and bone pain persisting for 7 months. Elevated CRP and ESR levels, negative blood cultures, and inconclusive rheumatologic work-up prompt a bone biopsy. Results are pending diagnostic investigation and further management for the underlying cause.
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Laboratory Diagnosis of Parasites: Methods and Clinical Specimens
Laboratory diagnosis of parasitic infections involves techniques such as demonstration of parasites, immunodiagnosis, and molecular biological methods. Clinical specimens for diagnosis include blood, urine, genital specimens, sputum, and tissue biopsy/aspiration. Chyluria, a condition with milky whi
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