Insights into the Katz ESI R01 Award Program

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The Katz ESI R01 Award Program, led by Dr. Stephen I. Katz, offers substantial research project awards for Early Stage Investigators without the need for preliminary data. The program emphasizes new research directions and prohibits the use of unpublished data. Applicants must focus on novel approaches and explain how their proposed direction is innovative. The program offers two funding opportunities, one for studies without clinical trials and another for basic experimental studies involving humans.

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Katz ESI R01 Award Program Katz ESI R01 Award Program

Stephen I Katz, M.D., Ph.D. Stephen I. Katz, M.D., Ph.D. NIAMS Director from 1995-2018 Profoundly dedicated to mentoring the next generation of scientists and training early career scientists

Katz ESI R01 Award Concept Advisory Council to the Director Working Group on the Next Generation Researchers Initiative Workgroup (ACD NGRI) recommended: - Expand pathways for funding ESIs through programs that do not require preliminary data - The applicant .. could branch out into a new line of research

Key Features of Katz ESI Award Originated in the recommendations of the ACD NGRI Workgroup Substantial/significant R01-equivalent research project award for Early Stage Investigators New research direction for PI Preliminary data not allowed

Preliminary Data Not Allowed Unpublished data not allowed Apps may include only - Published data or data from preprints that have a Digital Object Identifier (DOI) - Data must be labeled and cited adjacent to each occurrence within application and must be presented unmodified from the original published format The data should be unambiguously identified as published through citation that includes the DOI. All data and figures must be clearly and unambiguously identified as published by providing citation(s) Applications containing unpublished data will be withdrawn without review

New Research Directions Can rely on the applicant s prior work and expertise as its foundation Should not be an obvious or incremental advancement, expansion or extension of a previous research effort New approach, methodology, technique, discipline, target, paradigm Applicants must explain how proposed direction is new to them New Research Directions will be its own attachment

Two Katz FOAs For studies that do not involve clinical trials: - PAR-21-038: Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) For studies that include Basic Experimental Studies with Humans (BESH): - PAR-20-039: Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required) It is important to check which NIH ICs are signed onto each FOA

Peer Review and Budget Considerations Applications will be reviewed at Center for Scientific Review Application budgets are not limited but need to reflect the actual needs of the proposed project Applicants requesting $500,000 or more in direct costs in any year (excluding consortium F&A) must contact a Scientific/ Research Contact at least six weeks before submitting the application to obtain approval from the funding agency prior to their application submission.