Journey to Understanding Disease Causes
Louis Pasteur's advancements in microbiology, from the discovery of microorganisms by Leeuwenhoek to the establishment of germ theory, revolutionized our understanding of disease causation. Through improved microscopes and experiments, Pasteur's work linked microorganisms to disease, setting the stage for further research by scientists like Robert Koch.
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Beliefs about disease in19th Century People knew there was a link between dirt and disease, but could not explain the link. People explained disease as seeds bad seeds in the air known as miasma. 1850s &1860s breakthrough in the cause of disease.
Step 1: Discovery of Micro- organisms Anthony Van Leeuwenhoek made one of the earliest microscopes. Discovered micro- organisms which he called animalcules. Microscopes not as good as today.
Step 2: Improved microscopes 1800s purer glass produced = better lenses for microscope. 1830 Joseph Lister develops a microscope which can magnify x1000
Step 3: Louis Pasteurs germ theory Old Theory: spontaneous generation micro-organisms are the result of decaying matter. New Theory: germ theory micro-organisms cause decaying matter. Pasteur showed you could kill the micro- organisms by applying heat - PASTEURISATION.
Step 4: Germ theory vs spontaneous generation Pasteur now had to prove his theory. In competition with French scientist Pouchet. Conducted an experiment showing that microbes in the air caused decay. 1861 published his germ theory
Step 5: Linking micro-organisms to disease Pasteur showed micro-organisms made wine and beer go bad. Could germs cause disease? Another experiment! Proved that a micro-organism was causing disease in silk worms.
Step 6: Proving the link between bacteria and human disease. Pasteur never showed the link between bacteria and human disease. This was left to Robert Koch
Your Task You need to create a flow chart with the title 6 steps to discovering the causes of disease. Use the slides to help you. For each step you must explain how this helped to discover the cause of disease. You cannot use more then three sentences per step. Additional information can be found on p.128 - 129 of the textbook.
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