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Monkey Pox shares key characteristics with other rashes like Varicella-Zoster (Shingles), Herpes Simplex Virus (HSV), and Contact Dermatitis. Understanding the differences is crucial for accurate diagnosis and proper infection prevention strategies.
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Monkey Pox Versus Other Common Rashes Infection Prevention & Control
Monkey Pox Monkey Pox Photos- https://www.cdc.gov/poxvirus/monkeypox/clinicians/clinical- recognition.html Key Characteristics: Rash that may be located on or near the genitals (penis, testicles, labia, and vagina) or anus (butthole) but could also be on other areas like the hands, feet, chest, face, or mouth. Lesions are deep-seated, firm, or hard and well-circumscribed. Lesions described as painful until they become crusty and/or itchy Lesions may umbilicate or become confluent and progress into scabs New lymphadenopathy If you have a patient with monkeypox, test for routine sexually transmitted diseases including syphilis. If your patient has a positive test for a STI, do not assume monkeypox is ruled out. If rash is present, test for monkey pox also if secondary syphilis, HSV or primary HIV infection is suspected. Infection Prevention & Control
Varicella- Zoster (Shingles) Varicella Photos: https://www.immunize.org/photos/chickenpox-photos.asp Key Characteristics: Rash almost never appears on soles/palms No lymphadenopathy Crops of lesions in different stages monkeypox viruses tend to have all lesions in same stage of development Rash usually involves the central portion of the body Patients do not appear as ill as monkeypox patients Infection Prevention & Control
Herpes Simplex Virus (HSV) HSV Photos: https://www.immunize.org/photos/zoster-photos.asp Key Characteristics: Typically, only involve oral and genital regions Minimal symptoms with recurrences compared to monkeypox May present with fever and muscle aches Infection Prevention & Control
Contact Dermatitis Contact dermatitis Photos: https://www.medicinenet.com/image- collection/nickel_contact_dermatitis_picture/picture.htm Key Characteristics: Rash develops where skin had contact with a substance Generally, no systemic symptoms (fever, muscle aches) More itch/burn than pain Typically, weepy (oozing) May have blisters (but typically in different stages) May have lymphadenopathy Infection Prevention & Control
Syphilis Syphilis Photos: https://www.cdc.gov/std/syphilis/images.htm Key Characteristics: Initial chancre may present on any mucosal membrane (usually oral, anal) or on genitals o Chancre typically painless monkeypox lesions are painful Rash may appear anywhere on body, and can mimic many other diseases Infection Prevention & Control
