Understanding Transcription and RNA Processing in Molecular Biology

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Explore the intricate processes of transcription and RNA processing in molecular biology, delving into the types of RNA molecules, the differences between DNA and RNA, RNA polymerase enzymes, transcription factors, and the preinitiation complex. Visual aids and detailed descriptions help elucidate the essential components of gene expression regulation.

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Presentation Transcript

  1. Chapter 10: Transcription and RNA Processing 10.1 Types of RNA

  2. DNA vs RNA

  3. DNA vs RNA

  4. Translation

  5. Micro RNA (miRNA)

  6. Types of RNA Molecules

  7. Chapter 10: Transcription and RNA Processing 10.2 RNA Polymerase Enzymes

  8. Transcription Initiation

  9. RNAP

  10. Eukaryotic RNA Polymerase Enzyme

  11. Chapter 10: Transcription and RNA Processing 10.3 Transcription Factors and the Preinitiation Complex

  12. General Transcription Factors

  13. Preinitiation Complex (PIC)

  14. TBP T TATA Box B Binding P Protein

  15. TBP T TATA Box B Binding P Protein

  16. TBP T TATA Box B Binding P Protein

  17. TBP T TATA Box B Binding P Protein

  18. TBP T TATA Box B Binding P Protein

  19. Preinitiation Complex

  20. Enhancer Elements

  21. Chapter 10: Transcription and RNA Processing 10.4 Transcription Elongation and Termination

  22. Prokaryotic Transcription Elongation

  23. Prokaryotic Transcription Elongation

  24. Prokaryotic Transcription Elongation

  25. Transcriptional Backtracking Figure from: Sharma, A.K. and Chowdhury, D. (2012) Biophys Rev & Let 07:03n04

  26. Gre Factors to the Rescue!

  27. Prokaryotic Transcription Termination

  28. Prokaryotic Transcription Termination The Rho Protein

  29. Eukaryotic Termination

  30. Chapter 10: Transcription and RNA Processing 10.5 Processing of RNA

  31. Prokaryotic mRNA Processing

  32. Eukaryotic RNA Processing

  33. 3- Polyadenylation

  34. The Location of Polyadenylation

  35. 5- CAP Formation

  36. Decapping Enzymes and Degradation Figure from: DanyilGrybchuk

  37. Intron Splicing

  38. Intron Splicing

  39. Two Transesterification Reactions

  40. Two Transesterification Reactions

  41. Two Transesterification Reactions

  42. Two Transesterification Reactions

  43. Two Transesterification Reactions

  44. Intron Splicing

  45. Intron Splicing

  46. Intron Splicing

  47. Intron Splicing

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