Understanding Benzene and Its Derivatives: Methods, Properties, and Reactions

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Explore the methods for preparing benzene, understand its chemical properties and reactions including halogenation, nitration, sulfonation, Friedel-Crafts alkylation, and acylation. Dive into carbon-carbon bond formations and substitution reactions in aromatic compounds.


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  1. Benzene and its derivatives Dr. Zamir G Khan Assistant Professor H R Patel Institute of Pharmaceutical Education and Research Shirpur, Dist. Dhule, (M.S) 425405

  2. Learning Outcomes After completion of this topic student shall be able to Enumerate methods for preparation of benzene Explain chemical properties / reactions of benzene Describe chemical reactions like; Halogenation, Nitration, sulfonation Describe chemical reactions like; Friedal Crafts alkylation, Friedal Crafts acylation 29-09-2024 2

  3. Methods for preparation of benzene NaOH +CaO From sodium salt of benzoic acid From benzene sulfonic acid H3O+, From benzene diazonium salts H3PO2 29-09-2024 3

  4. Methods for preparation of benzene Zn dust From Phenol From Grignard reagent Mg ether H2O +Mg(OH)Br 29-09-2024 4

  5. Chemical Properties/ Reactions of benzene The most characteristic reaction of aromatic compounds is substitution at a ring carbon: 29-09-2024 5

  6. Chemical Properties/ Reactions of benzene 29-09-2024 6

  7. Chemical Properties/ Reactions of benzene 2 1 3 Carbon-Carbon Bond Formations: R R Cl 4 5 AlCl3 Arenes Alkylbenzenes 4 29-09-2024 7

  8. Chemical Properties/ Reactions of benzene 29-09-2024 8

  9. Chemical Properties/ Reactions of benzene 29-09-2024 9

  10. Chemical Properties/ Reactions of benzene 29-09-2024 10

  11. Chemical Properties/ Reactions of benzene 29-09-2024 11

  12. Chemical Properties/ Reactions of benzene 29-09-2024 12

  13. Chemical Properties/ Reactions of benzene 29-09-2024 13

  14. Chemical Properties/ Reactions of benzene Bromination-Why not addn of Br2? 29-09-2024 14

  15. Chemical Properties/ Reactions of benzene 29-09-2024 15

  16. Chemical Properties/ Reactions of benzene Nitration 29-09-2024 16

  17. Chemical Properties/ Reactions of benzene 29-09-2024 17

  18. Chemical Properties/ Reactions of benzene 29-09-2024 18

  19. Chemical Properties/ Reactions of benzene 29-09-2024 19

  20. Chemical Properties/ Reactions of benzene 29-09-2024 20

  21. Chemical Properties/ Reactions of benzene 29-09-2024 21

  22. 29-09-2024 22

  23. Chemical Properties/ Reactions of benzene 29-09-2024 23

  24. Chemical Properties/ Reactions of benzene Friedal Craft Acylation 29-09-2024 24

  25. Chemical Properties/ Reactions of benzene Friedal Craft Acylation 29-09-2024 25

  26. Chemical Properties/ Reactions of benzene 29-09-2024 26

  27. Learning Outcomes Summary Enumerate methods for preparation of benzene Explain chemical properties / reactions of benzene Describe chemical reactions like; Halogenation, Nitration, sulfonation Describe chemical reactions like; Friedal Crafts alkylation, Friedal Crafts acylation 29-09-2024 27

  28. Thank you Mr. Z. G. Khan, Assist. Professor, H R Patel Institute of Pharmaceutical Education and Research Shirpur, Dist Dhule (M.S) 425 405 Email: khanzamir.5588@gmail.com Webpage: https://khanzamir5588.wixsite.com/zamir YouTube Channel: https://www.youtube.com/channel/UCsQae74- x4t5iYK02iPRTxA?view_as=subscriber Whatsapp: +91 9890 044 661 29-09-2024 28

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