Structure and Function of a Serous Compound Tubulo-acinar Gland
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It is a compound tubulo acinar gland of serous
secreting nature
The capsule is made up of connective tissue which
divides the gland through its trabeculi into several lobes
and lobules
The glandular adenomeres are made up of Pyramidal
cells with parabasally placed spherical nucleus
The cytoplasm presents eosinophilic cytoplasmic
granules containing enzymes
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The main excretory duct is lined with simple
columnar epithelium
The central lumen of the acini presents
centroacinar cells which are extended epithelial
cells of intercalated ducts
Myoepithelial cells are absent
Irregular connective tissue known as Glisson’s capsule
is covered to its maximum extent by peritoneum
From this capsule the CT descends towards the center
of the gland which are predominated with reticular fiber
These septations divide the parenchyma into roughly
hexagonal lobules
The interlobular septations are quite prominent in pig
and made up of collagen fibers and are least developed
in other animals
The cells of the liver are known as hepatocytes which are
arranged in radiating columns from outer margin of central vein
towards the periphery of the lobule
The hepatic cell column are separated from each other by
sinusoids which start from periphery and opens in the central
vein
The hepatocytes are usually mononucleated cells and nucleus
is spherical and cytoplasm rich in
mitochondria,polyribosomes,ribosomes,lysosomes,SER,lipid
and glycogen granules
The sinusoidal wall is associated with large
stellate shaped phagocytic cells popularly
known as Kuffer’s cells
The space between the sinusoids and
hepatocyte is called space of Disse
A detailed description of a compound tubulo-acinar gland with serous-secreting nature is provided, highlighting its cellular composition, arrangement of ducts, and connective tissue organization. The glandular structure, including adenomeres, centroacinar cells, and myoepithelial cells, is discussed, along with the role of various components within the gland. The presence of Glisson's capsule and the organization of lobules within the parenchyma are outlined, with a focus on interlobular septations. Additionally, the hepatic architecture, hepatocytes' arrangement towards sinusoids, and their cellular characteristics are elucidated.
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Presentation Transcript
It is a compound tubulo acinar gland of serous secreting nature The capsule is made up of connective tissue which divides the gland through its trabeculi into several lobes and lobules The glandular adenomeres are made up of Pyramidal cells with parabasally placed spherical nucleus The granules containing enzymes cytoplasm presents eosinophilic cytoplasmic
The main excretory duct is lined with simple columnar epithelium The centroacinar cells which are extended epithelial cells of intercalated ducts Myoepithelial cells are absent central lumen of the acini presents
Irregular connective tissue known as Glissons capsule is covered to its maximum extent by peritoneum From this capsule the CT descends towards the center of the gland which are predominated with reticular fiber These septations divide the parenchyma into roughly hexagonal lobules The interlobular septations are quite prominent in pig and made up of collagen fibers and are least developed in other animals
The arranged towards The sinusoids vein The is is mitochondria,polyribosomes,ribosomes,lysosomes,SER,lipid and The cells arranged in towards the The hepatic sinusoids which vein The hepatocytes spherical mitochondria,polyribosomes,ribosomes,lysosomes,SER,lipid and glycogen cells of in radiating the periphery hepatic cell which start of the radiating columns periphery of cell column start from the liver liver are columns from of the column are from periphery are known known as from outer the lobule are separated periphery and as hepatocytes outer margin hepatocytes which margin of which are of central are vein central vein lobule separated from and opens from each opens in each other in the other by the central by central hepatocytes are spherical are usually usually mononucleated and mononucleated cells cytoplasm cells and and nucleus rich nucleus and cytoplasm rich in in glycogen granules granules
The stellate known The hepatocyte The sinusoidal stellate shaped known as The hepatocyte is is called sinusoidal wall shaped phagocytic as Kuffer s space called space wall is is associated phagocytic cells Kuffer s cells space space of associated with cells popularly with large popularly large cells between between the of Disse the sinusoids Disse sinusoids and and
