Pharmaceutical Chemistry: A Comprehensive Overview
•
Essentials of Pharmaceutical Chemistry
•
Third edition Donald Cairns
•
BSc, PhD, CSci, CChem, MRPharmS, MRSC
•
Associate Head of School of Pharmacy
•
The Robert Gordon University Aberdeen, UK
Contents
•
Chemistry of acids and bases
•
Partition coefficient and biopharmacy
•
Physicochemical properties of drugs
•
Stereochemistry
•
Drug metabolism
•
Volumetric analysis of drugs
•
Analytical spectroscopy
•
Stability of drugs and medicines
•
Kinetics of drug stability
What is Pharmaceutical
Chemistry?
P
harmaceutical chemistry is the study of drugs, and it involves drug
development. This includes drug discovery, delivery, absorption,
metabolism, and more
.
.
Pharmaceutical chemistry is concerned with the design (drug design) and synthesis of
biologically active molecules.
The aim is to gain new chemical molecules that could enable the discovery of new
pharmaceuticals or optimize already known drug structures, thereby to expand the
portfolio of chemical drugs.
Chemistry of acids and bases
Chemistry is the defining science of pharmacy.
To understand
anything
about a drug
;
–
the synthesis,
the determination of its purity,
the formulation
into a medicine,
the dose given,
the absorption and distribution around
the body,
the molecular interaction of drug with its receptor,
The
metabolism of the drug and,
the elimination of drug from the body
– requires a thorough and comprehensive understanding of the chemical
structure of the drug and how this chemical structure influences the properties
and
behaviour of the drug in the body.
For these reasons, chemistry is
the most important of all the scientific disciplines
contributing to the
understanding of drugs and their actions in the body.
Pharmaceutical chemistry delves into the study of drugs, encompassing their development, discovery, synthesis, absorption, metabolism, and more. It involves the design and synthesis of biologically active molecules to create new pharmaceuticals or enhance existing drug structures. Chemistry plays a pivotal role in comprehending the properties and behavior of drugs in the body, making it a crucial discipline in pharmaceutical sciences.
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Presentation Transcript
Essentials of Pharmaceutical Chemistry Third edition Donald Cairns BSc, PhD, CSci, CChem, MRPharmS, MRSC Associate Head of School of Pharmacy The Robert Gordon University Aberdeen, UK
Contents Chemistry of acids and bases Partition coefficient and biopharmacy Physicochemical properties of drugs Stereochemistry Drug metabolism Volumetric analysis of drugs Analytical spectroscopy Stability of drugs and medicines Kinetics of drug stability
What is Pharmaceutical Chemistry? Pharmaceutical chemistry is the study of drugs, and it involves drug development. This includes drug discovery, delivery, absorption, metabolism, and more.
. Pharmaceutical chemistry is concerned with the design (drug design) and synthesis of biologically active molecules. The aim is to gain new chemical molecules that could enable the discovery of new pharmaceuticals or optimize already known drug structures, thereby to expand the portfolio of chemical drugs.
Chemistry of acids and bases Chemistry is the defining science of pharmacy. To understand anything about a drug; the synthesis, the determination of its purity, the formulation into a medicine, the dose given, the absorption and distribution around the body, the molecular interaction of drug with its receptor, The metabolism of the drug and, the elimination of drug from the body requires a thorough and comprehensive understanding of the chemical structure of the drug and how this chemical structure influences the properties and behaviour of the drug in the body. For these reasons, chemistry is the most important of all the scientific disciplines contributing to the understanding of drugs and their actions in the body.
