Nuclear Medicine Radiotracers Distribution

Nuclear Medicine Radiotracers:
Distribution and Physical Properties
PART 2
Jacob Dubroff MD PhD
Jennifer Schroeder, MD
Nuclear Medicine Jeopardy
If you are doing this at
home, the answers are in
the slide notes, but the
links on the main page only
work in presentation
mode.
The purple arrow at the
bottom on the picture
slides will take you back to
this page
Insert Text for Question
Category 1 – 10 points
Insert Text for Question
Category 1 – 20 points
Insert Text for
Question
Category 1 – 30
points
Diagnostic imaging
Insert Text for Question
Category 1 – 40 points
Insert Text for Question
Category 1 – 50 points
Insert Text for Question
Category 2 – 10 points
Insert Text for Question
Category 2 – 20 points
Insert Text for Question
Category 2 – 30 points
Positive
     
 
Negative
Insert Text for Question
Category 3 – 10 points
Insert Text for Question
Category 3 – 20 points
Insert Text for
Question
Category 3 – 30
points
Insert Text for Question
Category 3 – 40 points
Insert Text for
Question
Category 3 –
50 points
Insert Text for Question
Category 4 – 10 points
This is the reason why you have to be careful about SUV measurements of inferior lung lesions
and hepatic dome lesions.
It is also why CT done for the PET is done at quiet breathing so that tidal volume is more
representative of those occurring during PET acquisition. PET acquisition is too long to do
breath hold.
Which is the NAC images?
How to treat/decrease
brown fat (4Bs):
blanket
benzo
beta blockers
brown fat diet- aka
ketogenic
Name two indications for
an FDG PET of the Brain
Insert Text for Question
Category 4 – 50 points
1
st
 FDG-PET/CT
  
1 Week
    
2
nd
 FDG-PET/CT
 
 
only 1 week later
Basic FDG PET diet prep:
NPO preferentially for 6 hours before hand, at least 4 hours.
No short acting insulin for 4 hours before.
Cardiac Nuclear Medicine Imaging
Techniques are principally used to
demonstrate these types of
defects.
NPO preferentially for 6 hours before hand,
at least 4 hours
no short acting insulin for 4 hours before
hand
Please name a SPECT Cardiac Tracer
Tc99m sestamibi
Tc99m tetrofosmin
Thallium 201
Insert Text for Question
Category 5 – 30 points
Positive scan
Negative scan
Please name a 
PET Cardiac Tracer
F18 FDG
Rubidium 82 chloride
Oxygen 15 water
Nitrogen 13 ammonia
FDG Cardiac PET can be 
used to Demonstrate this.
which PET is FDG, top or bottom row? Why?
This is a POST therapy SPECT
Yttrium 90 with half life of 64 hours
What is the MeV of F-18?
What is stochastic effect?
Effects that occur by chance and which may
occur 
without a threshold
 level of dose, whose
probability is proportional to the dose
 and
whose severity is independent of the dose. In
the context of radiation protection, the main
stochastic
 effect is cancer.
What is Linear Energy Transfer
LET: the amount of energy transferred per unit length
traveled
Which type of radiation has the highest LET?
What is the most radiation sensitive phase of the
cell cycle?
M
then G2>G1>S
cell sensitivity is also based on reproductive activity
(parallel) and differentiation (inverse)
What molecules act as modulators of the effects
of indirect radiation?
Water
we are bags of water with tiny bit of DNA- most radiation
act on water which then affects DNA, aka the indirect
What potentiates this process?
What is the max tolerated dose to the marrow?
2 Gy
What is the LD 50/60?
At what dose must you report a sentinel event?
15 Gy
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Explore the distribution and physical properties of radiotracers in nuclear medicine, presented in an engaging format with questions and images related to diagnostic imaging and PET scans. Dive into the world of nuclear medicine with insights from experts in the field.

  • Nuclear Medicine
  • Radiotracers
  • Diagnostic Imaging
  • PET Scans
  • Medical Education

Uploaded on Apr 17, 2024 | 7 Views


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  1. Nuclear Medicine Radiotracers: Distribution and Physical Properties PART 2 Jacob Dubroff MD PhD Jennifer Schroeder, MD

  2. Nuclear Medicine Jeopardy PET peeves I NM Don't know much biology 10 If you are doing this at home, the answers are in the slide notes, but the links on the main page only work in presentation mode. 10 10 20 20 20 30 30 30 The purple arrow at the bottom on the picture slides will take you back to this page 40 40 40 50 50 50 100 100 100

  3. Insert Text for Question Category 1 10 points

  4. Insert Text for Question Category 1 20 points

  5. Diagnostic imaging Insert Text for Question Category 1 30 points

  6. Insert Text for Question Category 1 40 points

  7. Insert Text for Question Category 1 50 points

  8. Insert Text for Question Category 2 10 points

  9. Insert Text for Question Category 2 20 points

  10. Insert Text for Question Category 2 30 points

  11. Positive Negative

  12. Insert Text for Question Category 3 10 points

  13. Insert Text for Question Category 3 20 points

  14. Insert Text for Question Category 3 30 points

  15. Insert Text for Question Category 3 40 points

  16. Insert Text for Question Category 3 50 points

  17. Insert Text for Question Category 4 10 points This is the reason why you have to be careful about SUV measurements of inferior lung lesions and hepatic dome lesions. It is also why CT done for the PET is done at quiet breathing so that tidal volume is more representative of those occurring during PET acquisition. PET acquisition is too long to do breath hold.

  18. Which is the NAC images?

  19. How to treat/decrease brown fat (4Bs): blanket benzo beta blockers brown fat diet- aka ketogenic

  20. Name two indications for an FDG PET of the Brain

  21. Insert Text for Question Category 4 50 points 1st FDG-PET/CT only 1 week later 1 Week 2nd FDG-PET/CT Basic FDG PET diet prep: NPO preferentially for 6 hours before hand, at least 4 hours. No short acting insulin for 4 hours before.

  22. NPO preferentially for 6 hours before hand, at least 4 hours no short acting insulin for 4 hours before hand Cardiac Nuclear Medicine Imaging Techniques are principally used to demonstrate these types of defects.

  23. Please name a SPECT Cardiac Tracer Tc99m sestamibi Tc99m tetrofosmin Thallium 201

  24. Positive scan Insert Text for Question Category 5 30 points Negative scan

  25. Please name a PET Cardiac Tracer F18 FDG Rubidium 82 chloride Oxygen 15 water Nitrogen 13 ammonia

  26. FDG Cardiac PET can be used to Demonstrate this. which PET is FDG, top or bottom row? Why?

  27. This is a POST therapy SPECT Yttrium 90 with half life of 64 hours

  28. What is the MeV of F-18?

  29. What is stochastic effect? Effects that occur by chance and which may occur without a threshold level of dose, whose probability is proportional to the dose and whose severity is independent of the dose. In the context of radiation protection, the main stochastic effect is cancer.

  30. What is Linear Energy Transfer LET: the amount of energy transferred per unit length traveled Which type of radiation has the highest LET?

  31. What is the most radiation sensitive phase of the cell cycle? M then G2>G1>S cell sensitivity is also based on reproductive activity (parallel) and differentiation (inverse)

  32. What molecules act as modulators of the effects of indirect radiation? Water we are bags of water with tiny bit of DNA-most radiation act on water which then affects DNA, aka the indirect What potentiates this process?

  33. What is the max tolerated dose to the marrow? 2 Gy What is the LD 50/60?

  34. At what dose must you report a sentinel event? 15 Gy

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