I2Start Grant Program for MedTech Start-ups in Singapore

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"The I2Start Grant Program is a joint initiative by SMART, NHIC, and Enterprise Singapore aimed at supporting MedTech start-ups in Singapore. With funding up to $250K and a focus on Medical Technologies like life science tools and digital health, the program offers a streamlined funding pathway, reduced paperwork, and access to regulatory and engineering consultants. Eligibility criteria include a Technology Readiness Level of 3 or above and a team composition requirement. The program does not support certain funding criteria like strong intellectual property positions and manufacturing lines. Application is open throughout the year via submission of a Letter of Intent to the Grant Secretariat."


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  1. Innovation to Startup (I2Start) A Joint SMART NHIC Enterprise Singapore Partnership

  2. SMART Innovation Grant - $250K I2START PROGRAM 1 A premium funding program targeted at MedTech start-ups from Singapore public institutions. NHIC Innovation to Develop Grant - $250K 2 The tripartite partnership between NHIC, SMART, and Enterprise Singapore strategically bring together funding and resources to support start-ups. 3 POC/POV Grant up to $750K

  3. VALUE PROPOSITION STREAMLINE FUNDING PATHWAY Alignment of funding criteria across different funding bodies IMPACT BOOTCAMP ECOSYSTEM PARTNERSHIP Bridge project funding gap by creating a seamless funding pathway FUNDED PROJECT TEAM BUSINESS SUPPORT CATALYST PROGRAM Reduced paperwork for applicants Reduced waiting time and the need for subsequent grant application and approval PROJECT MANAGEMENT Project teams able to tap into multiple agencies resources and support REGULATORY CONSULTANT ENGINEERING CONSULTANT

  4. I2START GRANT INFO Eligibility Criteria Grant Frequency Entry: TRL 3* and above Medical Technologies in the following areas; Life science tools Clinical diagnostics Medical device and products Digital health Team with the intent to start-up a company Team must consist of one Clinical PI and Technical PI from public institutions Application is open throughout the year Submission Mode Letter of Intent to be submitted by Lead PI to the I2Start Grant Secretariat at grant@nhic.sg. * Definition: Technology Readiness Level 3 - Initial proof-of-concept demonstrated

  5. I2START FUNDING CRITERIA Funding Criteria I2Start Program does NOT support the following: Strong intellectual property position Preliminary proof of-concept data in in vitro and/or in vivo research/laboratory models Detailed technical and clinical development plan leading to a start-up, highlighting project scope and milestones for each phase Clear and achievable commercial plan outlining the unmet healthcare need, the proposed start-up structure and competitive landscape Incremental or predictable next step in the improvement of existing technology A simple combination of current technologies in a new format Setting up of manufacturing lines Drugs and biologics discovery/development

  6. I2START APPLICATION PROCESS PRESENTATION TO EVALUATION COMMITTEE LETTER OF INTENT SUBMISSION SHORTLISTED FOR GRANT APPLICATION FUNDING DECISION PROPOSAL ENDORSEMENT PROPOSAL SUBMISSION Shortlisted LOI applicants will be invited to submit a formal application. The agencies will jointly engage the team. Proposal evaluation. All applicants will be notified with feedback. Only endorsed applicants will be invited for presentation. Evaluation Committee comprising of funding agencies, investors, and industry experts. Evaluation Committee meet once every quarter. Letter of Intent submission is open throughout the year. Applicants will be notified with feedback within 4 weeks. Feedback by Evaluation Committee. LOA will be issued to successful applicants.

  7. SEAMLESS FUNDING PATHWAY All phase milestones set and approved Letter of Award^ by SMART Followed by Letter of Intent by NHIC Upon meeting Phase 1 milestones, NHIC issues Letter of Award^ Followed by Letter of Intent by Enterprise Singapore Upon meeting Phase 2 milestones, Enterprise Singapore issues Letter of Award^* * Requisites: (1) Incorporate a company (start-up), with key members hired full-time, and (2) License the IPs developed at SMART/ NHIC project phase (Licensing agreement) ^Individual grant terms apply PHASE 1 PHASE 2 PHASE 3 PI must hold a primary appointment in Singapore public institution Team must incorporate a company

  8. Innovation to Startup (I2Start) A premium funding program targeted at aspiring MedTech start-ups from Singapore public institutions http://nhic.sg/web/index.php/our-funding/innovation-to-startup Further enquiries, contact I2Start Grant Secretariat: Dr Michael HO, michael_ho@nhic.sg Dr YEOW Siang Lin, yeow_siang_lin@nhic.sg

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