Hypertension: Causes, Symptoms, and Management

 
Hypertension
 
Åsa Lundgren, Rotary Doctors
October 2022
 
What is blood pressure?
 
The pressure of the circulating
blood on the vessels.
Systolic: When the heart
contracts.
Diastolic: When the heart rests
between two beats.
 
What is high blood pressure/hypertension?
 
>
140/
>
90
Persistently elevated blood pressure in the
arteries.
 Increased pressure on the vessel walls.
Hardening and thickening of the arteries =
stiff arteries.
The heart needs to work harder.
 
 
Why is hypertension dangerous?
 
 
Increased risk för heart disease, including infarction
Increased risk of stroke
Increased risk of hypertensive renal failure
Retinpathy
Vascular dementia
 
Causes of primary (essential) hypertension
Causes of primary (essential) hypertension
 
Hereditary
Overweight
NaCl-consumtion
Stress
Age
Atherosclerosis
Diabetes
 
Secondary hypertension 5-10%
 
Hyperaldosteronism
Medication (steroids, NSAID
etc)
 
Caused by another disease:
Diabetes
Kidney disease
Pregnancy
Endocrine dieseases
 
Symtoms of hypertension
 
Most often no symtoms!
 
Headache
Shortness of breath
Nosebleed
Blurred vision
Buzzing in the ears
 
To measure blood pressure
 
Sit or lay down
5 minutes rest
No coffee or tobacco for 30 min
At least once in both arms
Recheck if high
Pulse? Irregular?
 
What can the patient do?
 
Reduce weight if BMI > 25
Physical activity
Fruits and vegetables
Reduce salt intake
Reduce alcohol
 
When to start medication?
 
>
 180/110 (check again after some rest): Amlodipin
5-10 mg OD. Control after 1-2 days.
When patient has tried diet, physical activity etc and
still….
< 80 years: 
>
 140/90
> 80 years: 
>
 160/90.
If known cardiovascular disease, diabetes, kidney
disease 
>
 130/85
 
Before starting treatment
 
Blood tests: Na, K, creatinine, lipids, HbA1c/fasting B-glucose
Urine dipstick
ECG
 
   Treatment should start even if testing is not available.
 
What to start with?
 
Start with 1-2 from these 3 groups:
Calcium-antagonists (Amlodipin)
Thiaziddiuretics (Hydrochlortiazid)
ACE-inhibitors (Enalapril, Ramipril) och ARB (Losartan)
 
Calcium-antagonists
 
Relaxes the muscles in the vessel walls.
The safest if blood tests can’t be taken.
 
 
Amlodipin 5 – 10 mg OD
Felodipin 5 – 10 mg OD
 
Thiazidduiretics
 
Makes the kidneys get rid of water and salt and widens the small
blood vessels.
Risk: Too high doses can reduse potassium.
 
 
Hydrochlortiazid 12,5 – 25 mg OD
Bendroflumethiazid 2,5 mg OD
 
ACE-inhibitor or ARB
 
Diabetes, heart failure, renal failure.
Widens vessels.
 
Angiotensin converting enzyme inhibitor (enalapril 5 – 20 mg
OD, ramipril, captopril):
Common side-effect: Coughing.
Angiotensin II receptor blockers (losartan 50 – 100 mg OD,
candesartan):
 
 
Follow-up
 
Every month until 
<
140/
<
90 is reached.
Increase doses and add medicines until maximal doses of the
three groups.
 
Then every 3rd – 6th month (WHO).
Yearly (Sweden): Blood tests.
 
 
If <140/<90 is not reached
 
Betablockers 
(metoprolol, atenolol): Blocking the effect of
adrenalin/noradrenalin. Especially when chronic ischemic
heart disease.
Loopdiuretics 
(furosemid): Especially if fluid retention.
Aldosteronantagonists 
(spironolacton)
Alfablockers
 
How to succeed?
 
A well-informed patient!
What medicine should I take?
Why?
Life long medication
What can I do myself?
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Blood pressure is the force of blood against the artery walls. Hypertension, or high blood pressure, can lead to serious health risks like heart disease, stroke, and kidney failure. Primary hypertension may be caused by factors like heredity, obesity, and stress, while secondary hypertension can be due to conditions like kidney disease or pregnancy. Symptoms can be subtle, but it's crucial to monitor blood pressure regularly. Lifestyle changes, such as weight loss, exercise, and a balanced diet, can help manage hypertension effectively.

  • Hypertension
  • Blood pressure
  • Causes
  • Symptoms
  • Management

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  1. Hypertension sa Lundgren, Rotary Doctors October 2022

  2. What is blood pressure? The pressure of the circulating blood on the vessels. Systolic: When the heart contracts. Diastolic: When the heart rests between two beats.

  3. What is high blood pressure/hypertension? >140/>90 Persistently elevated blood pressure in the arteries. Increased pressure on the vessel walls. Hardening and thickening of the arteries = stiff arteries. The heart needs to work harder.

  4. Why is hypertension dangerous? Increased risk f r heart disease, including infarction Increased risk of stroke Increased risk of hypertensive renal failure Retinpathy Vascular dementia

  5. Causes of primary (essential) hypertension Hereditary Overweight NaCl-consumtion Stress Age Atherosclerosis Diabetes

  6. Secondary hypertension 5-10% Hyperaldosteronism Medication (steroids, NSAID etc) Caused by another disease: Diabetes Kidney disease Pregnancy Endocrine dieseases

  7. Symtoms of hypertension Most often no symtoms! Headache Shortness of breath Nosebleed Blurred vision Buzzing in the ears

  8. To measure blood pressure Sit or lay down 5 minutes rest No coffee or tobacco for 30 min At least once in both arms Recheck if high Pulse? Irregular?

  9. What can the patient do? Reduce weight if BMI > 25 Physical activity Fruits and vegetables Reduce salt intake Reduce alcohol

  10. When to start medication? > 180/110 (check again after some rest): Amlodipin 5-10 mg OD. Control after 1-2 days. When patient has tried diet, physical activity etc and still . < 80 years: > 140/90 > 80 years: > 160/90. If known cardiovascular disease, diabetes, kidney disease > 130/85

  11. Before starting treatment Blood tests: Na, K, creatinine, lipids, HbA1c/fasting B-glucose Urine dipstick ECG Treatment should start even if testing is not available.

  12. What to start with? Start with 1-2 from these 3 groups: Calcium-antagonists (Amlodipin) Thiaziddiuretics (Hydrochlortiazid) ACE-inhibitors (Enalapril, Ramipril) och ARB (Losartan)

  13. Calcium-antagonists Relaxes the muscles in the vessel walls. The safest if blood tests can t be taken. Amlodipin 5 10 mg OD Felodipin 5 10 mg OD

  14. Thiazidduiretics Makes the kidneys get rid of water and salt and widens the small blood vessels. Risk: Too high doses can reduse potassium. Hydrochlortiazid 12,5 25 mg OD Bendroflumethiazid 2,5 mg OD

  15. ACE-inhibitor or ARB Diabetes, heart failure, renal failure. Widens vessels. Angiotensin converting enzyme inhibitor (enalapril 5 20 mg OD, ramipril, captopril): Common side-effect: Coughing. Angiotensin II receptor blockers (losartan 50 100 mg OD, candesartan):

  16. Follow-up Every month until <140/<90 is reached. Increase doses and add medicines until maximal doses of the three groups. Then every 3rd 6th month (WHO). Yearly (Sweden): Blood tests.

  17. If <140/<90 is not reached Betablockers (metoprolol, atenolol): Blocking the effect of adrenalin/noradrenalin. Especially when chronic ischemic heart disease. Loopdiuretics (furosemid): Especially if fluid retention. Aldosteronantagonists (spironolacton) Alfablockers

  18. How to succeed? A well-informed patient! What medicine should I take? Why? Life long medication What can I do myself?

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