Fever: Causes, Assessment, and Management in Emergency Medicine

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MR SUNEIL RAMNANI
CONSULTANT IN EMERGENCY MEDICINE
PRINCESS ALEXANDRA HOSPITAL
 
Define Fever
Discuss Causes
Assessment
Investigations
Management
Red Flags and Pitfalls
Summary
 
‘A temporary increase in the core body
temperature above the normal range caused by
elevation of the hypothalamic set point’
No single agreed upper limit for normal
temperature.
Normal core body temperature in healthy
people is 35.6˚c – 38.2˚c (mean 36.8˚c)
In adults, a temperature of 38.3˚c is a fever.
In infants, a rectal temperature of 38˚c is a fever.
A temperature over 41.5˚c is not a true fever.
 
Common complaint – 6% of adult ED
attendances and 20-40% of paediatric
attendances.
Same as Pyrexia!
Rectal temperature is most accurate
measurement.
Generally a response to disease or illness but can
be ‘physiological’.
Can indicate serious or life threatening illness.
No relationship between magnitude of
temperature and severity of illness.
 
Hundreds!
Mostly caused by self limiting viral infections.
Infections are the most common cause
(acutely!). 30-40%
Cause usually apparent in ED. (pneumonia,
UTI etc)
FUO/PUO (fever >38.3˚c documented on
several occasions during a period of more
than 3 weeks with uncertain diagnosis after 1
week of evaluation in hospital).
 
Infections/Infectious diseases 20-40%
Neoplastic/Malignancy 10-30%
Non-infectious Inflammatory diseases (eg
collagen vascular diseases, connective tissue
diseases) 20-35%
Miscellaneous (including drug fever) 10-20%
No diagnosis 20-30%
 
Key to Assessment
Associated Symptoms: Cough, SOB, pain,
dysuria, diarrhoea, weight loss, sweats, rigors,
fever, rash, lumps/itching.
Duration
Ill contacts, pets, animal contacts
Occupation
Travel history
Medication
History/risk of immunocompromise
Sexual History, IVDU
Bites, Cuts, Surgery
 
General appearance: sick Vs well
Vital signs
Subtle mental state changes
Rashes
Skin, eyes, lymph nodes, throat, teeth
Liver and spleen
Occult sites of infection: nose/sinuses
PR exam (prostatitis, perirectal abscesses)
Pelvic exam
Nails, joints, temporal arteries
 
Guided by history and examination.
No tests that are always needed for every patient.
Clinical judgement required.
Consider:
Bloods:
FBC and differential. Blood film.
Renal profile
LFTs
CRP, ESR
VBG
Urine dip
Cultures – urine, sputum, blood, stool.
ECG
CXR
Thick and thin blood films.
 
Other tests for the medics!
Serology/virology (EBV,CMV,HIV),
Rheumatoid factor, ANA, protein
electrophoresis, Mantoux, CT scans,
LP,ECHO.
 
Systemic upset/symptoms
‘Unwell’
Abnormal vitals
Abnormal bloods/investigations (eg 
CRP,
WBC, lactate)
Immunocompromised
Admit/refer the above
 
Depends on the cause
Resuscitate!
Antipyretics?
Antibiotics?
Admission/Followup?
 
Relatively common presentation.
Many causes (not just infections!)
May be serious (but usually not!)
History and examination are paramount
Treat the cause
Admit the ill!
Arrange followup for FUOs
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A temporary increase in core body temperature, aka fever, can be a response to various conditions, both physiological and pathological. It is a common complaint in emergency departments, with infections being a primary cause. Assessment involves looking into associated symptoms, duration, medical history, and more. Key aspects include monitoring vital signs, appearance, and conducting necessary investigations to determine the underlying cause.

  • Fever
  • Emergency Medicine
  • Assessment
  • Infections
  • Management

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  1. MR SUNEIL RAMNANI CONSULTANT IN EMERGENCY MEDICINE PRINCESS ALEXANDRA HOSPITAL

  2. Define Fever Discuss Causes Assessment Investigations Management Red Flags and Pitfalls Summary

  3. A temporary increase in the core body temperature above the normal range caused by elevation of the hypothalamic set point No single agreed upper limit for normal temperature. Normal core body temperature in healthy people is 35.6 c 38.2 c (mean 36.8 c) In adults, a temperature of 38.3 c is a fever. In infants, a rectal temperature of 38 c is a fever. A temperature over 41.5 c is not a true fever.

  4. Common complaint 6% of adult ED attendances and 20-40% of paediatric attendances. Same as Pyrexia! Rectal temperature is most accurate measurement. Generally a response to disease or illness but can be physiological . Can indicate serious or life threatening illness. No relationship between magnitude of temperature and severity of illness.

  5. Hundreds! Mostly caused by self limiting viral infections. Infections are the most common cause (acutely!). 30-40% Cause usually apparent in ED. (pneumonia, UTI etc) FUO/PUO (fever >38.3 c documented on several occasions during a period of more than 3 weeks with uncertain diagnosis after 1 week of evaluation in hospital).

  6. Infections/Infectious diseases 20-40% Neoplastic/Malignancy 10-30% Non-infectious Inflammatory diseases (eg collagen vascular diseases, connective tissue diseases) 20-35% Miscellaneous (including drug fever) 10-20% No diagnosis 20-30%

  7. Key to Assessment Associated Symptoms: Cough, SOB, pain, dysuria, diarrhoea, weight loss, sweats, rigors, fever, rash, lumps/itching. Duration Ill contacts, pets, animal contacts Occupation Travel history Medication History/risk of immunocompromise Sexual History, IVDU Bites, Cuts, Surgery

  8. General appearance: sick Vs well Vital signs Subtle mental state changes Rashes Skin, eyes, lymph nodes, throat, teeth Liver and spleen Occult sites of infection: nose/sinuses PR exam (prostatitis, perirectal abscesses) Pelvic exam Nails, joints, temporal arteries

  9. Guided by history and examination. No tests that are always needed for every patient. Clinical judgement required. Consider: Bloods: FBC and differential. Blood film. Renal profile LFTs CRP, ESR VBG Urine dip Cultures urine, sputum, blood, stool. ECG CXR Thick and thin blood films.

  10. Other tests for the medics! Serology/virology (EBV,CMV,HIV), Rheumatoid factor, ANA, protein electrophoresis, Mantoux, CT scans, LP,ECHO.

  11. Systemic upset/symptoms Unwell Abnormal vitals Abnormal bloods/investigations (eg CRP, WBC, lactate) Immunocompromised Admit/refer the above

  12. Depends on the cause Resuscitate! Antipyretics? Antibiotics? Admission/Followup?

  13. Relatively common presentation. Many causes (not just infections!) May be serious (but usually not!) History and examination are paramount Treat the cause Admit the ill! Arrange followupfor FUOs

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