CO Poisoning Safety Scenario and Prevention Guidelines

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Your lab mate appears pale and unwell after working with CO. Understand the symptoms of CO poisoning, the binding affinity of CO to hemoglobin, and the necessary course of action for prevention and response. Stay vigilant in detecting CO, ensuring proper ventilation, and taking immediate action in case of poisoning incidents.


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  1. Safety Scenario CO POISINING

  2. Safety Scenario Your lab mate looks pale and expresses that he/she is not feeling very well. Shortly before that, he/she was doing CO additions. What shold you do?

  3. Symptoms CO binds ~200 times stronger than O2 Half life is 4-6 hours under normal conditions A heme unit of human carboxyhaemoglobin, showing the carbonyl ligand (CO) at the apical position, trans to the histidine residue. https://en.wikipedia.org/wiki/Carboxyhemoglobin

  4. Course of action CO Poising Prevention Keep CO detectors near CO tanks Ensure chemistry is done in a properly ventilated fume hood Work with other people around Potential Poising Response Remove victim from the environment to fresh air Call 911 Pay close attention to their vital signs Use CPR if necessary

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