Viruses interact with host cells in various ways, encoding genes that manipulate cell functions for their benefit. These interactions can range from benign to lethal outcomes. Factors influencing these interactions include viral factors, cellular responses, and the presence of virulence factors. Dif

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Bacterial pathogenesis involves the ability of certain bacteria to cause disease by attributes such as transmissibility, adherence, motility, invasion, and toxigenicity. Pathogens can exploit host defenses, while virulence determines the severity of infection. Learn about opportunistic pathogens, no

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The research conducted by Prof. Jishu Shi and his team at Kansas State University delves into the safety and efficacy testing of experimental African Swine Fever (ASF) vaccines using pigs as the model. Various vaccines, including DNA vaccines and live attenuated viruses, were tested against differen

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Bacteria are single-celled prokaryotic organisms with a simple body design. Their structure includes layers such as the extramural layer, surface appendages like flagella and pili, cell envelop with a cell wall and cytoplasmic membrane, and cytoplasmic inclusions. The capsule and slime layer play es

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Explore the algorithms for identifying Salmonella and Shigella, their antigenic structures, virulence factors, pathogenesis, clinical features, and management concepts. Understand the characteristics, transmission, and prevention strategies for these gastrointestinal pathogens.

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This article discusses the morphology of both Gram-positive and Gram-negative bacteria, highlighting examples of different arrangements and shapes. It also explores the structure and functions of bacterial cell walls, emphasizing the role of teichoic acids in Gram-positive cell walls. Additionally,

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Influenza viruses belong to the Orthomyxoviridae family and are major contributors to respiratory epidemics and pandemics. They consist of three genera - Influenza A, B, and C - with distinct morphological characteristics and genetic makeup. By exploring the properties, classification, and morpholog

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In microbiology, the host-parasite relationship is crucial for understanding diseases caused by pathogens. This lecture covers definitions of terms like pathogenicity, pathogen, disease, resistance, susceptibility, infection, virulence, and transmissibility. It also delves into the division of host

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Fowl cholera, a septicaemic disease affecting birds, is caused by Pasteurella multocida. It can affect all species of birds, with older birds more susceptible. The disease can spread through carrier birds, excretions, carcasses, and even rats. The virulence factors, clinical signs, and forms of the

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Infectious Diseases class focuses on various topics including Antibiotic Stewardship Practices, Community-Acquired Infections, Gram-Positive and Gram-Negative Bacteria, Spirochetal Diseases, Diseases Caused by Bacterial and Viral Infections, HIV/AIDS, Fungal and Parasitic Infections. The class also

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Yersinia pestis, the causative agent of the infamous Black Death, is a Gram-negative coccobacilli bacterium. It is transmitted through fleas and affects lymph nodes, causing bubonic plague. This article explores its general characteristics, pathogenesis, virulence factors, laboratory diagnosis, and

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Viral infection involves a replicative cycle within the host, leading to a range of cellular responses from no apparent effect to disease. Factors such as virulence genes, host characteristics, and viral genome influence the pathogenicity and virulence of a virus. The process includes entry into the

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The pathogenesis of infectious diseases involves the development of a disease caused by a pathogen, with phases like incubation, prodromal, illness, and convalescent periods. Infections can be localized or systemic, acute, subacute, or chronic. Differentiating signs and symptoms, recognizing latent

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Mycoplasma infections, caused by species like Mycoplasma gallisepticum and Mycoplasma synoviae, are common in poultry, particularly affecting turkeys and chickens. These infections lead to respiratory issues, sinusitis, and reduced production rates. Learn about transmission, clinical findings, and v

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The genus Pseudomonas, specifically P. aeruginosa, is a well-known opportunistic pathogen found in diverse ecological niches. This bacterium, commonly associated with disease conditions in animals and humans, exhibits unique growth characteristics, pigment production, and virulence factors. Its adap

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This presentation explores the transfer of foreign DNA into bacteria, discussing mechanisms such as conjugation, transduction, and transformation. It delves into the significance of Mobile Genetic Elements (MGEs) like plasmids, bacteriophages, and transposons in bacterial virulence and pathogenesis.

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Columnaris disease, also known as Saddleback disease, is a common bacterial infection in fish that is often brought about by poor handling and high stress levels. This disease manifests as tail and fin rot, leading to rapid fish mortality. The causative organism, Cytophaga (formerly Flexibacter), is

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Corynebacterium diphtheriae is a non-spore forming Gram-positive bacillus responsible for causing diphtheria in humans. This bacterium, particularly C. diphtheriae, is known for producing a potent exotoxin called diphtheria toxin, which blocks protein synthesis and leads to serious complications suc

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The Enterobacteriaceae family comprises a diverse group of gram-negative rods commonly found in the gut of humans and animals, known for causing various diseases. Key members include Escherichia coli, Shigella, Salmonella, Klebsiella, and more. They are facultative anaerobes, ferment glucose, lack c

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Cryptococcosis is a fungal infection caused by Cryptococcus neoformans, affecting immunocompromised individuals. The disease presents with various clinical features, including pulmonary and extrapulmonary manifestations. Laboratory diagnosis involves examining specimens such as serum and CSF for the

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Porcine Reproductive & Respiratory Syndrome (PRRS) is caused by an RNA virus from the Arteriviridae family, susceptible to environmental factors like temperature, pH, and exposure to detergents. The virus exhibits genomic variability, leading to different levels of virulence and clinical symptoms in

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Neisseria gonorrhoeae, also known as gonococcus, is a bacterial pathogen responsible for gonorrhea. The virulence factors of N. gonorrhoeae include pili/fimbriae for adhesion, outer membrane proteins like Porin for protection, opacity-associated protein for adhesion to neutrophils, and more. Clinica

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A phase 1 clinical trial is underway for a Tat.Oyi-based therapeutic vaccine targeting the virulence factor Tat in HIV. Tat plays a crucial role in viral gene expression and immune system modulation. Inhibiting Tat could disrupt the viral life cycle, block virion release, and potentially reactivate

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Explore the characteristics, structure, gene functions, replication process, and virulence factors of Orthomyxoviruses, specifically focusing on the diverse types of Influenza viruses and their impact on human health. Learn about the group-specific and type-specific antigens, as well as the replicat

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