This UK-wide clinical trial aims to assess the effectiveness of early peripheral norepinephrine infusion in adult patients with septic shock. The study will compare the impact on mortality and other outcomes of targeting a mean arterial pressure (MAP) above 65mmHg within the first 48 hours of admiss

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This presentation discusses the pathophysiology of hypotension in neonates, the role of vasopressors and sedation in neonates with HIE, and the cardiovascular and pulmonary vascular effects of therapeutic hypothermia. It emphasizes the importance of a pathophysiology-based approach to managing vasop

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There are various strains of coronavirus with Sars-cov-2 causing COVID-19. The virus is transmitted through droplets and has an incubation period of 2-14 days. Clinical features range from mild illness to critical disease with a fatality rate of 2.3-5%. Criteria for ICU admission include the need fo

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