Somatic mutations - PowerPoint PPT Presentation


Understanding DNA Mutations and Their Types

DNA mutations are changes in the DNA molecule that can lead to permanent alterations in the base sequence of daughter DNA. Causes include uncorrected errors, as well as damage from oxidative deamination, radiation, and chemicals. The types of mutations include point mutations, insertion mutations, d

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Addressing Functional Somatic Disorders in Patient Safety Rounds

Explore the burden of functional somatic symptoms in NS Health, delve into emotional factors contributing to somatic symptoms, and learn about evidence-based short-term talking therapy for functional somatic disorders. Gain insights from reference materials and data on unexplained symptoms and emerg

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Somatic Exercises for Anxiety - trinexpharmacy.com

Somatic Exercises For Anxiety against an invisible enemy. Itu2019s exhausting, and often, traditional methods of managing it donu2019t always work. This is where somatic exercises come in. But what exactly are somatic exercises? Contact : 1 (747) 209 u2013 3649 E-mail : sales@trinexpharmacy.com

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Different Methods of Genetic Modification in Plants

Genetic modification in plants can occur through natural selection, selective breeding, and induced mutations. Natural selection involves breeding compatible species to create offspring with desired traits, while selective breeding is a multi-generational process to breed organisms with specific cha

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Understanding Inheritance of Traits Through Blue Skin Case Study

Assessing genetic inheritance and mutations using a case study of a boy with blue skin. The scenario highlights how genes control traits, the random assortment of chromosomes in offspring, and the impact of mutations on protein function. Students analyze karyotypes to infer genetic differences betwe

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Complex Case Study: Chronic Pain and Somatic Symptom Disorder

Michelle Adams, a 51-year-old hairdresser, presents with severe chronic back pain following a traumatic incident. Despite various treatments and medications, her pain persists, leading to distress and functional impairment. Her symptoms align with Somatic Symptom Disorder (SSD) with predominant pain

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Understanding Mutations: Types, Characteristics, and Examples

Mutations are changes in the genetic material that can affect an organism's traits. This article explores gene mutations, their historical background, characteristics, kinds of mutations like spontaneous and induced, somatic and germinal mutations, and conditional lethal mutations. It also covers ge

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Understanding Evolution by Natural Selection

Explore the concepts of species, mutation, Darwin's theory of evolution, and the role of genetic variation through mutations. Learn how mutations can lead to rapid changes in species and why a wider variety of genes in a gene pool benefits a population. Delve into the effects of mutations on individ

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Understanding Mutations in DNA and Their Effects

Mutations in DNA are changes that can occur in body cells or gametes, leading to alterations in the genetic code. Not all mutations are harmful, but they can impact protein structure and function. Different types of mutations, such as substitutions, insertions, and deletions, can result from various

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Understanding Non-Transfusion-Dependent Thalassemia

Delve into the complexities of Non-Transfusion-Dependent Thalassemia as explained by Dr. Ashutosh Lal, MD, from the Northern California Thalassemia Center at UCSF Benioff Children's Hospital Oakland. Explore the various Thalassemia syndromes, patient profiles, causes, and transfusion requirements as

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Understanding Somatic Symptom Disorders, Conversion Disorders, and Dissociative Disorders

Somatic symptom disorders manifest as physical symptoms without apparent cause, while conversion disorders involve specific physical symptoms incompatible with medical conditions. Illness anxiety disorder involves interpreting normal sensations as disease symptoms. Dissociative disorders lead to a s

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Pediatric Patient with DIPG/DMG and Genetic Mutations

This case study presents a 0.5-year-old patient diagnosed with Diffuse Intrinsic Pontine Glioma (DIPG) and Diffuse Midline Glioma (DMG) with genetic mutations in H3F3A and TP53. The patient has not undergone prior treatment and is at WHO grade IV stage. Images of tissue samples and stains are provid

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Understanding Genetics: Mutations, Chromosomal Aberrations, and Genetic Engineering

Genetic mutations can be harmless, harmful, or beneficial, leading to variations within a species. Examples of gene mutations and chromosomal aberrations, like Trisomy 21, illustrate genetic abnormalities. The increase in Down Syndrome cases with maternal age highlights a maternal age effect. Geneti

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Understanding Microbial Genetics and Mutations in Organisms

Explore the world of microbial genetics with Dr. Abhishek Thakur, an Assistant Professor specializing in Microbial Genetics at the College of Fisheries, Kishjanganj, BASU, Patna. Learn about important concepts such as strains, clones, genome, phenotype, genotype, genes, genetic recombination, and mu

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Understanding Somatic Symptom and Related Disorders

Exploring the key features, diagnostic criteria, contributing factors, and management principles of Somatic Symptom and Related Disorders. This comprehensive guide covers the clinical manifestations, co-morbidities, and treatment approaches associated with these disorders, shedding light on somatic

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Understanding Mutations in Biology

A mutation in biology refers to changes in the nucleotide sequence of an organism's genome. These alterations can either be harmful, leading to conditions like cancer, or beneficial, such as providing antibiotic resistance. Mutations can occur in somatic cells or gametes, affecting both the individu

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Understanding Mutation and Polyploidy in Genetics

Mutation is a sudden hereditary change in an organism's genetic makeup, leading to variations in offspring. This article delves into the history, types, and causes of mutations, featuring significant discoveries by scientists like De Vries and Morgan. It also explores the concept of spontaneous muta

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Understanding Gene Mutations in Molecular Biology

Gene mutations play a significant role in molecular biology, leading to alterations in DNA sequences that can impact offspring. These mutations can arise spontaneously or be induced by various factors, such as mutagens. Understanding gene mutations is crucial for comprehending the genetic basis of c

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Understanding Population Genetics and Allele Frequency Changes

Population genetics explores how allele frequencies change within populations due to factors like mutations, migration, genetic drift, nonrandom mating, and natural selection. Mutations introduce new variations, migration affects gene flow, genetic drift causes random allele loss, and examples like

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Understanding Somatic Symptom Disorder and Related Disorders

This educational material delves into Somatic Symptom Disorder, Factitious Disorder, and Malingering, emphasizing the importance of accurate diagnosis and management. It explores various aspects, including symptoms, classifications, and implications in bridging physical and mental health. The conten

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Understanding Gene Mutations and Their Impact on DNA Sequences

Gene mutations are changes in the nucleotide sequence of DNA, leading to potential amino acid alterations in proteins. These mutations can occur due to replication errors or external factors like chemicals and radiation. Different types of mutations, such as base substitutions, transitions, transver

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Breakthrough Cancer Therapy in India: Selpercatinib 40 80 mg for RET Mutations

Selpercatinib 40 & 80 mg is an innovative targeted therapy designed to inhibit RET gene mutations, providing a highly precise treatment option for patients with non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC), and RET fusion-positive thyroid cancers. Now available as Selpercatinib

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Understanding Genes, Chromosomes, Alleles, and Mutations in DNA

Explore the intricate world of genetics through genes, chromosomes, alleles, and mutations. Delve into the fundamental structures of DNA, such as nucleosomes and eukaryotic chromosomes. Gain insights into key genetic terms like genes, alleles, and genome composition. Learn about mutations, including

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Understanding Chromosomal Aberrations and Mutations in Genetics

Chromosomal aberrations and mutations are key events that can alter the genetic structure of organisms. They can lead to numerical abnormalities like aneuploidy and structural abnormalities such as ring chromosomes and chromosome fragments. Understanding these variations in chromosomes is crucial in

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Understanding Mutations: Types and Effects

Explore the world of mutations in this informative content covering topics such as how superheroes like Cyclops, Hulk, and Spiderman acquired their powers, the different types of mutations including small-scale mutations like substitution, deletion, and insertion, as well as large-scale mutations af

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Detection of Mutations in EGFR in Circulating Lung Cancer Cells: Study on SARMS Assay and CTC-Chip

This study by Shyamala Maherswaran, Ph.D., and team focuses on characterizing mutations in EGFR in circulating tumor cells using SARMS assay and CTC-chip. The research investigates the effectiveness of these non-invasive methods in analyzing tumors and explores the role of the T790M mutation in resp

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Overview of the Nervous System Components and Functions

The nervous system is comprised of the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS acts as the command center, interpreting sensory information and coordinating responses. The PNS conveys information to and from the CNS through somatic and visceral sensory neurons,

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Understanding Mutations: Types, Causes, and Significance

Explore the world of gene mutations and chromosome mutations, including point mutations, frameshift mutations, and changes in chromosome structure. Learn about the significance of mutations, how they can be inherited or acquired, and their impact on genetic information. Uncover examples of neutral,

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Exploring Damage-Related Protein Turnover in Relation to Somatic Maintenance in the DEB Theory

Unraveling the intricacies of somatic maintenance, this study delves into the role of protein turnover in explaining inter-specific maintenance rate patterns within the Dynamic Energy Budget (DEB) framework. Empirical observations shed light on the metabolic processes involved in maintaining organis

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Mutations in Coenzyme Binding Sites and Related Diseases

Mutations in coenzyme binding sites can lead to diseases by impacting enzyme affinity and reaction rates. Defects in proteins like ornithine aminotransferase and cystathionine-synthase result in conditions such as gyrate atrophy of the choroid and retina, homocystinuria, and X-linked sideroblastic a

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Understanding Gene Pools, Allele Frequencies, and Mutations in Population Genetics

Dive into the significance of gene pools and allele frequencies, exploring how mutations drive the emergence of new alleles. Learn about factors impacting allele frequencies like mutations, environmental pressures, genetic drift, and gene flow. Discover the types of mutations and their effects on po

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Understanding Mutations and Their Effects on DNA

Learn about the structure of DNA, DNA replication, and various types of mutations such as substitution, deletion, and insertion. Explore how mutations occur, their effects at the molecular level, and how environmental factors can influence them. Discover the impact of mutations through examples of s

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Understanding Plant Tissue Culture and Regeneration Pathways

Plant tissue culture techniques such as Organogenesis and Somatic Embryogenesis play a crucial role in regenerating whole plants from meristem cells. The process involves the formation of organs directly from explants or callus structures and the production of adventitious organs like roots, shoots,

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Understanding Mutations and Natural Selection in Genomes

Explore how mutations impact survival and how genomes record these changes, distinguishing between functional and nonfunctional sequences. Learn about the effects of mutations on organism survival and the role of natural selection in shaping genetic variability.

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Understanding Mutations in Biology: Clicker Questions Explained

Explore a series of clicker questions related to mutations in biology, covering topics such as the definition of mutations, their effects, inheritance patterns, and the impact on amino acid sequences. Gain insights into how mutations occur, their consequences, and their role in genetic processes.

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Understanding Human Genetic Variation and Its Implications

These slides explore the connection between genetic variations and phenotypes, focusing on how the human genome varies between individuals, identifying associations with phenotypes/diseases, and the impact of sequencing technologies on reading the genome. The evolution of projects like HapMap and th

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Understanding Chromosomal and Gene Mutations in Genetics

Chromosomal and gene mutations play a crucial role in genetic variations. Mutations such as insertion, deletion, and substitution can lead to significant changes in DNA sequences, affecting gene expression and cellular functions. Additionally, chromosomal mutations like deletion, amplification, inve

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Understanding Genetic Mutation and Its Impact on Evolution

Genetic mutations are a natural process that introduces variations in DNA sequences, creating new alleles and genetic diversity within populations. These mutations can have both positive and negative effects on individuals, influencing survival and reproduction. By examining different types of mutat

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Understanding Bacterial Genetics: Phenotypic and Genotypic Variability

Phenotypic and genotypic variations in bacteria are crucial for their adaptation and survival. Phenotype reflects the physical expression influenced by both the genome and the environment, while genotype represents the hereditary constitution passed to offspring. Mutations are a primary source of ge

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Comprehensive Analysis of Somatic Mutations in eMERGE Datasets

This investigation delves into somatic mutations across normal tissues, revealing macroscopic clonal expansions. The study processed a large number of samples and identified candidate mutations, with characteristics and functional predictions detailed. Genes with the most somatic mutations are highl

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