OCTIVUS Randomized Clinical Trial: OCT-Guided vs IVUS-Guided PCI
The OCTIVUS Randomized Clinical Trial compared the clinical efficacy and safety of Optical Coherence Tomography (OCT)-guided and Intravascular Ultrasound (IVUS)-guided strategies in patients undergoing PCI for significant CAD. The study aimed to determine if OCT-guided PCI is noninferior to IVUS-gui
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Extracorporeal Life Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock
This study explores the use of extracorporeal life support (ECLS) in patients with acute myocardial infarction complicated by cardiogenic shock. The researchers investigate the impact of ECLS on mortality and various secondary endpoints such as renal failure, recurrent infarction, and need for revas
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Comparison of FFR-guided PCI vs Angiography-guided PCI in AMI with Multivessel Disease: FRAME-AMI Trial
In patients with acute myocardial infarction (AMI) and multivessel coronary artery disease, this study aims to compare fractional flow reserve (FFR)-guided PCI with angiography-guided PCI for non-infarct-related artery lesions. The hypothesis is that selective PCI guided by FFR is superior to routin
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Understanding Chronic Coronary Syndrome: Causes, Symptoms, and Management
Chronic coronary syndrome involves a dynamic process of atherosclerotic plaque accumulation and functional alterations in coronary circulation. It includes various clinical scenarios such as stable angina, asymptomatic ischemia, prior myocardial infarction, and more. The condition can be modified by
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Comparative Study on Health Effectiveness in Chronic Kidney Disease
Study focuses on the benefits of adding cardiac catheterization and revascularization to medical therapy in stable CKD patients with moderate ischemia. The ISCHEMIA-CKD trial compared invasive versus conservative treatment strategies, enrolling high-risk patients with various comorbidities. Results
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Prognostic Value of Post-PCI FFR and Intravascular Imaging in FAME 3 Trial
This study investigates the prognostic value of measuring post-PCI Fractional Flow Reserve (FFR) and intravascular imaging in patients with complex 3-vessel coronary artery disease (CAD), focusing on the impact on outcomes such as target vessel failure (TVF), including cardiac death, target vessel m
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Advancements in Hybrid Coronary Revascularization
Explore the evolution of hybrid coronary revascularization in cardiovascular care, guided by the 2011 ACC/AHA guidelines. This groundbreaking approach combines LIMA-to-LAD grafting with PCI for complex CAD cases, offering a promising alternative to traditional CABG or multivessel PCI. The integratio
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Understanding Coronary Revascularization: Anatomy vs. Physiology
This content discusses the prevalence of angina in women compared to men, the importance of stable angina in predicting outcomes, the need for better diagnostic methods for coronary angiography, and the differences in obstructive CAD by sex and ethnicity in stable angina cases. It highlights the cha
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Comparison of Revascularization Strategies in Multivessel Disease After STEMI
Primary PCI is the preferred method for STEMI patients, but treating multivessel coronary artery disease remains a challenge. The COMPLETE trial compared complete revascularization with culprit-only revascularization in patients with STEMI and multivessel disease. The trial included over 4,000 patie
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Exploring the Latest Research on Carotid Artery Disease Treatment
This comprehensive update discusses recent findings and ongoing studies related to carotid artery disease treatment options, particularly focusing on revascularization procedures in symptomatic and asymptomatic patients. Key trials like ECST-2, ACTRIS, EVA-3S, SPACE, ICSS, CREST, and more are highli
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