Oncology drug development - PowerPoint PPT Presentation


8th Next-Gen Immuno-Oncology Conference | 7th - 8th March 2024

Welcome to the 8th Annual MarketsandMarkets Next-Gen Immuno-Oncology Conference, a premier event dedicated to advancing the field of immuno-oncology. Join us on 07th - 8th March 2024 in London, UK, where leading experts, researchers, and industry professionals will gather to shape the future of canc

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Understanding and Managing Burnout in Oncology Care: A Path to Better Well-being and Quality Care

In the field of oncology care, the importance of effective management to reduce burnout among healthcare providers is highlighted. Stress, psychosocial risks, and burnout definitions are explored, emphasizing the impact on healthcare professionals' well-being and job satisfaction. Studies reveal hig

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Age-Friendly App: Managing Drug-Drug Interactions Between Prescriptions and OTC Analgesics

The Age-Friendly app addresses the crucial issue of drug-drug interactions between current prescriptions and over-the-counter analgesics in the geriatric population. With a significant percentage of OTC sales attributed to older adults, there is an increased risk of adverse drug events due to polyph

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The Role of Gemtuzumab 4.5 mg in Precision Oncology

\n\nGemtuzumab 4.5 mg is a monoclonal antibody that targets CD33 antigen, which is found on the surface of leukemia cells. In precision oncology, this drug has been used to treat patients with acute myeloid leukemia (AML) who are deemed appropriate for this therapy. It has been shown to increase sur

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Next-Gen Immuno-Oncology Conference |20th - 21st June 2024| USA

Our 7th Annual MarketsandMarkets Next Gen Immuno-Oncology Conference to be held on 20th - 21st June 2024, in Hilton Boston Logan Airport, One Drive, Boston, MA 02128, USA would address the challenges and future directions in IO research. \n\nRegister Now @ \/\/events.marketsandmarkets.com\/immuno-on

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Real-World Evidence (RWE) Oncology Market - Offline vs. Online Sales Growth

RWE Oncology Market by Component (Datasets [EHR, Claims, Cancer Registries], Consulting & Analytics Services), Application (Drug Development, Approval, Market Access, Post Market Surveillance), End User (Pharma, Payer, Provider) - Global Forecast to 2029

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Understanding Regulatory Requirements of Drugs and Pharmaceuticals

Drug regulation involves controlling drug use through international agreement authorities like the FDA, EMA, and PMDA. The FDA plays a crucial role in drug evaluation and research, biologic evaluation, devices, and food safety. There are various types of applications for drug approval, along with a

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Basics of Medical Terminology in Health Care Oncology

This module provides training on medical terminology basics for patient navigators in oncology. It covers defining terms using prefixes, root words, and suffixes, common oncology words, and available resources. Learn how to approach medical terminology effectively by understanding word roots and com

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Polymeric Controlled Drug Delivery Systems

Polymeric controlled drug delivery systems play a crucial role in regulating drug release through diffusion, solvent penetration, and chemical mechanisms. These systems include diffusion-controlled, solvent-controlled, and chemically-controlled devices, each operating based on specific principles. S

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Renal Pharmacology: Drug Excretion and Renal Clearance Questions

This comprehensive set of questions and answers covers topics related to drug excretion and renal pharmacology. It includes information on glomerular filtration, drug excretion mechanisms, dosage adjustments in renal impairment, factors influencing drug excretion, and the effects of long-term NSAID

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Understanding Estimands in Oncology Clinical Trials

The concept of estimands in oncology clinical trials plays a crucial role in defining treatment effects and analyzing overall survival outcomes. This framework aims to enhance transparency, align trial objectives, and strengthen interdisciplinary dialogues. Introduced by the ICH E9(R1) guideline in

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Understanding Nasopulmonary Drug Delivery System

Nasopulmonary drug delivery system, utilizing the nasal route for drug administration, offers advantages such as hepatic first-pass metabolism avoidance and rapid drug absorption. This system is beneficial for pharmacologically active compounds with poor stability in gastrointestinal fluids. While i

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Understanding Physicochemical Properties of Drugs

The physicochemical properties of drugs play a crucial role in their pharmacological effects. These properties include physical and chemical characteristics that influence interactions with biomolecules. Solubility, partition coefficient, and dissociation constant are key factors affecting drug beha

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Understanding Formulary Systems in Healthcare

A formulary is a dynamic list of medications curated by healthcare professionals to guide drug selection based on efficacy, safety, cost, and patient acceptability. It plays a vital role in promoting evidence-based and cost-effective drug therapy, improving communication between prescribers and phar

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Ways to Stay Drug Free: Lessons for Teens and Families

Understanding the reasons behind drug usage among teens, this lesson provides valuable resources and strategies to stay drug-free. It emphasizes the importance of making healthy decisions and offers alternatives to drug use. Additionally, it highlights the significance of saying no to drugs, provide

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Understanding the Hatch-Waxman Act: Promoting Affordable Generic Drugs

The Hatch-Waxman Act, also known as The Drug Price Competition and Patent Term Restoration Act, was enacted in 1984 to amend patent laws and the Federal Food, Drug, and Cosmetic Act. It aims to reduce costs associated with generic drug approval, allow early experimental use, compensate branded drug

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West Midlands Acute Oncology Directory of Services - Hospital Contact Information

This document lists contact information for various hospitals in the West Midlands area related to acute oncology services, including details of 24-hour advice lines, oncology nurses, consultants, and specific cancer service leads. Updates and changes to the information should be notified via email

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Understanding Biopharmaceutics: pH Partition Theory and Drug Absorption

Biopharmaceutics explores how drug properties and administration methods impact drug absorption. Factors affecting oral absorption include membrane physiology and drug partitioning based on pH levels. The pH partition theory, explained by Brodie et al., highlights the role of drug lipid solubility a

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Importance of In-Vitro Dissolution Testing in Drug Assessment

In drug development, in-vitro dissolution testing plays a crucial role in evaluating drug release from tablets when in-vivo bioavailability studies are limited. By ensuring drug release is close to 100% and uniform batch to batch, these tests help assess drug availability and effectiveness. Regulato

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Understanding Pharmacodynamics: Potency and Efficacy

Pharmacodynamics explores how drugs interact with receptors in the body, affecting the magnitude of drug effects based on concentration. Graded dose-response relationships, potency, and efficacy play key roles in determining drug efficiency. Potency reflects the amount of drug needed for a specific

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Understanding Drug Absorption, Excretion, and Bioavailability in Humans

Delve into the complex processes of drug absorption, excretion, and bioavailability in the human body. Learn about the various factors affecting drug absorption from the gastrointestinal tract, including biological, physiochemical, and pharmaceutical factors. Explore the mechanisms of drug transport

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Understanding Quantitative Aspects of Drug Action

Explore the quantitative aspects of drug action, including drug receptor binding, concentration binding curves, dose-response curves, and types of antagonism. Learn to relate drug concentration to receptor binding capacity and response produced. Discover how concentration binding curves and dose-res

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Review of DRE School and Drug Evaluation Techniques

Explore key topics such as the definition of drugs for DRE purposes, basic drug statistics, review of symptomatology, and vital signs assessment in the context of Drug Recognition Expert (DRE) training. Learn about CNS depressants, stimulants, hallucinogens, and analogs, as well as vital signs like

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Study on Juvenile Drug Crime Prevention in Taiwan: Insights from ACS Conference 2020

This presentation at the Asian Criminological Society Conference 2020 delves into the current situation, dilemmas, and responses regarding juvenile drug crime prevention in Taiwan. The presenter, Zeng Li-Wen, a PhD student at Central Police University in Taiwan, provides valuable insights based on t

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Understanding Drug Abuse: Definitions, Effects, and Stages

Drug abuse is a serious issue involving various substances like prescription drugs, alcohol, and illegal drugs. This includes terms and definitions, effects on the body and mind, stages of addiction, and withdrawal symptoms. Factors influencing drug action and reasons for drug use are also explored.

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Emerging Trends in Clinical Trial Designs for Oncology Drug Development

Master protocols, seamless trials, and adaptive designs are revolutionizing oncology drug development. These innovative approaches involve multiple substudies with different objectives, evaluating investigational drugs across disease subtypes. Basket trials and umbrella trials offer flexibility in s

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Understanding Drug Targets and Mechanisms of Action

Explore the intricate world of pharmacokinetics and pharmacodynamics, from drug absorption to their interaction with biological molecules. Learn about different drug targets, such as proteins and ions, and how drugs alter their biochemical and biophysical activities. Dive into molecular mechanisms o

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International Day Against Drug Abuse and Illicit Trafficking 2022 Initiatives and Awareness

The United Nations observes 26th June as the International Day Against Drug Abuse and Illicit Trafficking to combat substance abuse worldwide. Various initiatives like the National Drug Master Plan, Nasha Mukt Bharat Abhiyaan, and the National Action Plan for Drug Demand Reduction aim to raise aware

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Comprehensive Review of Drugs, Categories, and Drug Influence Evaluation

This mid-course review covers key aspects such as defining drugs, naming drug categories and subcategories, identifying drug categories for specific drugs, components of drug influence evaluation, and examinations conducted as part of the evaluation process. The content also includes identifying dru

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Evolution of Oncology Drug Development Strategies

Explore the shifting trends in oncology drug development, from understanding cancer mechanisms to new immuno-oncology approaches. Delve into the role of statisticians in researching cancer drugs and uncover the importance of early-phase trials in validating treatment mechanisms. Discover the need fo

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Patient Feedback Summary for Neuro-Oncology Services at Bristol Haematology Oncology Centre

Patient feedback for the Neuro-Oncology services at Bristol Haematology Oncology Centre reflects a consistently positive experience. Patients found the staff to be supportive, informative, attentive, caring, and empathetic. The professionalism, humanism, kindness, and generosity of the oncology team

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Advanced Moisture Renewal Mask for Oncology Spa Services

Bel Mondo Beauty introduces a breakthrough Moisture Renewal Mask made from bio cellulose, a fabric with incredible skin affinity and efficient ingredient transfer. This professional series mask targets oncology spa services, developed in collaboration with Oncology Spa Solutions to care for clients

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Impact of Socioeconomic Conditions on Drug Use Disorders: Insights from World Drug Report 2020

The World Drug Report 2020 highlights the strong correlation between socioeconomic factors and drug use disorders. Studies reveal that communities facing poverty, violence, and social inequality are at a higher risk of drug overdoses and addiction. Factors like income inequality, lack of social capi

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Optimal Basket Designs for Efficacy Screening with Cherry-Picking

Efficacy screening in oncology trials involves evaluating multiple tumor types simultaneously to enhance drug development efficiency. Basket trials minimize missed opportunities but risk cherry-picking for positive results. Statistical methods, like multiplicity control and Bayesian information borr

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Understanding Targeted Clinical Investigation in Pharmacovigilance

Targeted clinical investigation plays a crucial role in pharmacovigilance by further evaluating significant risks identified in pre-approval clinical trials. This involves conducting pharmacokinetic and pharmacodynamic studies, genetic testing, interaction studies, and large simplified trials to ass

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Advances in Ophthalmic Drug Delivery Systems

This content explores various advanced ophthalmic drug delivery systems including erodible ophthalmic inserts, soluble ocular drug inserts, new ophthalmic drug delivery systems, and bioadhesive ophthalmic drug inserts. These innovative systems aim to provide accurate dosing, prolonged drug release,

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State Responsible Inmates with Marijuana Convictions Research Report

Research conducted by VADOC indicates a total of 570 state responsible inmates incarcerated for marijuana-related offenses as of August 31, 2021. Among them, 229 inmates had non-drug-related Most Serious Offenses, 331 were convicted for Drug Sales MSO, and 10 were convicted for Drug Possession MSO.

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Innovative Online Learning for Drug Court Professionals

Center for Court Innovation has introduced a new National Drug Court Online Learning System aimed at assisting drug court professionals. This system offers free access to web-based training, expert video lessons, virtual site visits to drug treatment courts, practitioner interviews, and a resource l

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Understanding Drug Testing Policies in the Workplace

The Drug-Free Workplace Act of 1988 mandates federal grant recipients to implement zero-tolerance drug policies to maintain a drug-free environment. Employers must establish clear policies, conduct awareness programs, offer counseling and rehabilitation services, and impose penalties for violations.

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Phase II Trial Design in Oncology Drug Development by Wendy R. Parulekar, MD, FRCP

This presentation covers the pivotal role of Phase II trials in oncology drug development, emphasizing the importance of preliminary clinical efficacy screening, adverse event profiling, mechanism of action understanding, and target population definition. It discusses various Phase II trial designs,

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