The EBMT Activity Survey on Hematopoietic Cell Transplantation (HCT) in 2021 gathered data from 694 teams across 52 countries, totaling 43,109 patients and 47,412 transplants. The survey provides insights into patient numbers, donor types, main indications, and lymphoid neoplasia trends in allogenei

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Electroconvulsive Therapy (ECT), also known as electroshock, is a psychiatric treatment that induces seizures in anesthetized patients for therapeutic purposes. ECT has a controversial history but is well-established in the medical field. Introduced in 1938, ECT has replaced older treatments like in

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The updated guidelines for penile cancer management emphasize the importance of a specialist penile cancer team for all operations, the necessity of regular MDT meetings, and the terminology change to classify cases under Penile Intra-epithelial Neoplasia. The clinical pathways stress referrals to d

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Comprehensive updates on European training requirements for rare diseases, rare adult solid cancers, and neuroendocrine neoplasia medicine. Initiatives include syllabi, competencies, and collaborations with international networks for advancements in the field.

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Galactopoiesis is the process of maintaining lactation in animals, involving hormones like prolactin, GH, cortisol, PTH, insulin, and oxytocin. This process also includes the role of progesterone, estrogen, and other hormones in milk production and release. Milk ejection, facilitated by oxytocin, in

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Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor that requires specialized management. This comprehensive guide covers the clinical presentation, diagnosis, genetic aspects, and detailed management strategies for MTC, including surgical options, follow-up evaluation, and systemic the

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Research presented at the ENETS 2020 virtual meeting discussed the generation of organoids from lung, intestinal, and pancreatic neuroendocrine neoplasms (NENs) to study normal neuroendocrine cells and their transformation to NENs. The success rate in generating organoids was higher for lung NENs co

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Delve into the complex world of neuroendocrine tumors (NETs) through a detailed presentation prepared by Dr. Thomas O'Dorisio from the University of Iowa. Explore case reports, therapeutic interventions, and the challenges associated with managing these tumors. Gain valuable insights into the functi

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Neoplasia encompasses abnormal tissue growth that can be benign or malignant. This article explores neoplastic terms, tumor classifications, cancer staging, and genetic factors in cancer development. Gain insights into the characteristics of benign tumors, the biology of cancer including carcinogene

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Neoplasia, or new growth, is characterized by uncoordinated growth exceeding that of normal tissues, persistent growth independent of stimuli, loss of responsiveness to growth controls, and local expansion regardless of host environment. Tumors are classified into benign and malignant categories in

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A 3-year-old girl presented with persistent fever, leading to the discovery of a cardiac mass diagnosed as histiocytic neoplasia through imaging and biopsy. Primary cardiac tumors are rare in children, with benign tumors being more common. Histiocytic sarcomas are malignant neoplasms with characteri

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Understanding the classification of tumors is crucial in the field of pathology. This detailed overview covers the definitions of neoplasia and tumors, the differentiation between benign and malignant tumors, nomenclature, and characteristics of various tumor types. It discusses the behaviors of ben

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Phaeochromocytoma, a neuroendocrine tumor of the adrenal medulla, presents unique challenges in anesthesia due to excessive catecholamine secretion. From clinical presentation to familial associations, this condition requires careful diagnosis and management to avoid complications during surgery. Un

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Peptide Receptor Radionuclide Therapy (PRRNT) is a targeted approach using radiopharmaceuticals to deliver radiation to neuroendocrine tumors expressing specific receptors. This therapy, involving 90Y-DOTATOC or 177Lu-DOTATATE, has shown promising results in treating NETs with minimal side effects.

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This presentation delves into the complexities of Opioid Use Disorder (OUD), discussing its impact on the neuroendocrine system, treatment options, including Medications for Opioid Use Disorder (MOUD), and special populations. The objective is to connect endogenous mechanisms to clinical observation

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Neoplasia refers to abnormal tissue growth surpassing normal growth, persisting excessively even after the initial stimulus. Odontogenic tumors are classified by the WHO in 1992 into benign and malignant categories, with various subtypes described. Ameloblastoma is a true neoplasm of enamel organ ti

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Explore the emerging role of non-18F-FDG tracers in PET/MR imaging for oncology, focusing on their use in detecting neuroendocrine tumors and prostate cancer. Learn about the potential benefits of these tracers and the challenges they address in tumor localization and staging.

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This study presents an analysis of thymic neuroendocrine tumors (TNET) focusing on demographics, treatment, and survival outcomes. Conducted as a retrospective cohort study using the NCDB data from 2004 to 2015, the study aimed to examine the characteristics of TNET in terms of demographics, clinica

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A multi-cohort phase 2 study presented at ESMO 2020 evaluated the combination of durvalumab and tremelimumab in patients with advanced neuroendocrine neoplasms. The DUNE trial assessed the efficacy of this immunotherapy approach in various neuroendocrine tumor types, emphasizing the potential benefi

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Explore the comprehensive overview of thyroid disorders, including hyperthyroidism, hypothyroidism, thyroid cancer, and more. Delve into learning objectives such as Grave's Disease, Thyroiditis, and Multiple Endocrine Neoplasia. This educational content covers essential information for understanding

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Pancreatic neuroendocrine tumors (panNETs) can be classified as functioning or non-functioning, with functioning tumors producing active hormones such as insulin, glucagon, gastrin, or VIP. Symptomatic control is crucial for managing these tumors, with diagnoses based on clinical syndromes and hormo

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Update from the ESMO 2019 meeting in Barcelona focusing on neuroendocrine tumors (NETs). Highlighting challenges in diagnosis and treatment, including limited knowledge and late diagnosis. Discusses different types of NETs, prevalence, approved therapeutic options, and key trials presented at the co

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The body's functions are coordinated by various chemical messenger systems, including neurotransmitters, endocrine hormones, neuroendocrine hormones, paracrines, autocrines, and cytokines. Endocrine hormones travel through the circulatory system, binding to receptors in cells to regulate metabolism,

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