Metabolic bone disease
Understand the metabolism of calcium and phosphorus, common disturbances, and nutrient requirements in preterm infants. Learn why metabolic bone disease is important and its long-term effects on bone health.
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Understanding Steatotic Liver Disease: Importance, Epidemiology, and Pathology
Steatotic liver disease, including metabolic dysfunction associated steatohepatitis (MASLD) and metabolic associated alcoholic liver disease (MALD), is a common cause of liver test abnormalities in the United States. Risk factors such as obesity and metabolic syndrome can lead to advanced fibrosis a
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Electrolyte and Metabolic Disturbances in the Critically Ill
Dr. Srilekha Ammapalli discusses the cations (sodium, potassium, calcium, magnesium) and anions (chloride, bicarbonate, phosphate, lactate) involved in electrolyte and metabolic disturbances in critically ill patients. The physiology, causes of abnormalities, diagnosis, evaluation, and management of
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Diabetic Ketoacidosis: Understanding Metabolic Acidosis in Diabetes
Explore a case study on diabetic ketoacidosis to understand the basis of metabolic acidosis in type 1 diabetes mellitus, differentiate between type 1 and type 2 diabetes, predict blood buffer equilibrium changes, apply Winter's formula, correlate clinical data with biochemical tests, explain insulin
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Understanding the Role of Phosphatase Enzymes in Metabolic Reactions
Phosphatase enzymes play a crucial role in various metabolic processes by releasing phosphate groups, increasing their availability for energy synthesis and cell structure formation. Acid phosphatases, with an optimum pH below 7.0, can be extracted from plant tissues like germinating mung beans. A p
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Overview of Glucose Metabolic Pathways in Clinical Chemistry
Explore the major metabolic pathways of glucose, including glycogenolysis, gluconeogenesis, glycolysis, and more. Understand the production, utilization, catabolic, and anabolic cycles of glucose in cellular metabolism. Learn about key concepts such as hexose interconversion, HMP/PPP, Krebs cycle, a
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Regulation of Energy Homeostasis by AMPK System and Its Modulation Factors
The AMPK system plays a crucial role in regulating energy homeostasis by sensing the cellular AMP:ATP ratio and responding to metabolic stresses that affect ATP production or consumption. AMPK is activated by factors such as hypoxia, glucose deprivation, and metabolic inhibitors, as well as by compo
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Techniques for Investigating Plant Metabolic Pathways and Biogenetic Studies
This content explores various techniques used in pharmacognosy and phytochemistry to investigate the metabolic pathways in plants and study the formation of primary and secondary metabolites. Methods such as utilizing radioactive isotopes, tracer techniques, isolated organs/tissues, grafting, and mu
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Understanding Acid-Base Balance in Health and Disease
Many critical illnesses can disrupt acid-base balance, indicating underlying diseases or organ damage. Interpretation of disturbances requires analyzing arterial blood gases, plasma electrolytes, and compensatory mechanisms. Acid-base disorders are classified into respiratory acidosis, respiratory a
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Managing Nutritional and Metabolic Diseases in Zoo and Wild Animals
The prevention, control, and treatment of nutritional and metabolic diseases in zoo and wild animals are essential for maintaining their health. These diseases, such as rickets, osteoporosis, osteomalacia, and fibrous osteodystrophy, can result from imbalances in dietary nutrients and metabolic dera
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Career and College Promise in Duplin County: Pathways to Success
Elizabeth Turner Howard Career and College Promise in Duplin County offers College Transfer Pathways and Career & Technical Education Pathways with 22 pathways available. High school students can pursue various pathways based on different requirements such as GPA, college readiness scores, and recom
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Abomasal Displacement in Veterinary Medicine
Abomasal displacement refers to the movement of the abomasum, a wandering organ in cattle due to loose attachments. This condition can lead to left or right displacement, as well as torsion or volvulus. Various factors such as feeding high concentrate rations, metabolic alkalosis, and other metaboli
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Understanding Metabolic Control Mechanisms in Cellular Regulation
Metabolic control mechanisms play a crucial role in maintaining homeostasis within cells by regulating metabolic pathways. This involves finely adjusting the output of pathways in response to external signals, ensuring the proper flux of metabolites to meet cellular needs. Pacemaker enzymes, such as
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Understanding Thyroid Hormones: Biosynthesis, Functions, and Clinical Implications
This educational material delves into the types and biosynthesis of thyroid hormones, the physiological actions of thyroid hormones, regulation levels, thyroid function tests, goiter, and the distinction between hypo- and hyperthyroidism. It covers the role of thyroid hormones in thermogenesis, meta
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Understanding Cutaneous Circulation and Blood Supply in Different Body Regions
Cutaneous circulation plays a vital role in supplying blood to the skin, with variations in apical and non-apical regions of the body. The blood flow is regulated by neural, thermal, and metabolic factors, and controlled by sympathetic fibers. Sympathetic vasoconstriction and vasodilation affect the
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Importance of Nutrition in Patient Healing and Recovery
Gain insight into the critical role of nutrition in aiding patients in their recovery from injuries and enhancing their physical well-being post-injury. Explore the phases of injury, the physiological and metabolic impacts of each phase, and the corresponding nutritional support strategies. Delve in
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Diagnosis Criteria for Perinatal Asphyxia
Perinatal asphyxia refers to the interruption of oxygen supply to the fetus or newborn, leading to metabolic consequences and potential multiorgan dysfunction and long-term neurological issues. The American Academy of Pediatrics (AAP) and the American College of Obstetrics and Gynecology (ACOG) have
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Overview of Glycine Metabolism and Its Importance in the Body
Glycine, the simplest amino acid, plays a crucial role in various metabolic pathways in the body. It can be converted to important compounds like pyruvic acid, lactic acid, and creates the one-carbon pool. Glycine is essential for heme synthesis, glutathione formation, purine synthesis, and more. In
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Understanding Inborn Errors of Metabolism and Metabolic Disorders
Inborn Errors of Metabolism (IEM) are genetic disorders that disrupt metabolic pathways, leading to substrate accumulation or product deficiency. These disorders can be classified based on toxic accumulation, protein metabolism, carbohydrate intolerance, lysosomal storage issues, energy production d
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Understanding Metabolic Pathways in Organisms
Exploring the intricate world of metabolism, this topic delves into the chemical reactions within organisms. From anabolic to catabolic pathways, enzymes play a crucial role in controlling these processes. Learn about reversible and irreversible reactions, alternative pathways, and the vital role of
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Methods of Detection in Tracer Technique for Biogenetic Studies
Explore the methods utilized in tracer techniques for investigating biogenetic pathways in plants. Learn about competitive feeding, precursor-product sequence method, sequential analysis, and isotope incorporation. These methods involve labeling experiments to trace metabolic pathways and understand
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Understanding Basal Metabolic Rate and Energy Balance
Energy is essential for various bodily functions, with Basal Metabolic Rate (BMR) representing the energy needed to sustain internal organ activity and body temperature. Kilocalories from food play a crucial role, and maintaining an energy balance is key for overall health. Factors like exercise, ho
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Insights into Hibernation in Animals: Functions and Varieties
Hibernation is a fascinating biological phenomenon observed in various animals, enabling them to survive harsh conditions by conserving energy. This state of inactivity and metabolic depression is crucial for species like bears, pygmy possums, and bats during winter months. Animals hibernate to cope
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Utilizing a Global Model for Analyzing Reaction Pathways in Plasma Systems
This research focuses on using a kinetic global model framework to identify relevant reactions in chemically complex plasma systems. The framework, KGMf, enables the investigation of macroscopic plasma characteristics by analyzing reaction pathways, sensitivity to reaction rate errors, and dominant
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Multidimensional Optimality of Microbial Metabolism
Exploring the multidimensional optimality of microbial metabolism through metabolic network analysis, C-based flux analysis, and stoichiometric reaction modeling. The concept of Pareto optimal solutions in multi-objective optimization problems is discussed in the context of microbial metabolic pathw
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Understanding Metabolic Rate in Biology: Measurement and Importance
Metabolic rate, the energy consumed by an organism in a specific time period, can be measured through heat energy, oxygen consumption, and carbon dioxide release. Various tools like calorimeters and respirometers are used for this purpose. The delivery of oxygen through efficient transport systems i
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Metabolic and Mechanical Cost of Sedentary and Physical Activities in Obese Children and Adolescents
A study by Stefano Lazzer, Grace O. Malley, and Michel Vermorel explores the metabolic and mechanical costs of sedentary and physical activities in obese children and adolescents. The research delves into the main components of daily energy expenditure, the contribution of organs and tissues to body
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Dr. Zoidis Evangelos: Endocrinology & Metabolic Syndrome Expert at Agricultural University of Athens
Dr. Zoidis Evangelos is a distinguished professional in the field of endocrinology and metabolic syndrome, currently serving as a Lecturer at the Agricultural University of Athens. With a background in biochemistry and extensive research experience, his work focuses on nutritional physiology, molecu
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Optimizing Brain Health through Metabolic Tune-Up: A Case-Based Review
Explore the case of a 48-year-old RN facing various health challenges like depression, anxiety, obesity, diabetes, and more. Learn about core metabolic imbalances impacting brain health, personalized lifestyle medicine strategies, and the importance of addressing root causes for a balanced metabolic
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Understanding Metabolic Rate Measurement Techniques
Metabolic rate, the amount of energy used by the body over time, can be measured in different ways using respirometers and calorimeters. Respirometers measure oxygen uptake, while calorimeters calculate metabolic rate based on heat generated by the organism. Understanding these techniques is essenti
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Career and College Promise Program Details in Duplin County
Explore the Career and College Promise (CCP) program in Duplin County at James Sprunt Community College, offering College Transfer Pathways (CTP) and Career & Technical Education Pathways (CTE). The program includes various pathways, eligibility requirements for high school students, and opportuniti
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Understanding Metabolic Pathways and Regulatory Mechanisms
Metabolic pathways are a series of enzymatic reactions interconnected to form a flow of substrates and products. Irreversible steps, known as committed steps, determine pathway direction. Regulation, through positive or negative feedback, controls enzyme activity. Branched pathways share common inte
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Launch Years Initiative: Transforming Math Pathways for Student Success
Launch Years Initiative (2022-2025) aims to support the scaling of math pathways aligned with student goals from high school to the workplace. Led by Dana Center at The University of Austin, the initiative involves 22 states and national education organizations to expand math pathways, improve align
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Understanding the Physiology of Basal Ganglia and Regulatory Mechanisms
This lecture covers the physiology of basal ganglia, including the different nuclei, pathways, and neurotransmitters involved. It explains the functions of caudate and putamen circuits, integration of direct and indirect pathways, and diagnosis of basal ganglia disorders. The connections and basic c
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Understanding Metabolic Interaction in Society
In a capitalist society, metabolic interactions and exchanges are influenced by one's income and occupation quality. This separation between human existence and nature is emphasized in the relation between wage labor and capital. Marx's writings highlight how labor is essential for the metabolic int
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Economic Analysis of Alternative Transition Pathways in Fuel Cycle
This study explores economic considerations in fuel cycle transition by analyzing alternative pathways to improve efficiency and reduce costs. Strategic buildout and leveraging of low-enriched uranium for fast reactors are key strategies to enhance the economics of transition pathways. The research
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Creating a Model Organism Database: The Importance and Process
In the realm of bioinformatics, the creation of Model Organism Databases (MODs) plays a crucial role in advancing genomic research and understanding the complexities of various organisms. MODs facilitate pathway analyses, omics data analysis, and the development of metabolic models, serving as valua
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Pathway Analysis in Systems Biology
This article delves into the realm of pathway analysis in systems biology, focusing on methods such as embedding new pathways, enumeration of elementary flux modes, flux variations in metabolic networks, and identification of profitable networks. It explores strategies for optimizing metabolic pathw
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Understanding Genetic Interaction and Epistasis in Biosynthetic Pathways
Genetic interaction and epistasis play crucial roles in determining phenotypic traits through the intricate network of genes, enzymes, and metabolic pathways. This concept is illustrated through a detailed explanation of how mutations in specific genes can affect the production of metabolites and ul
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Cardio-metabolic Abnormalities Among Normal Weight Individuals: A Cross-sectional Analysis of Race/Ethnicity in the U.S.
Overweight and obesity are known cardio-metabolic risk factors, but this study delves into abnormalities among normal-weight individuals. The research compares data from MESA and MASALA studies, including diverse race/ethnicity groups like White, African American, Hispanic American, Chinese American
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