Understand the metabolism of calcium and phosphorus, common disturbances, and nutrient requirements in preterm infants. Learn why metabolic bone disease is important and its long-term effects on bone health.

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The evidence-based science and clinical management of Cardiovascular-Kidney-Metabolic Syndrome (CKM) in this comprehensive slide set. Learn about the pathophysiological interactions, multi-organ dysfunction, and adverse cardiovascular outcomes associated with CKM.

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Steatotic liver disease, including metabolic dysfunction associated steatohepatitis (MASLD) and metabolic associated alcoholic liver disease (MALD), is a common cause of liver test abnormalities in the United States. Risk factors such as obesity and metabolic syndrome can lead to advanced fibrosis a

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Dr. Srilekha Ammapalli discusses the cations (sodium, potassium, calcium, magnesium) and anions (chloride, bicarbonate, phosphate, lactate) involved in electrolyte and metabolic disturbances in critically ill patients. The physiology, causes of abnormalities, diagnosis, evaluation, and management of

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Shock is a critical condition caused by an imbalance between cellular oxygen supply and demand, leading to organ dysfunction. Compensatory responses include increased heart rate, vasoconstriction, and hormonal adjustments. Recognizable features of shock include tachycardia, hypotension, cool clammy

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Explore a case study on diabetic ketoacidosis to understand the basis of metabolic acidosis in type 1 diabetes mellitus, differentiate between type 1 and type 2 diabetes, predict blood buffer equilibrium changes, apply Winter's formula, correlate clinical data with biochemical tests, explain insulin

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Phosphatase enzymes play a crucial role in various metabolic processes by releasing phosphate groups, increasing their availability for energy synthesis and cell structure formation. Acid phosphatases, with an optimum pH below 7.0, can be extracted from plant tissues like germinating mung beans. A p

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Explore the major metabolic pathways of glucose, including glycogenolysis, gluconeogenesis, glycolysis, and more. Understand the production, utilization, catabolic, and anabolic cycles of glucose in cellular metabolism. Learn about key concepts such as hexose interconversion, HMP/PPP, Krebs cycle, a

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The AMPK system plays a crucial role in regulating energy homeostasis by sensing the cellular AMP:ATP ratio and responding to metabolic stresses that affect ATP production or consumption. AMPK is activated by factors such as hypoxia, glucose deprivation, and metabolic inhibitors, as well as by compo

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This content explores various techniques used in pharmacognosy and phytochemistry to investigate the metabolic pathways in plants and study the formation of primary and secondary metabolites. Methods such as utilizing radioactive isotopes, tracer techniques, isolated organs/tissues, grafting, and mu

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Posterior Tibialis Tendon Dysfunction, also known as Adult Acquired Flat Foot Deformity (PTTD), is a condition that affects the tibialis posterior tendon, leading to reduced arch support. Common causes include obesity, trauma, age, and existing health conditions. Symptoms may include ankle pain, swe

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Many critical illnesses can disrupt acid-base balance, indicating underlying diseases or organ damage. Interpretation of disturbances requires analyzing arterial blood gases, plasma electrolytes, and compensatory mechanisms. Acid-base disorders are classified into respiratory acidosis, respiratory a

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The prevention, control, and treatment of nutritional and metabolic diseases in zoo and wild animals are essential for maintaining their health. These diseases, such as rickets, osteoporosis, osteomalacia, and fibrous osteodystrophy, can result from imbalances in dietary nutrients and metabolic dera

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Metabolic control mechanisms play a crucial role in maintaining homeostasis within cells by regulating metabolic pathways. This involves finely adjusting the output of pathways in response to external signals, ensuring the proper flux of metabolites to meet cellular needs. Pacemaker enzymes, such as

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Sexual dysfunction encompasses a range of issues that can affect individuals, with causes including psychological, neurological, hormonal, and relationship-related factors. Evaluating sexual problems involves considering duration, context, and frequency. Psychological causes, such as anxiety and str

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Discover the intricate anatomy of the spine, learn about the prevalence and causes of lower back pain, delve into the symptoms and diagnosis of sacroiliac joint dysfunction, and explore treatment options to manage this condition effectively.

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Perinatal asphyxia refers to the interruption of oxygen supply to the fetus or newborn, leading to metabolic consequences and potential multiorgan dysfunction and long-term neurological issues. The American Academy of Pediatrics (AAP) and the American College of Obstetrics and Gynecology (ACOG) have

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Movement dysfunction in sports medicine can stem from various factors such as structural instability, loss of range of motion, functional rigidity, poor balance, and more. Clinical movement analysis plays a vital role in identifying muscle imbalances and guiding exercise interventions to enhance ath

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Executive Functioning is a key aspect of cognitive function, encompassing various abilities such as planning, self-awareness, and emotion regulation. Executive Dysfunction, often resulting from frontal lobe injuries, can lead to difficulties in decision-making, social interactions, and learning. Thi

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Metabolic rate, the energy consumed by an organism in a specific time period, can be measured through heat energy, oxygen consumption, and carbon dioxide release. Various tools like calorimeters and respirometers are used for this purpose. The delivery of oxygen through efficient transport systems i

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A study by Stefano Lazzer, Grace O. Malley, and Michel Vermorel explores the metabolic and mechanical costs of sedentary and physical activities in obese children and adolescents. The research delves into the main components of daily energy expenditure, the contribution of organs and tissues to body

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An intriguing case study presents a young male with weakness and coma in the ICU following pneumonia and sepsis. Nerve conduction results indicated critical illness myopathy and polyneuropathy, along with cardiac abnormalities. Reduced muscle excitability was attributed to a sodium channelopathy. Th

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This consensus statement by the American Head and Neck Society Endocrine Surgery Section highlights the importance of recognizing immediate vocal fold paralysis (VFP) and partial neural dysfunction (PND) following thyroid and parathyroid surgery. The report emphasizes the need for early identificati

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Dr. Zoidis Evangelos is a distinguished professional in the field of endocrinology and metabolic syndrome, currently serving as a Lecturer at the Agricultural University of Athens. With a background in biochemistry and extensive research experience, his work focuses on nutritional physiology, molecu

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Understanding cognitive dysfunction in cancer patients is crucial for improving quality of life and medical outcomes. This article explores the background, causes, screening, diagnosis, and treatment options for cancer-related cognitive impairment, emphasizing the historical perspective, prevalence,

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Explore the case of a 48-year-old RN facing various health challenges like depression, anxiety, obesity, diabetes, and more. Learn about core metabolic imbalances impacting brain health, personalized lifestyle medicine strategies, and the importance of addressing root causes for a balanced metabolic

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Metabolic rate, the amount of energy used by the body over time, can be measured in different ways using respirometers and calorimeters. Respirometers measure oxygen uptake, while calorimeters calculate metabolic rate based on heat generated by the organism. Understanding these techniques is essenti

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In a capitalist society, metabolic interactions and exchanges are influenced by one's income and occupation quality. This separation between human existence and nature is emphasized in the relation between wage labor and capital. Marx's writings highlight how labor is essential for the metabolic int

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Discover how PDE-5 inhibitors go beyond treating erectile dysfunction, with approved and emerging compounds, alternative dose regimens, concentration sites, and potential targets like cardiovascular diseases and the central nervous system.

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The liver carries out essential metabolic, excretory, protective, synthetic, and storage functions in the body. Liver function tests play a crucial role in screening for liver dysfunction, recognizing patterns of liver disease, assessing patient prognosis, monitoring disease progression, and evaluat

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This guidance provides detailed information on COVID-19 and liver disease, covering topics such as COVID-19 overview, liver test abnormalities, co-morbidities, viral hepatitis B and C, metabolic dysfunction, autoimmune hepatitis, clinical care aspects, complications management, screening for HCC, an

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Radioactive iodine (RAI) is commonly used in treating differentiated thyroid cancer but can lead to salivary and lacrimal dysfunction. This joint clinical consensus statement by the American Head and Neck Society Endocrine Surgery and Salivary Gland Sections highlights the importance of understandin

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The thyroid gland, a vital part of the endocrine system, produces hormones that regulate metabolic processes, energy expenditure, and tissue growth. Dysfunction of the thyroid can lead to various disorders affecting overall health. Learn about the functions of thyroid hormones, diagnostic tests, and

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This research explores mapping the MMPI-2-RF substantive scales onto internalizing, externalizing, and thought dysfunction dimensions in mental health assessment. The study emphasizes the importance of validating assessments for accurate clinical pictures and effective treatment planning. It delves

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Pelvic floor dysfunction and prolapse are common issues affecting women, impacting their physical and emotional well-being. Surgical treatment may be necessary for symptomatic cases, but a thorough evaluation of symptoms, obstetric history, and other factors is crucial. Addressing precipitating fact

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Cardiorenal Syndrome is a condition where dysfunction in one organ, whether acute or chronic, can lead to dysfunction in the other. This complex relationship involves intricate communication pathways between the heart and kidneys, impacting hemodynamic stability, organ perfusion, and neurohormonal i

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The research explores the association between taste perception and the duration of COVID infection in long-COVID and COVID-reinfection cases. Reduced salivary gustin levels correlated with lower taste scores in long-COVID patients. The study also found an increase in the bitter taste receptor gene e

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Primary ovarian insufficiency, also known as hypergonadotropic amenorrhea, is a condition characterized by ovarian dysfunction in women under 40. It involves oligo/amenorrhea, elevated FSH levels, and impacts fertility and overall health. The pathophysiology includes follicle depletion and dysfuncti

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Voiding disorders in children, also known as bladder dysfunction, are a common issue affecting up to 40% of pediatric urology clinic visits. These disorders can indicate underlying pathophysiology requiring treatment to prevent renal or urologic damage. The development of urinary control by age 5 is

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Overweight and obesity are known cardio-metabolic risk factors, but this study delves into abnormalities among normal-weight individuals. The research compares data from MESA and MASALA studies, including diverse race/ethnicity groups like White, African American, Hispanic American, Chinese American

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