Immune deficiencies can be classified into primary hereditary disorders based on clinical presentations, including cell-mediated, antibody-mediated, non-specific, and complement activation deficiencies. Major clinical manifestations of immune disorders range from B-cell deficiencies to phagocytic ce

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Immune Thrombocytopenia (ITP) is a rare autoimmune disease where the immune system wrongly attacks platelets, leading to low platelet count. It can affect individuals of all ages, with symptoms appearing post-virus, vaccination, or certain medications. ITP can result in fatigue, bruising, and bleedi

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Chronic myeloid leukemia (CML), or chronic myelogenous leukemia, is a slow-growing form of cancer that affects the bone marrow and blood. Like acute myeloid leukemia, CML originates in the myeloid cells. When functioning properly, myeloid cells produce mature red blood cells, platelets and non-lymph

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Explore the fundamentals of electricity and circuits, including circuit components, cells, batteries, types of cells, primary vs. secondary cells, dry vs. wet cells, and ratings. Learn about the relevance of this knowledge in engineering and certifications like NABCEP PV Associate. Discover the work

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Dive into the world of immune system glossary terms with definitions and visual aids. Explore key concepts such as immune cell activation, adaptive immune response, antibodies, antigens, and more. Understand the complex processes within the immune system through informative images and concise explan

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The immune system acts as a defense mechanism against pathogens and infections, comprising various organs, such as the bone marrow, thymus, spleen, white blood cells, antibodies, complement system, and the lymphatic system. It works to recognize and destroy harmful microbes, maintaining the body's h

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Phage DNA can be introduced into bacterial cells through two methods: transfection and in vitro packaging. Transfection involves mixing purified phage DNA with competent E. coli cells, inducing DNA uptake via heat shock. In vitro packaging utilizes proteins coded by the phage genome, which can be pr

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Antigens are substances that stimulate the production of antibodies in the body, exhibiting specificity in immune reactions. They interact with immune response products like antibodies, BCRs, and TCRs. Immunogens induce detectable immune responses, leading to antibody production or T cell activation

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Understanding how parasites evade the immune system of their hosts is crucial in the field of immunoparasitology. Parasites have developed various strategies such as anatomical seclusion, antigenic variation, and intracellular living to avoid host immune responses. Examples include Plasmodium within

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Your blood, consisting of red blood cells, white blood cells, platelets, and plasma, plays a crucial role in transporting substances like oxygen, nutrients, and waste products throughout your body. Red blood cells are specialized for oxygen transport due to their unique adaptations, while white bloo

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Cytokines play a crucial role in immune response activation and regulation. They are secreted by various cell types like lymphocytes, monocytes, and macrophages, exerting diverse biological functions, including immune system development, inflammatory response induction, and hematopoiesis regulation.

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Autoimmunity refers to the immune system's failure to recognize its own cells, leading to attacks on self-tissues. Autoimmune disorders encompass over 80 chronic illnesses where the immune system mistakenly targets organs. These disorders are poorly understood and recognized, impacting various organ

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Autoimmunity is a condition where the body's immune cells mistakenly attack its own tissues, leading to damage. Immunological tolerance helps prevent this by mechanisms like central and peripheral tolerance. Central tolerance involves deleting self-reactive immune cells during maturation in key orga

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The immune system maintains a balance through tolerance mechanisms to prevent autoimmunity. Central and peripheral tolerance play crucial roles in immune unresponsiveness to self-antigens. Failure in immune regulation can lead to autoimmune diseases like diabetes and lupus. Vaccination, discovered b

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Stem cells are undifferentiated cells with the unique ability to develop into various specialized cell types, making them valuable for medical applications. Dr. J. Gowri explores the classification, features, and properties of stem cells, shedding light on their self-renewal and potency. These cells

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Stem cells are unique cells that have the potential to develop into various types of cells in the body. They play a crucial role in renewing and repairing tissues, offering hope for treating various medical conditions. While adult stem cells can differentiate into limited cell types, embryonic stem

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This detailed histological study covers the structure and function of the thyroid and parathyroid glands. It includes information on the stroma, parenchyma, follicular cells, parafollicular cells, and the microscopic structure of the parathyroid gland. The article also delves into the functions of v

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Parasitic infections pose complex challenges to the immune system due to the diverse nature of parasites, including protozoans and helminths. Protozoan parasites move between arthropod vectors and mammalian hosts, requiring both humoral and cell-mediated immune responses. Meanwhile, helminths, as mu

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Explore the intricate details of white blood cells (WBCs), their types, functions, formation, and crucial role in defending the body against infections. Delve into the immune system, comprising barriers, cells, tissues, and organs that combat invaders, with a focus on innate and adaptive immunity. L

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Observing well-defined cells with clear presence of cell walls would help conclude that the cells are plant cells, distinguishable from animal cells by the absence of cell walls. The detection of nuclei within each cell is a common characteristic observed in both plant and animal cells.

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Explore the intricate workings of the immune system, from its component parts and defense mechanisms to the significance of homeostasis maintenance. Discover how non-specific and specific immune responses, phagocytosis, neutrophils, natural killer cells, and interferons play vital roles in protectin

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Meiosis is a crucial process in sexually reproducing organisms where cells divide to produce sex cells with half the normal number of chromosomes. This ensures genetic variation in offspring. Meiosis takes place in specific cells of an organism with paired chromosomes (diploid cells), leading to the

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Tissue repair involves complex mechanisms like regeneration by parenchymal cells or fibrosis leading to scar formation. Inflammatory cells play a crucial role in tissue repair, along with processes like ECM synthesis and cell migration. Different types of cells in the body have varying regenerative

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The body's response to injury involves two main processes of wound healing - regeneration and repair. Regeneration involves proliferation of parenchymatous cells, while repair results in fibrosis and scarring by proliferation of connective tissue. Different types of cells play varying roles in the h

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The process of hematopoiesis involves the lifelong production, multiplication, and specialization of different blood cells in the bone marrow, starting with the stem cells. This process includes the differentiation and proliferation of various progenitor cells, regulated by hematopoietic growth fact

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The study explores the immunotoxic effects of industrial effluents on fin fish, highlighting xenobiotics' impact on the immune system. It discusses the sensitivity of the immune system to environmental toxins and the elicitation of immune reactions by various substances. The importance of fish as a

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This collection of supplementary figures provides detailed flow cytometry data on immune cell populations, including CD4+ T cells, CD8+ T cells, tumor-associated macrophages, and more. The figures also include information on immune checkpoint molecules like PD-L1 and TIGIT. Each figure presents spec

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Cells are the fundamental units of life, but viruses are an exception as they lack cells. Eukaryotic cells have a defined nucleus with a nuclear membrane housing chromosomes, while prokaryotic cells lack a membrane-bound nucleus and other organelles. Eukaryotic cells are larger, containing membrane-

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Prokaryotic cells divide through binary fission, while eukaryotic cells undergo mitosis with nuclear division and cytokinesis. Prokaryotic cells lack a nucleus and divide by replicating DNA and forming two identical daughter cells. Eukaryotic chromosomes, associated with histone proteins, undergo co

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Stem cell transplantation involves addressing the issue of immune cells failing to recognize and eliminate tumor cells, known as "The Bad Boys." By removing the dormant immune cells and replacing them with new ones from a compatible donor, the therapy aims to empower the immune system to target and

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The small intestine is a key organ in the digestive system responsible for the digestion and absorption of nutrients. It is divided into the duodenum, jejunum, and ileum, each with specific functions and structures like plicae circulares, villi, microvilli, and crypts of Lieberkühn. The intestinal

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Explore the different stages of the immune response, starting with macrophages in the innate immune system that act fast without memory. Follow the path to the spleen and lymph nodes where T cells, already educated at birth to recognize specific antigens, await. Witness the intricate dance of the im

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Pathogens, such as bacteria, viruses, and fungi, can cause infectious diseases in humans, animals, and plants. The immune system defends against these pathogens through various mechanisms, including the production of antibodies, phagocytosis, and the activation of specific defense cells like white b

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The lymphatic system, a vital component of the immune system, consists of lymphocytes, plasma cells, and other cells within a framework of reticular cells and fibers. It includes lymphoid organs like the bone marrow, thymus, lymph nodes, and spleen. Diffuse lymphatic tissue and lymphatic nodules are

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The lymphatic system plays a crucial role in returning leaked fluids back to the blood, protecting the body from foreign materials, and supporting immune surveillance. It consists of lymphoid cells such as T and B lymphocytes, macrophages, dendritic cells, and reticular cells that work together to d

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Stem cells play a crucial role in animal cells, offering the potential to differentiate into various cell types. Totipotent stem cells are the most versatile, capable of developing into any cell type in the embryo, including extra-embryonic cells. Pluripotent stem cells can give rise to all body cel

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Vesatolimod (GS-9620) has shown to be safe and pharmacodynamically active in individuals infected with HIV. Studies demonstrate its potential to eliminate and activate infected CD4 T cells, recruit immune cells like NK cells and macrophages, and work in combination with broadly neutralizing antibodi

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Commercial cells and batteries are essential sources of electrochemical electricity. There are two main types: primary cells, which are one-time use and irreversible, and secondary cells, which are rechargeable and reversible. Examples include dry cells and lead storage cells. The components and rea

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Blood is a complex tissue composed of red cells, white cells, platelets, and plasma, each serving crucial functions such as oxygen transport, waste removal, and immune system support. Red cells contain hemoglobin for oxygen transport, while white cells play a key role in defending the body against i

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Fuel cells are electrochemical cells that generate electricity through reactions between fuel and an oxidizing agent like oxygen. They offer high efficiency compared to traditional power plants. The working of fuel cells involves hydrogen and oxygen reacting to produce electricity. NASA has utilized

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