Histamine is a vital autacoid synthesized and stored in mast cells, playing a key role in various physiological processes and allergic reactions. This article delves into its synthesis, storage, release, and receptors like H1, H2, and H3, along with the pharmacology of antihistamines. Explore the in

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Chemical mediators of inflammation act on blood vessels and cells to contribute to an inflammatory response. These mediators include vasoactive amines like histamine and serotonin, plasma proteases such as the complement, kinin, and clotting systems, and important inflammatory mediators like C3a and

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Histamine, a potent chemical mediator, is synthesized and stored in various cells like mast cells and basophils. It is involved in allergic reactions, immune responses, and neurotransmission in the central and autonomic nervous systems. This substance is released in response to stimuli like tissue i

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Autacoids are locally acting hormone-like substances with intense biological activity produced by various cells in the body. They act briefly at the site of synthesis and release, playing roles in inflammation, vasoactivity, and more. This content delves into the classification, functions, and synth

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Decarboxylation is a crucial reaction in amino acid metabolism where CO2 is removed to form biogenic amines, catalyzed by decarboxylase enzymes. Important biogenic amines include tyramine, tryptamine, and histamine, each impacting physiological functions like blood pressure regulation. Aromatic amin

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The inflammatory response is a crucial defense mechanism of the immune system. It comprises three lines of defense aimed at protecting the body from harmful pathogens. When a barrier is breached, such as by a splinter carrying bacteria, the inflammatory process is initiated. This includes the releas

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Explore the distinctions between drugs and medicines, understanding side effects, and the importance of prescriptions for certain drugs. Learn about common side effects, prescription medicines, prescription drug abuse, and the roles of different types of medications in our body. Gain insights into r

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