Steatotic liver disease, including metabolic dysfunction associated steatohepatitis (MASLD) and metabolic associated alcoholic liver disease (MALD), is a common cause of liver test abnormalities in the United States. Risk factors such as obesity and metabolic syndrome can lead to advanced fibrosis a

2 views • 44 slides

The concept of severity assessment in adverse drug reactions (ADRs) categorizes the intensity of medical events into mild, moderate, severe, or lethal categories based on the required management steps. Various classification systems such as Karch and Lasagna, as well as modified Hartwig's and Siegel

4 views • 10 slides

The natural history of disease development outlines the progression of a disease in an individual without intervention, from exposure to outcome. Learning objectives include defining prevention terms, understanding disease severity, prevention levels, and intervention measures. Studying disease prog

4 views • 16 slides

Acute calculous cholecystitis is a common digestive disease with varying treatment perspectives. The Tokyo Guidelines 2018 provide criteria and severity grading for the diagnosis of acute cholecystitis. Diagnosis involves local and systemic signs of inflammation along with specific imaging findings.

0 views • 18 slides

Epidemiology is the study of disease patterns, factors influencing disease occurrence, and the core functions of surveillance, field investigation, and analytic studies. It involves understanding disease characteristics, natural history, and evaluating the effectiveness of activities to mitigate dis

1 views • 25 slides

Explore hurricane track data from 1981 to 2021 sourced from the International Best Track Archive for Climate Stewardship. The visualization includes maps showcasing hurricane frequency, maximum severity by Saffir-Simpson scale categories, and trend indices. Follow the evolution of hurricane patterns

0 views • 18 slides

Tyzzer's disease is an acute bacterial infection affecting rodents and rabbits, caused by Clostridium piliforme. Discovered in 1917 by Ernest Tyzzer, the disease is characterized by necrotic lesions in the caecal mucosa, liver, and heart. Initially known as Bacillus piliformis, it was later renamed

2 views • 21 slides

This article discusses disease control processes in epidemiology, including reducing disease incidence, duration, and transmission. It covers public policy interventions, elimination, eradication, and extinction of infectious agents. It also highlights preventable causes of disease and different lev

2 views • 10 slides

This case study discusses the diagnosis and severity of intellectual disability (ID) in a 5-year-old boy, distinguishing between developmental delay and ID. It covers the importance of genetic testing, particularly in cases like Fragile X syndrome, as well as the evolution of assessing ID severity b

0 views • 21 slides

Atopic eczema is a chronic inflammatory skin condition in children with varying severity. Proper management is crucial to reduce its impact on a child's life. Identifying triggers, assessing severity, and implementing a stepped treatment approach are key in managing this condition effectively.

0 views • 15 slides

This report delves into the magnitude and severity of gender-based violence (GBV) in the Democratic Republic of the Congo (DRC) in recent years. It highlights the methodology used in data collection, key results, and leveraging findings for advocacy. The report also outlines the objectives of the ma

1 views • 19 slides

Co-occurring mental and physical health disorders are prevalent and require an integrative multidisciplinary approach for effective assessment and treatment. This holistic approach helps address the complexity of managing multiple disorders in an integrated healthcare setting. Through a multi-direct

1 views • 37 slides

Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental condition that affects social interaction, communication, and behavior. The spectrum includes a range of characteristics, from highly verbal individuals to non-verbal ones. Various disorders fall under the ASD umbrella, with different l

0 views • 14 slides

This presentation by Dr. Sneha Shanbhag, a consultant internist at Mount Saint John's Medical Centre in Antigua, outlines the COVID-19 management strategies in the acute care setting. The presentation covers case severity breakdown, hospital admission guidelines, therapeutic management for mild to s

0 views • 10 slides

Chronic primary mitral regurgitation (MR) presents various considerations in evaluating severity, symptoms, left ventricular function, and candidacy for mitral valve repair. The management decision involves assessing imaging findings, LV function, and the impact on mortality and quality of life. Sur

0 views • 9 slides

Patients with coronary artery disease should be screened for peripheral vascular disease as it is a frequent integrator of global cardiovascular risk. The association of atherosclerosis in various arterial diseases highlights the importance of identifying multisite artery disease. The prevalence and

0 views • 23 slides

Periodontal disease, like caries, is multifactorial and influenced by the balance between bacterial challenge and host defense. Nutritional factors play a subtle but significant role in maintaining periodontal health. A deficiency in nutrients can adversely affect the periodontal tissues and modify

0 views • 23 slides

Research findings from NCHRP Project 17-85 focused on assessing current HSM approaches for crash severity prediction, identifying gaps, developing new severity models, and creating guidance for model application. The study introduced distinctive methodologies like Quasi-induced Exposure and Ordered

0 views • 19 slides

The Human Disease Symptom Network (HSDN) is constructed using a large-scale medical bibliographic records database to form a network of human diseases based on symptom similarities. By integrating disease-gene associations and protein-protein interaction data, correlations between symptom similarity

0 views • 37 slides

The British Association of Dermatologists conducted a national clinical audit program in 2015 to evaluate atopic eczema in children based on NICE guidelines. The audit included contributions from BAD and BSPD members, as well as private providers. It involved 128 submissions from 98 centers, with 12

2 views • 18 slides

The supplemental presentation to NCHRP Research Report 1103 explores the influence of vehicle mix on crash frequency and severity. It highlights the project background, objectives, completed tasks, key deliverables, implementation strategies, and considerations for the Highway Safety Manual. The pro

0 views • 43 slides

Columnaris disease, also known as Saddleback disease, is a common bacterial infection in fish that is often brought about by poor handling and high stress levels. This disease manifests as tail and fin rot, leading to rapid fish mortality. The causative organism, Cytophaga (formerly Flexibacter), is

0 views • 21 slides

Patients with sickle cell disease (SCD) often experience painful episodes known as sickle cell crises due to abnormally shaped red blood cells. The severity of SCD can be influenced by genetic and environmental factors, with cold weather being linked to increased pain episodes. Research has shown co

0 views • 27 slides

An overview of crime severity measurements, property crime rates, and violent crime rates in Sooke and comparable detachments. The data includes crime severity index scores, crime type contributions by year, and property/violent crime rates per 1000 population. The analysis shows changes over time,

0 views • 8 slides

Defects in software arise from various causes such as miscommunication, lack of experience, human factors, and poor testing skills. Different types of defects can be classified based on severity, work product, type of error, and status. Severity-wise classification includes major, minor, and fatal d

0 views • 30 slides

Steatosis has emerged as a significant diagnosis with NAFLD becoming a common cause for hepatologic evaluation. Liver stiffness measurement (LSM) using transient elastography is vital for assessing fibrosis severity in NAFLD patients. However, the accuracy of LSM can be influenced by obesity and sev

0 views • 35 slides

Explore the latest findings from the Alzheimer's Disease Genetics Symposium 2019 on disease mechanisms, drug targets, and genetic pathways. Dive into the progress made by the Alzheimer's Disease Genetics Consortium over the past decade. Transition to a Genome-Wide Association Study uncovering suscep

0 views • 42 slides

Clinical studies and model-based analysis provide evidence and categorization of COVID-19 severity, symptoms, and risk factors. Severity stratification shows the distribution among tested patients, highlighting the attack rate and vulnerable populations. Studies aim to estimate severity accurately f

0 views • 33 slides

Christa Anderson, a Senior Security Program Manager at Microsoft's Security Response Center, discusses the importance of gamifying vulnerability report data to encourage coordinated disclosure. The MSRC Top 100, announced at Black Hat USA, plays a crucial role in the public credit strategy by recogn

0 views • 13 slides

Dr. Somen Banerjee, Director of Public Health in London Borough Tower Hamlets, highlights the concerning liver disease mortality rates in the area, with high incidence of cirrhosis, cancer, and hepatitis B and C. The data reveals a significant burden of liver diseases such as Non-Alcoholic Fatty Liv

0 views • 18 slides

Inflammatory Bowel Disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC), chronic conditions with immunologic basis. This article delves into the epidemiology, pathophysiology, and differences between CD and UC, highlighting clinical features, pathology, and complications like a

0 views • 42 slides

The CLEAR Trial is a 2x2 factorial randomized trial evaluating the effectiveness of hypertonic saline and carbocisteine for airway clearance in bronchiectasis patients. The trial, led by Professor Stuart Elborn and Professor Judy Bradley, focuses on pharmacovigilance activities, adverse event defini

0 views • 20 slides

A study by Shen, Xinyi and colleagues from the University of Connecticut has developed the RAdar Produced Inundation Diary (RAPID) algorithm for near real-time flood inundation mapping using Synthetic Aperture Radar (SAR) data from Sentinel-1 during Hurricane Florence. The analysis revealed large in

0 views • 8 slides

A fracture is a break in bone continuity, classified by causal factors, presence of external wounds, location, morphology, severity, and stability post-reduction. Fracture causes include direct violence, indirect violence, bone diseases, and repeated stress. Fractures can be closed or open, with sev

0 views • 17 slides

The Scottish Public Health Observatory is leveraging detailed Electronic Health Records (EHRs) to estimate the burden of disease in Scotland. By tapping into a wealth of EHR data on various health indicators, the study aims to provide a comprehensive analysis of non-fatal and fatal conditions. Main

0 views • 14 slides

Fabry's disease is a rare X-linked lipid storage disorder characterized by deficient lysosomal alpha-galactosidase A activity. This condition primarily affects males, leading to chronic kidney disease and progression to end-stage renal disease. Kidney involvement is a critical aspect, and high doses

0 views • 24 slides

The Columbia Suicide Severity Rating Scale (C-SSRS) is an evidence-based suicide risk screening tool recommended by the Joint Commission. It is vital for identifying patients at risk of suicide, given the alarming rise in suicide rates. This tool helps healthcare professionals assess and address sui

0 views • 8 slides

This project report presents a simple compliance risk assessment template along with post-mitigation judgment, risk severity, risk level, mitigations, warnings, and remedies. It includes information on communication controls, risk severity levels, acceptability judgments, likelihood assessments, and

0 views • 5 slides

Viral pathogenesis involves the process by which a virus leads to disease, exploring the interplay between viral and host factors. It encompasses the concepts of virulence, viral disease, and the effects on infected cells and the host's immune response. Changes within infected cells, including cell

0 views • 26 slides

Phase 3 trials have demonstrated favorable changes in diabetic retinopathy severity in eyes treated with ranibizumab for diabetic macular edema. This study focuses on the 5-year outcomes of ranibizumab therapy in managing diabetic retinopathy progression, especially with decreasing exposure to anti-

0 views • 24 slides