Rare Case of Neonatal Meningitis with Antibiotic Challenge
A term male baby born with perinatal hypoxia developed neonatal meningitis with convulsions. Blood culture revealed Acinetobacter sp. and Pseudomonas sp. Empirical antibiotic therapy was escalated to Colistin and Ceftazidime due to resistance. Subsequent testing showed colonies resembling Pseudomona
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Ceftazidime Dosage Modification in Renal Failure Cases
Ceftazidime dosage adjustments are crucial in patients with renal impairment to prevent toxicity or suboptimal treatment. Factors like renal function, drug elimination route, and therapeutic window must be considered. Proper dosing ensures effective treatment while avoiding adverse effects in patien
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In Vitro Selection of Enterobacter cloacae Resistance Mechanisms with Antibiotics
Study by Mariana Castanheira et al. presented at IDWeek 2020 discusses the generation of diverse resistance mechanisms in Enterobacter cloacae with cefepime, meropenem, and ceftazidime-avibactam. E. cloacae, a significant pathogen causing human infections, exhibits various resistance mechanisms, inc
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