Cardiovascular Disease in HIV
The increased risk of cardiovascular disease in people with HIV and specific strategies to treat it. This presentation discusses potential mechanisms, comorbidity gaps, and the impact of traditional risk factors. Explore the role of inflammation and immune dysfunction in atherosclerosis and vulnerab
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Inflammation and Cholesterol Predicting Cardiovascular Events
This study explores how inflammation and cholesterol levels predict cardiovascular events among 13,970 statin-intolerant patients in the CLEAR Outcomes trial. Findings suggest residual inflammatory risk may be a stronger predictor than residual cholesterol risk for future events. The research analyz
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Understanding Risk Management in Environmental Geography and Disaster Management
Risk management in environmental geography and disaster management involves assessing the potential losses from hazards, evaluating vulnerability and exposure, and implementing strategies to mitigate risks. It includes calculating risk, dealing with risk through acceptance, avoidance, reduction, or
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Insights from the REPRIEVE Trial for Managing Cardiovascular Risk in Patients with HIV
Cardiovascular disease is a growing concern in individuals living with HIV, despite advancements in treatment. The REPRIEVE Trial sheds light on the importance of assessing cardiovascular risk and implementing primary prevention measures in this population. Dr. Grinspoon's financial disclosures and
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Understanding the Natural History of Disease Development and Prevention
The natural history of disease development outlines the progression of a disease in an individual without intervention, from exposure to outcome. Learning objectives include defining prevention terms, understanding disease severity, prevention levels, and intervention measures. Studying disease prog
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The REPRIEVE Trial: Developing Cardiovascular Disease Prevention Strategy for People Living with HIV
The REPRIEVE trial focuses on developing a cardiovascular disease prevention strategy for individuals living with HIV. It addresses the increased risk of CVD in this population, even with good viral suppression. The study evaluates the use of pitavastatin, a statin with anti-inflammatory properties,
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Pediatric Cardiovascular Exam Overview
Explore the differences between pediatric and adult cardiovascular exams, highlighting key differences in disease patterns, examination approaches, and objectives. Learn about the importance of distinguishing between routine well-baby exams and evaluations of ill children, along with step-by-step gu
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CLEAR Outcomes Trial: Bempedoic Acid for Cardiovascular Prevention
The CLEAR Outcomes Trial investigated the effects of bempedoic acid, an ATP citrate lyase inhibitor, on cardiovascular outcomes in primary prevention patients. Results showed a reduction in cardiovascular events with bempedoic acid, particularly in patients intolerant to statins. Baseline characteri
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Effects of Exercise on the Cardiovascular System
Exploring the immediate and long-term effects of exercise on the cardiovascular system reveals the remarkable adaptations and responses the body undergoes. From short-term increases in heart rate and blood pressure to long-lasting changes in cardiac output, exercise plays a crucial role in enhancing
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Project Risk Management Fundamentals: A Comprehensive Overview
Project risk management involves minimizing potential risks and maximizing opportunities through processes such as risk management planning, risk identification, qualitative and quantitative risk analysis, risk response planning, and risk monitoring and control. Quantitative risk analysis assesses t
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Impact of Diet on Cardiovascular Health
The impact of diet on the cardiovascular system is significant, with a high intake of LDL leading to clogged arteries and increased risk of Coronary Heart Disease. Regular exercise brings about positive changes in the cardiovascular system, enhancing heart function and oxygen delivery. Immediate ben
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Residual Inflammatory and Cholesterol Risks in Atherosclerosis Patients
In a secondary analysis of the CANTOS study, researchers evaluated the impact of residual inflammatory risk and residual cholesterol risk in a large cohort of atherosclerosis patients already receiving lipid-lowering therapy. Results showed the relative contributions of inflammation and cholesterol
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Morphologic and Physiologic Connections in Blood Pressure Waveforms for Cardiovascular Event Prediction
This report discusses the morphologic and physiologic connections in continuous blood pressure waveforms and their association with incident cardiovascular events. The study aims to assess if changes in arterial elasticity contribute to predicting CVD events and explores additional measures derived
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Cluster Randomised Controlled Trial for Cardiovascular Disease Risk in Severe Mental Illness
A cluster randomised controlled trial is being conducted to test an intervention aimed at reducing cardiovascular disease risk for individuals with severe mental illnesses in primary care settings. Led by Professor David Osborn at UCL Division of Psychiatry, the study is funded by the National Insti
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The Importance of Addressing Cardiovascular Disease in Maternal Health
Cardiovascular disease remains a significant contributor to maternal mortality in the UK, with maternal deaths from cardiac issues outnumbering those from other direct causes, except thrombosis. The prevalence of cardiovascular risk factors in pregnant women, combined with a lack of consideration fo
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Screening for Peripheral Vascular Disease in Patients with Coronary Artery Disease
Patients with coronary artery disease should be screened for peripheral vascular disease as it is a frequent integrator of global cardiovascular risk. The association of atherosclerosis in various arterial diseases highlights the importance of identifying multisite artery disease. The prevalence and
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Prevalence of Cardiovascular Disease in Adult ESRD Patients: 2016 Data Report
The data report examines the prevalence of cardiovascular diseases in adult End-Stage Renal Disease (ESRD) patients in 2016 by treatment modality and age. It includes information on various cardiovascular conditions such as atrial fibrillation, acute myocardial infarction, coronary artery disease, a
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Human Disease Symptom Network: Understanding Disease Relationships Through Symptoms and Genes
The Human Disease Symptom Network (HSDN) is constructed using a large-scale medical bibliographic records database to form a network of human diseases based on symptom similarities. By integrating disease-gene associations and protein-protein interaction data, correlations between symptom similarity
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Understanding Cardiovascular Changes in Pregnancy
This informative content discusses the normal physiological changes of the cardiovascular system in pregnancy, symptoms and signs of cardiovascular disease, the impact of pregnancy on cardiovascular health, and the management of cardiovascular issues during pregnancy, labor, and the postpartum perio
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Understanding Cardiovascular Drugs: An Overview of Treatment Options
Explore the world of cardiovascular drugs, including antihypertensive, antianginal, heart failure, antiarrhythmic, diuretic, antithrombotic, and antihyperlipidemic medications. Dive into the mechanisms of action, clinical indications, and adverse effects of these drugs, gaining valuable insights int
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Understanding Risk Concepts and Management Strategies in Finance
Explore the essential concepts of risk in finance, such as risk definition, risk profiles, financial exposure, and types of financial risks. Learn about risk vs. reward trade-offs, identifying risk profiles, and tools to control financial risk. Understand the balance between risk and return, and the
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Risk Management & MPTF Portfolio Analysis at Programme Level for UN Somalia
This session delves into the world of risk management and portfolio analysis at the programme/project level, specifically focusing on the Risk Management Unit of the United Nations Somalia. It covers enterprise risk management standards, planned risk management actions, the role of RMU, joint risk m
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High-Sensitivity Cardiac Troponin in Stable Ischemic Heart Disease
Study by Nicholas Marston, MD, and team shows that high-sensitivity cardiac troponin at any detectable concentration is linked to a higher risk of major cardiovascular events in patients with stable ischemic heart disease. The research, conducted through the PEGASUS-TIMI 54 trial, aimed to further u
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Healthy Eating Guidelines for Common Health Conditions
Planning meals for individuals with cardiovascular disease, dental disease, diabetes, and obesity involves choosing the right foods from each food group, using healthy cooking methods, and avoiding excessive fats and sugars. For cardiovascular and dental health, emphasizing low-fat options, avoiding
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Baseline Lipoprotein(a) Levels in Statin-Treated Patients for Cardiovascular Event Prediction
Lipoprotein(a) levels play a crucial role in cardiovascular disease risk assessment, especially in patients undergoing statin therapy. This individual patient-data meta-analysis from the Lancet explores the predictive value of lipoprotein(a) levels in 29,069 patients across seven landmark statin tri
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Association of Fruit, Vegetable, and Legume Intake with Cardiovascular Disease and Mortality
The study conducted by the PURE investigators examined the relationship between fruit, vegetable, and legume consumption and cardiovascular disease (CVD) and mortality in a cohort of 135,335 individuals from 18 countries. Dietary guidelines recommend at least 5 daily servings of these foods, which h
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Evolution of Glucose-Lowering Therapies in Primary Care Settings
Cardiovascular effects of older glucose-lowering therapies and the history of cardiovascular outcome trials are discussed in this educational slide module. It outlines the timeline of treatment options from the discovery of insulin to the introduction of various medications. Evidence regarding the c
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Investigating the Impact of Weekly Incretin on Cardiovascular Events in Diabetes
Individuals with type 2 diabetes have an increased risk of cardiovascular events compared to those without the condition. Research indicates that certain GLP-1 receptor agonists have shown promising results in reducing cardiovascular events in diabetic patients with specific HbA1c levels. However, t
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Clinical Trial Results of Rivaroxaban in ACS Patients: ATLAS-ACS 2 Study
The ATLAS-ACS 2 study investigated the efficacy and safety of rivaroxaban in ACS patients post-index event. The primary endpoints included cardiovascular death, MI, and stroke, with significant reductions seen with rivaroxaban compared to placebo. Stent thrombosis was also reduced with rivaroxaban t
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Understanding Heart Health and Disease Prevention Through Diet
Heart disease is a prevalent global issue, with cardiovascular diseases leading to millions of deaths annually. Lifestyle modifications, including dietary changes, play a crucial role in managing heart health. Despite being mostly preventable, cardiovascular disease remains a significant cause of mo
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GripTrack: Innovative Device for Monitoring Elderly Health
GripTrack is a portable grip strength monitoring device designed to track cardiovascular and musculoskeletal health in the elderly population. It aims to provide an accurate early warning system by assessing grip strength, which can indicate cognitive decline, cardiovascular health, and frailty synd
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Understanding the Cardiovascular Effects of Air Pollution in Vulnerable Populations
This presentation discusses the significant cardiovascular effects of air pollution, particularly on vulnerable populations such as older adults, women, and Latinos. It highlights the environmental factors contributing to cardiovascular health disparities and emphasizes the nursing implications for
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Developing a Risk Appetite Culture: Importance and Framework
Risk management plays a critical role in the success of corporations, with strategy and risk being intertwined. This presentation delves into definitions of key terms such as risk appetite, the Risk Appetite Cycle, characteristics of a well-defined risk appetite, and the importance of expressing ris
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Understanding the Cardiovascular System: Anatomy, Physiology, and Function
Explore the intricate workings of the cardiovascular system, encompassing the heart, blood vessels, and blood circulation. Learn the anatomy, physiology, and function of this vital system, including the roles of arteries, veins, capillaries, and red and blue blood. Understand how the cardiovascular
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Understanding Cohort Studies and Disease Risk in Epidemiology
Cohort studies play a crucial role in epidemiology, allowing researchers to assess the relationship between exposure and disease risk. By describing different study designs, calculating risks, and understanding population at risk, valuable insights are gained to prevent adverse health outcomes. Risk
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Cardiovascular Disease in End-Stage Renal Disease Patients: Data Analysis 2011-2013
Understanding the prevalence and causes of cardiovascular diseases in patients with End-Stage Renal Disease (ESRD) is crucial for effective management. This report analyzes data from 2011-2013, focusing on the causes of death in ESRD patients, prevalence of cardiovascular diseases by treatment modal
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Insights on Cardiometabolic Risk Reduction and Diabetes Treatment in 2019
Cardiologists in 2019 must address the significant cardiovascular risks associated with diabetes mellitus. Dr. Keith C. Ferdinand highlights the increased rates of heart disease, stroke, and heart failure in patients with diabetes. Despite advancements, cardiovascular risk management remains subopti
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Cardiovascular Disease Prevention Fellowship Programme Information Pack
The Cardiovascular Disease Prevention Fellowship Programme by Health Innovation Network offers a comprehensive 7-month program for healthcare professionals to enhance their skills in cardiovascular disease prevention. The program includes clinical webinars, improvement collaborative sessions, and qu
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The Evolving Role of Cardiovascular Clinicians in Managing Type 2 Diabetes Risk
The role of cardiovascular clinicians in managing cardiovascular risk in patients with type 2 diabetes is evolving, with a growing emphasis on collaboration with multidisciplinary teams. Recognizing the potential benefits of certain diabetes medications on cardiovascular outcomes, clinicians are urg
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Understanding PCSK9 Inhibitors for Cardiovascular Health
PCSK9 inhibitors are a novel class of medications that help lower LDL cholesterol levels, reducing the risk of cardiovascular events. This article covers their mechanism of action, patient groups benefiting from them, efficacy in LDL-C lowering, and safety considerations. Learn how PCSK9 inhibitors
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