Guide for Multi-Month Dispensation of ARV Medications for Adolescents Living with HIV
This guide provides assistance to healthcare providers, social workers, and counselors in discussing Multi-Month Dispensation (DMM) of antiretroviral medications with adolescents living with HIV. It offers a structured approach to engage adolescents in conversations about ARV treatment, aims to faci
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ART Access System Overview in Health Ministry
The ART Access System, implemented by the Ministry of Health, is an electronic tool for client and stock management using the CRPDDP approach. It integrates with EMR systems and involves various stakeholders like health facility staff, pharmacy staff, ART clinicians, and more. Accessible through a w
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Resistance Analysis of Long-Acting Lenacapavir in HIV Treatment: 104-Week Findings
Study on long-acting lenacapavir in heavily treatment-experienced HIV individuals after 104 weeks revealed emergence of lenacapavir resistance-associated mutations. Lenacapavir, a potent HIV-1 capsid inhibitor, has shown activity against ARV-resistant strains. The CAPELLA study analyzed lenacapavir
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Insights from PROMISE 1077 Trials on Maternal-Infant Survival
The PROMISE 1077 Trials focused on key research questions related to the effectiveness and safety of antiretroviral therapy in HIV+ pregnant women, especially concerning maternal ART during antepartum and postpartum stages, as well as the impact on maternal health post-pregnancy. The trials recruite
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Comparison of NNRTI vs NNRTI and DRIVE-AHEAD Study: DOR/3TC/TDF vs EFV/FTC/TDF
The comparison study explores NNRTI regimens alongside the DRIVE-AHEAD trial, focusing on DOR/3TC/TDF vs EFV-FTC/TDF. DRIVE-AHEAD assesses the efficacy and safety of DOR in ARV-naïve HIV patients, aiming for non-inferiority based on virologic response, with DOR exhibiting potential neuropsychiatric
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Dolutegravir-Lamivudine Dual Therapy in ARV-Naïve HIV Patients: 48-Week Results of PADDLE Trial
The PADDLE trial evaluated the efficacy, safety, and tolerability of a Dolutegravir-Lamivudine regimen as initial therapy in HIV-infected, treatment-naïve patients. This pilot study demonstrated comparable viral load changes to triple therapy, supporting the use of this dual regimen. The study desi
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Loneliness and ARV Adherence among People Living with HIV in Ontario, Canada
This study investigates the impact of loneliness on antiretroviral medication adherence among individuals living with HIV in Ontario. Utilizing the Ontario HIV Cohort Study, researchers assessed loneliness levels and adherence through questionnaires, finding associations between loneliness severity
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