UK Survey on Endovascular Treatment of Acute Pulmonary Embolism
Acute pulmonary embolism (PE) is a significant issue in hospitalized patients, with current treatments focusing on anticoagulation and systemic thrombolysis. Surgical treatments have shown poor outcomes, leading to a rise in endovascular techniques aimed at reducing clot burden. A survey conducted i
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Understanding Paroxysmal Nocturnal Hemoglobinuria (PNH)
Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare blood disorder characterized by the destruction of red blood cells in the bloodstream, leading to anemia, hemoglobinuria, jaundice, and other symptoms. It is often challenging to diagnose due to its rarity. PNH can be a thrombophilic state, causing
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Guidelines for Thrombophilia Testing in Venous Thromboembolism Management
The American Society of Hematology (ASH) provides comprehensive guidelines for the management of venous thromboembolism (VTE) with a focus on thrombophilia testing. Expert panels develop recommendations based on clinical questions, evidence synthesis, and resource use. These guidelines cover various
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Efficacy and Safety of Anticoagulation with Edoxaban in Patients with AHRE Durations ≥24 Hours: The NOAH-AFNET 6 Trial
A prespecified subanalysis of the NOAH-AFNET 6 trial evaluated the efficacy and safety of edoxaban anticoagulation in patients with Atrial High-Rate Episodes (AHRE) lasting 24 hours compared to shorter episodes. Findings suggest that oral anticoagulation with edoxaban does not significantly reduce t
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Understanding Antiplatelet and Anticoagulation Therapy in Cardiology
This informative content covers the current practice guidelines and medication options for antiplatelet therapy in CAD patients, discussing different medications, optimal duration of therapy, CV risk assessment, and anticoagulation options in atrial fibrillation. It delves into the role of aspirin i
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Case Report: Submassive Bilateral Pulmonary Embolism in a 69-Year-Old Female
Anne Knisely, a 69-year-old female with a history of endometrial cancer, presented with left leg pain, pleuritic chest pain, and shortness of breath. Imaging revealed extensive bilateral pulmonary emboli, right heart strain, and lower extremity deep vein thrombi. She was managed with anticoagulation
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Optimal Management of Anticoagulation Therapy - ASH 2018 Guidelines
The American Society of Hematology (ASH) 2018 guidelines focus on the optimal management of anticoagulation therapy, specifically in the context of venous thromboembolism (VTE). The guidelines cover topics such as prevention, treatment, and management strategies, developed through thorough panel for
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Guidelines for Management of Pediatric Venous Thromboembolism
This educational slide set presents the American Society of Hematology's 2018 guidelines for the treatment of pediatric venous thromboembolism. The guidelines cover various aspects such as prevention, treatment, and optimal management of anticoagulation therapy in pediatric patients. Panels were for
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Optimal Management of Anticoagulation Therapy: ASH 2018 Guidelines
Educational slide sets and clinical guidelines by the American Society of Hematology (ASH) provide recommendations for the management of venous thromboembolism, including the optimal use of anticoagulation therapy. The guidelines detail panel formation criteria, development process, evidence synthes
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Advances in Anticoagulation Therapy for Cancer-Related VTE and Stroke
Recent studies have shown advancements in anticoagulation therapy for cancer patients with venous thromboembolism (VTE) and stroke prevention. Direct oral anticoagulants (DOACs) are now considered beneficial for treating VTE in cancer, offering advantages in administration and efficacy. Different an
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Treatment Strategies for Recurrent Venous Thromboembolism in Factor V Leiden Patients
This presentation discusses the treatment options for recurrent venous thromboembolism in patients with Factor V Leiden mutation. It explores the pathophysiology, epidemiology, and diagnosis criteria for Factor V Leiden, reviews failed anticoagulation history, and suggests outpatient anticoagulation
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Three-Year Outcomes of Left Atrial Appendage Closure vs. Oral Anticoagulation in Atrial Fibrillation
The PRAGUE-17 study compares the three-year outcomes of left atrial appendage closure (LAAC) versus direct oral anticoagulation in patients with atrial fibrillation. LAAC was found to be non-inferior to NOACs for the primary composite endpoint, with similar incidence rates for secondary endpoints. T
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Perioperative Anticoagulation in Atrial Fibrillation Patients
A thorough exploration of perioperative bridging anticoagulation in patients with atrial fibrillation, discussing the benefits of anticoagulation, therapeutic options, comparison of literature, and application in moderate-risk patients. The use of warfarin in atrial fibrillation treatment, standard
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Transition from Prothrombinex-VF to Beriplex: Information and Guidance
In mid-2024, Prothrombinex-VF will be replaced by Beriplex, with the transition occurring in two stages. Beriplex P/N will be interim until Beriplex AU is available, with identical compositions. Clinicians are provided with dosing guidance for Beriplex, and the WA Anticoagulation Chart has been upda
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Best Practices for Transradial Angiography and Intervention
This update highlights best practices for transradial angiography and intervention, including topics such as ultrasound guidance for transradial access, ulnar artery access recommendations, and future study opportunities. The importance of developing proficiency with ultrasound guidance, utilizing r
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Understanding Cardiac Utilization of Novel Oral Anticoagulants
Dive into the realm of cardiac anticoagulation, exploring the evolution from traditional methods like Warfarin to the modern use of Novel Oral Anticoagulants (NOACs). Discover the indications for long-term anticoagulation in conditions like atrial fibrillation and mechanical heart valves. Delve into
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