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Mrs. NP, a 55-year-old woman with a background of cirrhosis from heavy alcohol use, presented to the ED with symptoms suggestive of sepsis. Examination revealed a febrile state, elevated blood pressure, and altered mental status. Investigations were initiated to determine the cause, with differentia

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Lipids are a diverse group of organic compounds that include fats, oils, hormones, and components of cell membranes. They are vital for energy storage, structural roles in cell membranes, hormone synthesis, and organ protection. Lipids can be classified into different types such as waxes, triglyceri

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Explore the major metabolic pathways of glucose, including glycogenolysis, gluconeogenesis, glycolysis, and more. Understand the production, utilization, catabolic, and anabolic cycles of glucose in cellular metabolism. Learn about key concepts such as hexose interconversion, HMP/PPP, Krebs cycle, a

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This content covers various sports injuries, ways to reduce risks, treatment of injuries including R.I.C.E method, and different drugs used in sports like anabolic steroids, beta blockers, peptide hormones, and the concept of blood doping. It also touches upon benefits, risks, and examples related t

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Creating an effective daily respiratory therapy regimen is crucial for adults with Cystic Fibrosis (CF) to maintain healthy lungs and good lung function. This includes inhaled medications such as nebulizer treatments and bronchodilators, airway clearance techniques like the Vest and Pep devices, as

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Anabolic steroids, beta-blockers, diuretics, narcotic analgesics, and peptide hormones are commonly used in sports to enhance performance. Each drug has specific advantages and disadvantages, impacting athletes' physical and mental health. While some drugs enhance muscle growth and speed up recovery

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Recent studies delve into the impact of different steroids on mortality and organ support in hospitalized COVID-19 patients. The use of dexamethasone showed a significant reduction in 28-day mortality, especially in patients requiring oxygen support. On the other hand, the REMAP-CAP trial assessed t

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Explore the role of rescue therapy in COPD management, including the use of antibiotics and steroids, to address exacerbations and improve quality of life. Learn about the benefits, guidelines, and criteria for identifying patients who may benefit from home rescue courses. Discover how antibiotic th

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This unit delves into the composition, chemistry, therapeutic uses, and commercial applications of secondary metabolites such as steroids, cardiac glycosides, and triterpenoids. It explores the properties of saponin glycosides, their classification based on aglycone nature, and the significance of s

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Metabolism in living organisms involves anabolism and catabolism, where anabolism generates essential biomolecules for growth using energy, while catabolism breaks down nutrients for energy release. Anabolic processes include synthesis of carbohydrates, lipids, proteins, nucleic acids, and other gro

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Exploring the diverse world of secondary metabolites, this content delves into the composition, chemistry, biosources, therapeutic uses, and commercial applications of various compounds such as Alkaloids, Flavonoids, Steroids, Glycosides, and more. It discusses the structural characteristics, biolog

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Post Cycle Therapy (PCT) refers to a specific protocol of drugs and supplements that help restore your body's natural hormonal balance after a cycle of anabolic steroid use. The main goal of PCT is to kickstart your body's own testosterone production

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Bacterial and fungal corneal ulcers, known as suppurative keratitis, are a significant cause of blindness, included in national blindness control programs. They result from infections by exogenous organisms like S. aureus, S. pneumoniae, Aspergillus, and Candida. Predisposing factors include trauma,

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Exploring the intricate world of metabolism, this topic delves into the chemical reactions within organisms. From anabolic to catabolic pathways, enzymes play a crucial role in controlling these processes. Learn about reversible and irreversible reactions, alternative pathways, and the vital role of

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Explore the role of Steroids, Cardiac Glycosides, and Triterpenoids in pharmacognosy and phytochemistry, focusing on their general introduction, composition, chemistry, biosources, therapeutic uses, and commercial applications. Learn about the structure and attachment of sugar parts in Cardiac Glyco

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Indole alkaloids are a significant group of naturally occurring compounds with diverse chemical structures and physiological actions. This unit delves into the general introduction, composition, chemistry, biosources, therapeutic uses, and commercial applications of various secondary metabolites, in

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Systemic steroids, potent immunosuppressive and anti-inflammatory agents, play a crucial role in dermatological therapy. This article discusses the pharmacology, mechanism of action, cellular effects, and clinical applications of glucocorticoids. It covers topics such as cortisol synthesis, glucocor

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A 54-year-old man with a persistent cough prompts consideration of initial investigations like chest X-ray and pulmonary function tests. For a 40-year-old woman with a persistent cough, initial management options include sequential trials of steroids, a proton pump inhibitor, and nasal spray. These

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Pityriasis Rosea is a benign viral exanthem presenting with a herald patch and generalized eruption, often accompanied by pruritis. Treatment involves reassurance, topical steroids, and oral antihistamines, and usually resolves within 12 weeks. Seborrheic Dermatitis is a papulosquamous disorder char

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The British Association of Dermatologists conducted a national clinical audit program in 2015 to evaluate atopic eczema in children based on NICE guidelines. The audit included contributions from BAD and BSPD members, as well as private providers. It involved 128 submissions from 98 centers, with 12

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Delve into the world of secondary metabolites found in Ruta graveolens, commonly known as Rue or Garden Rue. Discover its rich composition of alkaloids, phenylpropanoids, flavonoids, steroids, cardiac glycosides, triterpenoids, volatile oils, tannins, resins, glycosides, iridoids, and other terpenoi

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Lipids are a diverse group of compounds crucial for various biological functions. They include fats, oils, steroids, and waxes with unique properties essential for energy storage, insulation, and nerve function. Knowledge of lipid biochemistry is pivotal in understanding areas like obesity, diabetes

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This case study delves into a challenging scenario where a hepatologist grapples with a patient presenting HLH associated with liver injury in the context of sarcoidosis. Despite inconclusive initial investigations, further work-up reveals indications of secondary HLH/MAS. The management involves a

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Anabolic steroids, despite potential benefits in medical conditions, pose serious health risks when abused. They can lead to rapid muscle gain, mood swings, infertility, and long-term issues such as high blood pressure, diabetes, and increased risk of stroke. Withdrawal symptoms like depression and

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Clinical guidelines for treating acute otitis externa recommend using topical antibiotic/steroid drops based on the severity of symptoms. This review explores the effectiveness of this treatment approach compared to using only topical antibiotic drops in primary care settings. Search strategies in m

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Dr. Craig Masson, a GP in Clarkston, East Renfrewshire, discusses prescribing and non-prescribing options for hay fever, sinusitis, prickly heat, urticaria, and Lyme disease. The content covers the challenges of managing hay fever symptoms including grass and pollen allergies, and suggests non-pharm

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Lipids, introduced by German biochemist Bloor in 1943, are essential components with high energy value. They include fats, oils, waxes, steroids, and more, with unique chemical properties making them hydrophobic. Lipids are organic compounds containing carbon and vary in structure, affecting their p

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The NCAA annually disseminates a list of banned drug classes and provides drug education to student-athletes, including mid-year transfers. Drug testing programs focus on prevention and safety, with sanctions in place to uphold competitive balance. Testing includes steroids, stimulants, and recreati

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Explore the functions of the sympathetic and parasympathetic nervous systems, the distinct effects they have on various organs, and the differences between anabolic and catabolic responses. Learn about the specific organs supplied by each division and how their activation impacts bodily functions. G

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Glycoside compounds play a significant role in various biological processes, with groups like steroids and cardenolides showcasing notable medicinal effects. Steroids are crystalline substances with specific solubility characteristics, while cardenolide glycosides are known for their toxic effects o

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The endocrine system plays a crucial role in regulating reproductive processes by secreting hormones that influence cellular activity. This system involves ductless glands like the hypothalamus, pituitary gland, and other endocrine glands working together in a feedback mechanism. Hormones of various

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Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP) is a condition that affects pregnant individuals, typically in the late third trimester or immediately postpartum. It manifests as intensely itchy raised areas of papules and plaques mainly on the abdomen, with potential spread to other bo

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In this guide, you will find key facts about paediatric eczema, tips for treatment in primary care, and advice on managing atopic eczema in the community. From using topical steroids effectively to recommending proper skincare routines and avoiding irritants, this resource covers essential informati

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