Impact of Raft Association of NF155 on Microglial Cells' Inflammatory Response

Multiple sclerosis (MS) is a neurodegenerative disease affecting millions globally by causing myelin loss in the CNS axons. This study investigates the role of NF155 raft association in the inflammatory response of microglial cells, shedding light on potential treatment strategies for MS. Liposome treatments and cell culturing techniques were utilized, resulting in significant findings detailed in the results.

• MS Research
• Inflammatory Response
• NF155 Raft Association
• Microglial Cells
• Liposome Treatments

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Uploaded on Sep 28, 2024 | 0 Views

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1. IMPACT OF RAFT ASSOCIATION OF NF155 ON THE INFLAMMATORY RESPONSE OF MICROGLIAL CELLS

2. BACKGROUND MS is a neurodegenerative disease that effects more than 2.3 million people worldwide. Which is characterized by the loss of myelin on the axons of the CNS Bionews Texas

3. BACKGROUND Coogan et al Adapted from Dupree et al

4. BACKGROUND Karperien et al

5. PRIOR RESEARCH Maier et al 2007

6. EXPERIMENT LIPOSOMES Treatments Protein Free, non-raft liposome NF155 and control protein, non-raft liposome NF155, raft liposome NF155 and control protein, raft liposome Adapted from Patil & Jadhav

7. EXPERIMENT CELL CULTURING & ELISA QIAGEN

8. EXPERIMENT CELL PROLIFERATION ASSAY & IMMUNOCYTOCHEMISTRY Br Adapted from Leinco Adapted from atdbio

9. RESULTS EMBL