Understanding Diffusion MRI: Techniques and Applications
Explore the principles of diffusion MRI, from field gradients to diffusion encoding, and learn about water self-diffusion in the brain. Discover how diffusion coefficients and gradient orientations affect signal measurements for diffusion imaging studies.
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Presentation Transcript
Introduction to diffusion MRI Robert Frost
Field gradients ?(?) = ??(?)
Reverse diffusion gradient Refocus
Reverse diffusion gradient Not fully refocused
Reverse diffusion gradient Refocusing of spins diffusing perpendicular to gradient
Diffusion encoding Measure a reduced signal when spins diffuse along the direction of the diffusion gradient Measure less signal if there is more diffusion Can measure diffusion in different directions by repeating the experiment with different diffusion gradient orientations
Water self-diffusion in the brain Diffusion coefficient, ?~10 3??2/? ????= 2??~10?? in 50ms anisotropic isotropic
