The NIH Peer Review Process

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The Center for Scientific Review (CSR)
receives
 all NIH grant applications
 
Refers
 applications to CSR or NIH institute
scientific review groups 
for review 
of
scientific merit
 
Refers
 applications to one or more NIH
institutes or centers (IC) for funding
 
 
Administers the 
review
 
of scientific merit of
most NIH research applications
Study section in CSR review 76% of all NIH grant
applications = ~61,000 applications a year
 
CSR study sections are 
not
 IC specific
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Determines if your application is
On time
Formatted correctly
Complete
Compliant with NIH policy
 
Assigns your application to
Institute(s) or center for funding consideration
Review group for review of scientific and technical merit
 
If you have questions during these stages, please reach out to DRR:
csrdrr@mail.nih.gov
Institutes or Centers based on
Overall mission and guidelines of the IC 
(Institute/Center)
Specific programmatic mandates and interests of the IC
Applications can only be assigned to ICs participating in the FOA
 
Scientific review groups based on
Specific, published review guidelines for each review group
Suggestions made in the Assignment Request Form are considered
 
Referral Process:
DRR        Referral Officers        Branch Chiefs       SROs        Applicant
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ENQUIRE:  Overview and details
https://public.csr.nih.gov/StudySections/CSREnquire
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Behavioral Genetics and Epidemiology (BGES)
Biostatistical Methods and Research Design (BMRD)
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Clinical Research & Field Studies of Infectious Disease* (CRFS)
Infectious Diseases, Reproductive Health, Asthma and Pulmonary
Conditions* (IRAP)
Kidney, Nutrition, Obesity, and Diabetes (KNOD)
Neurological, Aging and Musculoskeletal Epidemiology* (NAME)
     (*and overflow SEPs)
 
Revised scope after 2022 review meetings:
Genetics of Health and Disease (GHD)
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Cancer and Hematological
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Cardiovascular and
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(CRD)
Kidney, Endocrine, and
Digestive Disorders (KEDD)
Neurological, Mental, and
Behavioral Health (NMBH)
Lifestyle and Health
Behaviors (LHB)
Social and
Environmental
Determinants of
Health (SEDH)
Analytics and Statistics for
Population Research panel A (ASPA)
Analytics and Statistics for
Population Research panel B (ASPB)
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Scope: 
reviews applications that seek to understand the etiology,
determinants, distribution and outcomes of cancer and hematologic
disorders, conditions and phenotypes from a population health
perspective.
Topics:
I
ncidence, prevalence, progression and consequences of cancers in large
populations including the focus on early detection, survivorship and
recurrence
Incidence, prevalence, progression and consequences of hematologic disease
and phenotypes in large populations, including but not limited to anemias,
disorders of coagulation, lymphomas and leukemias
E
ffects of environmental and other exposures on incidence, progression, and
outcomes related to cancer and hematologic disorders in large populations
I
ncidence, prevalence and determinants of co-morbidities and multi-
morbidities in populations with cancer and hematological disorders
 
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Scope: 
reviews applications that seek to understand the etiology,
determinants, distribution and outcomes of 
cardiovascular and respiratory
phenotypes, disorders and diseases from a population health perspective
.
 
Topics:
I
ncidence, prevalence, progression and consequences of 
cardiovascular and
disorders 
in large populations that include but are not limited to heart failure,
atherosclerosis, pulmonary vascular disease and myocardial infarction
I
ncidence, prevalence, progression and consequences of respiratory diseases and
disorders in large populations that include but are not limited to chronic
obstructive pulmonary disease (COPD), asthma, and bronchopulmonary dysplasia
E
ffects of environmental and other exposures on incidence, progression, and
outcomes related to cardiovascular and respiratory health in large populations,
especially with a focus on the disease or disorder outcome rather than the
exposure
Incidence, prevalence and determinants of co-morbidities and multi-morbidities in
populations with cardiovascular and respiratory diseases
 
 
 
 
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:
https://public.csr.nih.gov/StudySections
Not required
Suggest assignments
(study section and
institute)
Identify potential conflicts
of interest
List areas of expertise
needed to evaluate the
application
 
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Speak freely! This form will not be part of the assembled application; it will
not be made available to program or to reviewers.
Before you submit your application
 
A program officer (PO) at an NIH Institute or Center
Scientific review officer (SRO)
CSR Division of Receipt and Referral (
csrdrr@mail.nih.gov
)
 
After you submit
 
Your 
SRO
CSR Division of Receipt and Referral
 (
csrdrr@mail.nih.gov
)
 
After 
your review
 
Your 
assigned
 
PO
 
Grants Info
: GrantsInfo@od.nih.gov – 301 945-7573
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Established Investigators can serve
as Ad Hoc or Regular Members –
say yes when invited!
Early career scientists can enroll in
CSR’s early career reviewer (ECR)
program.
ECR’s serve one time and review 2
applications as Reviewere#3.
F
or ECR qualifications and
application process.
https://public.csr.nih.gov/ForRevie
wers/BecomeAReviewer/ECR
Aimed at early career, independent scientists – postdocs are not eligible
and tenured professors are not eligible
Review experience and successful competition for an R01 or equivalent are
disqualifiers.
 
Webinars - Early Career Reviewer Panel Q & A and Grants 101 -
https://public.csr.nih.gov/NewsAndPolicy/PeerReviewVideos
Sample applications at 
https://www.niaid.nih.gov/grants-
contracts/sample-applications
 
 
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The NIH Peer Review Process, including the role of the Center for Scientific Review (CSR) in receiving, referring, and reviewing grant applications. Understand how applications are assigned to institutes or centers and the importance of scientific and technical merit in the review process.

  • NIH Peer Review
  • Grant Applications
  • Scientific Merit
  • Funding Consideration
  • Referral Process
  • Assignment Guidelines
  • Study Sections
  • CSR Enquire

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  1. The NIH Peer Review Process Denise Wiesch, Ph.D., M.P.H Ramona Gianina Dumitrescu, Ph.D., M.P.H. (CHD) Mohammed Elfaramawi M.D, Ph.D., M.P.H. (CRD) Scientific Review Officer Cancer and Hematologic Disorders (CHD) Study Section Epidemiology and Population Health (EPH) Branch Division of AIDS, Behavioral and Population Sciences Center for Scientific Review, NIH

  2. National Institutes of Health 2

  3. 24 NIH Institutes and Centers Fund Grants

  4. Role of CSR: Receipt & Referral, Review The Center for Scientific Review (CSR) receives all NIH grant applications Refers applications to CSR or NIH institute scientific review groups for review of scientific merit Refers applications to one or more NIH institutes or centers (IC) for funding Administers the review of scientific merit of most NIH research applications Study section in CSR review 76% of all NIH grant applications = ~61,000 applications a year CSR study sections are not IC specific

  5. CSRs Division of Receipt and Referral Determines if your application is On time Formatted correctly Complete Compliant with NIH policy Assigns your application to Institute(s) or center for funding consideration Review group for review of scientific and technical merit If you have questions during these stages, please reach out to DRR: csrdrr@mail.nih.gov

  6. Applications Are Assigned to: Institutes or Centers based on Overall mission and guidelines of the IC (Institute/Center) Specific programmatic mandates and interests of the IC Applications can only be assigned to ICs participating in the FOA Scientific review groups based on Specific, published review guidelines for each review group Suggestions made in the Assignment Request Form are considered Referral Process: DRR Referral Officers Branch Chiefs SROs Applicant

  7. ENQUIRE: Overview and details https://public.csr.nih.gov/StudySections/CSREnquire 7

  8. Epidemiology and Population Health scientific review groups ended after summer 2022 review meetings Behavioral Genetics and Epidemiology (BGES) Biostatistical Methods and Research Design (BMRD) Cancer, Heart, and Sleep Epidemiology Panel A (CHSA) Cancer, Heart, and Sleep Epidemiology Panel B (CHSB) Clinical Research & Field Studies of Infectious Disease* (CRFS) Infectious Diseases, Reproductive Health, Asthma and Pulmonary Conditions* (IRAP) Kidney, Nutrition, Obesity, and Diabetes (KNOD) Neurological, Aging and Musculoskeletal Epidemiology* (NAME) (*and overflow SEPs) Revised scope after 2022 review meetings: Genetics of Health and Disease (GHD)

  9. New Epidemiology and Population Health Branch Conceptual Framework Aging, Injury, Musculoskeletal, and Rheumatologic Disorders (AIMR) Reproductive, Perinatal, and Pediatric Health (RPPH) Population-based Research in Infectious Disease (PRID) Cancer and Hematological Disorders (CHD) Cardiovascular and Respiratory Diseases (CRD) Kidney, Endocrine, and Digestive Disorders (KEDD) Neurological, Mental, and Behavioral Health (NMBH) Health States Data/Methods Exposure Lifestyle and Health Behaviors (LHB) Social and Environmental Determinants of Health (SEDH) Analytics and Statistics for Population Research panel A (ASPA) Analytics and Statistics for Population Research panel B (ASPB)

  10. CHD study section scope and topics Scope: reviews applications that seek to understand the etiology, determinants, distribution and outcomes of cancer and hematologic disorders, conditions and phenotypes from a population health perspective. Topics: Incidence, prevalence, progression and consequences of cancers in large populations including the focus on early detection, survivorship and recurrence Incidence, prevalence, progression and consequences of hematologic disease and phenotypes in large populations, including but not limited to anemias, disorders of coagulation, lymphomas and leukemias Effects of environmental and other exposures on incidence, progression, and outcomes related to cancer and hematologic disorders in large populations Incidence, prevalence and determinants of co-morbidities and multi- morbidities in populations with cancer and hematological disorders

  11. CRD study section scope and topics Scope: reviews applications that seek to understand the etiology, determinants, distribution and outcomes of cardiovascular and respiratory phenotypes, disorders and diseases from a population health perspective. Topics: Incidence, prevalence, progression and consequences of cardiovascular and disorders in large populations that include but are not limited to heart failure, atherosclerosis, pulmonary vascular disease and myocardial infarction Incidence, prevalence, progression and consequences of respiratory diseases and disorders in large populations that include but are not limited to chronic obstructive pulmonary disease (COPD), asthma, and bronchopulmonary dysplasia Effects of environmental and other exposures on incidence, progression, and outcomes related to cardiovascular and respiratory health in large populations, especially with a focus on the disease or disorder outcome rather than the exposure Incidence, prevalence and determinants of co-morbidities and multi-morbidities in populations with cardiovascular and respiratory diseases

  12. Examples of study sections of shared interest with CHD Social and Environmental Determinants of Health SEDH Clinical Integrative Cardiovascular and Hematological Sciences CCHS Clinical Oncology Study Section CONC Cardiovascular and Respiratory Diseases CRD (epi) Lifestyle and Health Behaviors LHB Effect of Social, Environmental and Health Behaviors on Cancer and Hematological Disorders Clinical research of Hematological Disorders and Cancer CHD Genetic predisposition to cancer and hematological disorders Cancer Genetics Study Section CG Molecular Cancer Diagnosis and Classification MCDC Analytics and Statistics for Population Research Panel A ASPA Ethnic and racial disparities in cancer outcomes Basic Mechanisms in Cancer Health Disparities BMCD

  13. Study Sections that have typically reviewed Cancer-related Cardiotoxicity applications: Retired Study Sections CHSA CHSB CICS CCHF MIM Now Covered by Cancer and Hematologic Disorders (CHD) Cardiovascular and Respiratory Disorders (CRD) Clinical Integrative Cardiovascular and Hematologic Sciences (CCHS) Integrative Myocardial Physiology / Pathophysiology A / B (MPPA and MPPB) Health Services Quality and Effectiveness (HSQE) Organization and Delivery of Health Services (ODHS) Clinical Management in General Care Settings (CMGC) Interdisciplinary Clinical Care in Specialty Care Settings (ICSC) Advanced Therapeutics (ATA) HSOD NRCS DT RTB Radiation Therapeutics and Biology (RTB) https://public.csr.nih.gov/StudySections

  14. Assignment Request Form (ARF) Not required Suggest assignments (study section and institute) Identify potential conflicts of interest List areas of expertise needed to evaluate the application Speak freely! This form will not be part of the assembled application; it will not be made available to program or to reviewers.

  15. Who Can Answer Your Questions? Before you submit your application A program officer (PO) at an NIH Institute or Center Scientific review officer (SRO) CSR Division of Receipt and Referral (csrdrr@mail.nih.gov) After you submit Your SRO CSR Division of Receipt and Referral (csrdrr@mail.nih.gov) After your review Your assigned PO Grants Info: GrantsInfo@od.nih.gov 301 945-7573

  16. Serve on a Review Panel Established Investigators can serve as Ad Hoc or Regular Members say yes when invited! Early career scientists can enroll in CSR s early career reviewer (ECR) program. ECR s serve one time and review 2 applications as Reviewere#3. For ECR qualifications and application process. https://public.csr.nih.gov/ForRevie wers/BecomeAReviewer/ECR Aimed at early career, independent scientists postdocs are not eligible and tenured professors are not eligible Review experience and successful competition for an R01 or equivalent are disqualifiers.

  17. Other Resources Webinars - Early Career Reviewer Panel Q & A and Grants 101 - https://public.csr.nih.gov/NewsAndPolicy/PeerReviewVideos Sample applications at https://www.niaid.nih.gov/grants- contracts/sample-applications

  18. Key NIH Review and Grants Web Sites NIH Center for Scientific Review http://www.csr.nih.gov NIH Office of Extramural Research http://grants.nih.gov/

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