Sleep and Epilepsy: Tips for a Restful Night

Getting a Good Night’s Sleep
with Epilepsy
Eilis Boudreau M.D., Ph.D.
Portland VA Medical Center
Epilepsy Center of Excellence & Sleep
Medicine Program
 
Outline
What is the function of sleep?
How much sleep do we need?
Sleep Basics
Common sleep disorders
Best Sleep Practices
Why do we sleep?
 
Sleep Requirements
Average adult: 7.5-8 hours
Epidemiology: sleep>9 hours or <4 hours have
higher chance of death secondary to CAD,
stroke and cancer vs 7-8 hour/night sleepers
During pre-light bulb Victorian era, average
sleep times closer to 10 hrs/day
HOW MUCH SLEEP DO WE GET?
Epidemiology:
2006 CDC Report
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a2.htm
SLEEP BASICS
Sleep Basics
Drive to sleep driven by:
Internal body clock (circadian)
How much sleep debt we’ve built up
Regulation of Sleep
From “Update on the Science, Diagnosis and Management of Insomnia”, ed
Gary Richardson, 2006, pg. 13.
Nighttime Sleep Cycles
Each cycle last approximately 90-110 minutes
4-6 cycles per night
During first cycles Rapid Eye Movement (REM)
component only a few minutes
First 2 cycles have significant slow wave sleep
Later cycles dominated by REM
COMMON SLEEP DISORDERS
Most Common Sleep Disorders
Restless Leg Syndrome
Sleep-disordered breathing
Insomnia
Restless Leg Syndrome
Clinical diagnosis
 
- Urge to move legs
 
- Begins or worsens during rest
 
- Relieved with movement
 
- Worst or only occurs at night
RLS: Epidemiology
Two peaks of incidence
 
- 2
nd
 decade
 
- 4
th
 and 5
th
 decades
RLS Treatment
Dopamine agonists (ex. ropinirole)
Other treatments include gabapentin,
clonazepam, narcotic meds for very resistant
cases
Non-pharmacological: decrease caffeine,
nicotine, alcohol;  massage legs; warm baths
before bedtime
Sleep Disordered Breathing
Episodes of difficulty breathing or cessation of
breathing for at least 10 seconds
Sleep Disordered Breathing
Snoring (but many people snore and DON’T
have apnea)
Witnessed apneas
Excessive daytime sleepiness
AM headaches
Dry mouth
Factors that Increase Risk for Sleep-
Disordered Breathing?
Being overweight
Larger neck circumference
Being a male
Increased age
Post-menopausal
Obstructive Sleep Apnea:
Epidemiology
5% - 20% adults
Males > Females
Why treat Sleep-Disordered
Breathing?
Short-term: patients feel better and function
better
Long-term: prevent long-term complications
of apnea
Sleep Apnea and Epilepsy
Treatment of sleep apnea may improve
seizure control
Diagnosis and Treatment of
Sleep Apnea
Diagnosis: Overnight sleep study in the sleep
laboratory
Treatment: CPAP
Insomnia
Multiple causes.
Is a symptom, many times of multiple issues.
Need to evaluate underlying problems to get
at root cause.
Insomnia and Epilepsy
Increased awakenings in patients with
epilepsy
?seizures
?medication side-effects (lamotrigene, felbamate,
levetiracetam)
BEST SLEEP PRACTICES
Best Sleep Practices
Set-up bedroom only for sleep.
Have a regular sleep routine.
Keep a regular bedtime and wake time.
Protect your sleep time from other activities.
Avoid alcohol before bedtime.
Limit caffeinated beverages.
Sleep in Epilepsy
Seizures at night common with some types of
epilepsy.
Seizures can disrupt normal sleep.
Sleep-deprivation may trigger seizures.
Depression and anxiety more common in
epilepsy and also disrupt sleep.
Sleep, Epilepsy, and Alcohol
Alcohol may increase chance of seizure
(especially binge drinking)
Alcohol significantly disrupts sleep
Significant alcohol intake not good for seizure
control or sleep
Summary of What We Know
About Sleep and Epilepsy
Poorer sleep quality
Apnea may be more common and treatment
may improve seizure control
Antiepileptic medications may worsen sleep
(fragment sleep, increase insomnia)
BEST SLEEP PRACTICES
Best Sleep Practices
Set-up bedroom only for sleep.
Have a regular sleep routine.
Keep a regular bedtime and wake time.
Protect your sleep time from other activities.
Avoid alcohol before bedtime.
Limit caffeinated beverages.
Improving Sleep in Epilepsy
Optimize epilepsy treatment
Discuss any medication side-effects with care
provider
Practice good sleep hygiene
Identify and treat sleep disorders such as
apnea
Tell you care provider if you develop sleep
problems
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Delve into the intricate relationship between epilepsy and sleep, exploring the functions of sleep, optimal sleep durations, common sleep disorders, and best practices for quality sleep. Uncover valuable insights such as why we sleep, sleep requirements for adults, epidemiological data on sleep insufficiency, basics of sleep regulation, and the stages of nighttime sleep cycles. Gain knowledge on how to promote better sleep hygiene and enhance overall well-being while managing epilepsy.

  • Sleep disorders
  • Epilepsy
  • Sleep hygiene
  • Sleep requirements
  • Neurology

Uploaded on Sep 25, 2024 | 0 Views


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  1. Getting a Good Nights Sleep with Epilepsy Eilis Boudreau M.D., Ph.D. Portland VA Medical Center Epilepsy Center of Excellence & Sleep Medicine Program

  2. Outline What is the function of sleep? How much sleep do we need? Sleep Basics Common sleep disorders Best Sleep Practices

  3. Why do we sleep?

  4. Sleep Requirements Average adult: 7.5-8 hours Epidemiology: sleep>9 hours or <4 hours have higher chance of death secondary to CAD, stroke and cancer vs 7-8 hour/night sleepers During pre-light bulb Victorian era, average sleep times closer to 10 hrs/day

  5. HOW MUCH SLEEP DO WE GET?

  6. Epidemiology: 2006 CDC Report 35.0% 32.6% 29.6% 30.0% 0 Days 25.0% 1-6 Days 20.0% 7-13 Days 12.9% 12.2% 15.0% 14-20 Days 10.1% 21-29 Days 10.0% 2.6% 30 Days 5.0% 0.0% # Days of insufficient sleep http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a2.htm

  7. SLEEP BASICS

  8. Sleep Basics Drive to sleep driven by: Internal body clock (circadian) How much sleep debt we ve built up

  9. Regulation of Sleep From Update on the Science, Diagnosis and Management of Insomnia , ed Gary Richardson, 2006, pg. 13.

  10. Nighttime Sleep Cycles Each cycle last approximately 90-110 minutes 4-6 cycles per night During first cycles Rapid Eye Movement (REM) component only a few minutes First 2 cycles have significant slow wave sleep Later cycles dominated by REM

  11. COMMON SLEEP DISORDERS

  12. Most Common Sleep Disorders Restless Leg Syndrome Sleep-disordered breathing Insomnia

  13. Restless Leg Syndrome Clinical diagnosis - Urge to move legs - Begins or worsens during rest - Relieved with movement - Worst or only occurs at night

  14. RLS: Epidemiology Two peaks of incidence - 2nd decade - 4th and 5th decades

  15. RLS Treatment Dopamine agonists (ex. ropinirole) Other treatments include gabapentin, clonazepam, narcotic meds for very resistant cases Non-pharmacological: decrease caffeine, nicotine, alcohol; massage legs; warm baths before bedtime

  16. Sleep Disordered Breathing Episodes of difficulty breathing or cessation of breathing for at least 10 seconds

  17. Sleep Disordered Breathing Snoring (but many people snore and DON T have apnea) Witnessed apneas Excessive daytime sleepiness AM headaches Dry mouth

  18. Factors that Increase Risk for Sleep- Disordered Breathing? Being overweight Larger neck circumference Being a male Increased age Post-menopausal

  19. Obstructive Sleep Apnea: Epidemiology 5% - 20% adults Males > Females

  20. Why treat Sleep-Disordered Breathing? Short-term: patients feel better and function better Long-term: prevent long-term complications of apnea

  21. Sleep Apnea and Epilepsy Treatment of sleep apnea may improve seizure control

  22. Diagnosis and Treatment of Sleep Apnea Diagnosis: Overnight sleep study in the sleep laboratory Treatment: CPAP

  23. Insomnia Multiple causes. Is a symptom, many times of multiple issues. Need to evaluate underlying problems to get at root cause.

  24. Insomnia and Epilepsy Increased awakenings in patients with epilepsy ?seizures ?medication side-effects (lamotrigene, felbamate, levetiracetam)

  25. BEST SLEEP PRACTICES

  26. Best Sleep Practices Set-up bedroom only for sleep. Have a regular sleep routine. Keep a regular bedtime and wake time. Protect your sleep time from other activities. Avoid alcohol before bedtime. Limit caffeinated beverages.

  27. Sleep in Epilepsy Seizures at night common with some types of epilepsy. Seizures can disrupt normal sleep. Sleep-deprivation may trigger seizures. Depression and anxiety more common in epilepsy and also disrupt sleep.

  28. Sleep, Epilepsy, and Alcohol Alcohol may increase chance of seizure (especially binge drinking) Alcohol significantly disrupts sleep Significant alcohol intake not good for seizure control or sleep

  29. Summary of What We Know About Sleep and Epilepsy Poorer sleep quality Apnea may be more common and treatment may improve seizure control Antiepileptic medications may worsen sleep (fragment sleep, increase insomnia)

  30. BEST SLEEP PRACTICES

  31. Best Sleep Practices Set-up bedroom only for sleep. Have a regular sleep routine. Keep a regular bedtime and wake time. Protect your sleep time from other activities. Avoid alcohol before bedtime. Limit caffeinated beverages.

  32. Improving Sleep in Epilepsy Optimize epilepsy treatment Discuss any medication side-effects with care provider Practice good sleep hygiene Identify and treat sleep disorders such as apnea Tell you care provider if you develop sleep problems

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