Pertusis
Pertusis
DR Abbas
Etiology
most of epidemic and sporodic
cases caused by Bordetella
pertusis and ocasionally by
bordetella para pertusis
Epidemiology
Pathogenesis
Clinical features
•
Disease course is prolonged and divided in to
three phase
•
Catarrhal stage(1-2wk)
characterized by
begins insidiously after I.P of an 3-12 days
with symptoms of congestion, rhinorrhea,low
grade fewer, sneezing, lacrimation, and
conjunctival hyperemia.
•
Paraxysmal stage
(2-6wks)
: cough begins as a
dry , intermittent, irritative hack and evolve
in to the inexorable paraxysms that are
hallmark of the ds
•
Pertusis, commonly known as whooping cough, is an acute respiratory infection caused by Bordetella pertusis. The disease is characterized by intense coughing episodes that can be debilitating. Learn about the etiology, epidemiology, pathogenesis, and clinical features of pertusis to enhance your knowledge and awareness of this contagious condition.
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Presentation Transcript
Pertusis DR Abbas
Acute respiratory infection , characterized by intense cough , preferably known as whooping cough.
Etiology Etiology most of epidemic and sporodic cases caused by Bordetella pertusis and ocasionally by bordetella para pertusis
Pathogenesis Bordetella organism are tiny , fastidious, gram negative coccobacilli that only colonize ciliated epithelium. Exact mechanism of disease symptomatology remains unknown. Pertusis toxin(PT) , the major virulence factor, has numerous biologic activities(e.g, histamine sensitivity, insulin secretion, lymphocytosis)
Clinical features Clinical features Disease course is prolonged and divided in to three phase Catarrhal stage(1-2wk) characterized by begins insidiously after I.P of an 3-12 days with symptoms of congestion, rhinorrhea,low grade fewer, sneezing, lacrimation, and conjunctival hyperemia. Paraxysmal stage (2-6wks): cough begins as a dry , intermittent, irritative hack and evolve in to the inexorable paraxysms that are hallmark of the ds
